Zinc in PDB 7zgr: Polymerase Module of Yeast Cpf in Complex with MPE1, the Ypim of CFT2 and the Pre-Cleaved CYC1 Rna

The binding sites of Zinc atom in the Polymerase Module of Yeast Cpf in Complex with MPE1, the Ypim of CFT2 and the Pre-Cleaved CYC1 Rna (pdb code 7zgr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Polymerase Module of Yeast Cpf in Complex with MPE1, the Ypim of CFT2 and the Pre-Cleaved CYC1 Rna, PDB code: 7zgr:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Polymerase Module of Yeast Cpf in Complex with MPE1, the Ypim of CFT2 and the Pre-Cleaved CYC1 Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Polymerase Module of Yeast Cpf in Complex with MPE1, the Ypim of CFT2 and the Pre-Cleaved CYC1 Rna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:130.2 occ:1.00 NE2 B:HIS85 2.1 73.4 1.0 SG B:CYS75 2.3 82.5 1.0 SG B:CYS67 2.3 87.9 1.0 SG B:CYS81 2.3 94.3 1.0 CD2 B:HIS85 3.0 65.9 1.0 CB B:CYS67 3.0 76.8 1.0 CB B:CYS81 3.0 79.6 1.0 CE1 B:HIS85 3.1 75.1 1.0 CB B:CYS75 3.5 72.4 1.0 N6 E:A2 4.0 87.8 1.0 CG B:HIS85 4.1 63.9 1.0 ND1 B:HIS85 4.2 66.7 1.0 CB B:TRP70 4.3 63.7 1.0 CA B:CYS67 4.5 72.2 1.0 O B:TYR83 4.5 92.0 1.0 CA B:CYS81 4.5 80.6 1.0 N B:TRP70 4.6 69.6 1.0 CA B:CYS75 4.7 68.5 1.0 CB B:TYR83 4.7 84.1 1.0 O B:ASN78 4.9 96.6 1.0

Zinc binding site 2 out of 2 in the Polymerase Module of Yeast Cpf in Complex with MPE1, the Ypim of CFT2 and the Pre-Cleaved CYC1 Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Polymerase Module of Yeast Cpf in Complex with MPE1, the Ypim of CFT2 and the Pre-Cleaved CYC1 Rna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn302 b:172.0 occ:1.00 NE2 B:HIS56 2.1 103.2 1.0 SG B:CYS34 2.3 117.9 1.0 SG B:CYS46 2.3 123.0 1.0 SG B:CYS52 2.3 123.4 1.0 CE1 B:HIS56 3.0 100.3 1.0 CB B:CYS52 3.0 108.8 1.0 CB B:CYS34 3.1 101.1 1.0 CD2 B:HIS56 3.1 101.9 1.0 CB B:CYS46 3.8 119.6 1.0 NH2 B:ARG48 3.8 109.3 1.0 NE B:ARG48 4.0 112.5 1.0 ND1 B:HIS56 4.1 98.1 1.0 CG B:HIS56 4.2 99.1 1.0 CZ B:ARG48 4.4 111.0 1.0 CA B:CYS52 4.5 105.7 1.0 CA B:CYS34 4.5 102.4 1.0 CB B:TYR37 4.5 101.1 1.0 N B:TYR37 4.7 101.4 1.0 CB B:LYS54 4.8 95.3 1.0 CA B:CYS46 4.9 118.3 1.0 CB B:PHE36 4.9 108.9 1.0 CB B:ARG48 4.9 105.7 1.0 O B:GLY49 4.9 109.7 1.0

J.B.Rodriguez-Molina, F.J.O'reilly, H.Fagarasan, E.Sheekey, S.Maslen, J.M.Skehel, J.Rappsilber, L.A.Passmore. MPE1 Senses the Binding of Pre-Mrna and Controls 3' End Processing By Cpf. Mol.Cell V. 82 2490 2022.
ISSN: ISSN 1097-2765
PubMed: 35584695
DOI: 10.1016/J.MOLCEL.2022.04.021