Zinc in PDB 7zey: Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription

All present enzymatic activity of Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription:
5.2.1.8;

The binding sites of Zinc atom in the Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription (pdb code 7zey). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription, PDB code: 7zey:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1701 b:0.0 occ:1.00 ND1 B:HIS1596 2.0 0.0 1.0 SG B:CYS1569 2.3 0.0 1.0 SG B:CYS1599 2.3 0.0 1.0 SG B:CYS1572 2.3 0.0 1.0 HB2 B:HIS1596 2.9 0.0 1.0 CE1 B:HIS1596 3.0 0.0 1.0 CG B:HIS1596 3.1 0.0 1.0 HB3 B:CYS1569 3.2 0.0 1.0 HE1 B:HIS1596 3.3 0.0 1.0 HB3 B:CYS1572 3.3 0.0 1.0 CB B:CYS1569 3.3 0.0 1.0 CB B:CYS1599 3.4 0.0 1.0 CB B:CYS1572 3.5 0.0 1.0 HB2 B:CYS1599 3.5 0.0 1.0 CB B:HIS1596 3.5 0.0 1.0 HB3 B:CYS1599 3.6 0.0 1.0 HB2 B:CYS1569 3.6 0.0 1.0 H B:HIS1596 3.7 0.0 1.0 HB2 B:LYS1574 3.7 0.0 1.0 H B:CYS1572 4.0 0.0 1.0 NE2 B:HIS1596 4.2 0.0 1.0 HB2 B:LEU1571 4.2 0.0 1.0 N B:CYS1572 4.2 0.0 1.0 CD2 B:HIS1596 4.2 0.0 1.0 HB2 B:CYS1572 4.3 0.0 1.0 HB3 B:HIS1596 4.3 0.0 1.0 HD2 B:LYS1574 4.3 0.0 1.0 CA B:CYS1572 4.4 0.0 1.0 H B:CYS1599 4.5 0.0 1.0 N B:HIS1596 4.5 0.0 1.0 H B:LYS1574 4.6 0.0 1.0 CA B:HIS1596 4.6 0.0 1.0 H B:LEU1571 4.7 0.0 1.0 CA B:CYS1569 4.7 0.0 1.0 O B:HIS1596 4.8 0.0 1.0 CA B:CYS1599 4.8 0.0 1.0 O B:CYS1569 4.8 0.0 1.0 CB B:LYS1574 4.8 0.0 1.0 C B:LEU1571 4.8 0.0 1.0 C B:CYS1572 4.9 0.0 1.0 O B:CYS1572 5.0 0.0 1.0 C B:CYS1569 5.0 0.0 1.0 N B:CYS1599 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1702 b:0.0 occ:1.00 SG B:CYS1588 2.3 0.0 1.0 SG B:CYS1624 2.3 0.0 1.0 SG B:CYS1621 2.3 0.0 1.0 SG B:CYS1591 2.3 0.0 1.0 HB2 B:CYS1624 3.2 0.0 1.0 H B:CYS1621 3.2 0.0 1.0 CB B:CYS1588 3.3 0.0 1.0 HB3 B:CYS1621 3.3 0.0 1.0 HB3 B:CYS1588 3.3 0.0 1.0 HB3 B:CYS1591 3.4 0.0 1.0 CB B:CYS1624 3.4 0.0 1.0 HB2 B:CYS1588 3.4 0.0 1.0 CB B:CYS1621 3.4 0.0 1.0 CB B:CYS1591 3.5 0.0 1.0 H B:CYS1624 3.7 0.0 1.0 H B:CYS1591 3.9 0.0 1.0 N B:CYS1621 4.0 0.0 1.0 HB B:THR1620 4.0 0.0 1.0 HG3 B:LYS1590 4.0 0.0 1.0 HB3 B:CYS1624 4.1 0.0 1.0 N B:CYS1591 4.1 0.0 1.0 N B:CYS1624 4.2 0.0 1.0 HH21 B:ARG1593 4.2 0.0 1.0 CA B:CYS1621 4.2 0.0 1.0 H B:LYS1590 4.2 0.0 1.0 CA B:CYS1591 4.3 0.0 1.0 HB2 B:CYS1621 4.3 0.0 1.0 HB2 B:CYS1591 4.3 0.0 1.0 HB3 B:ARG1593 4.3 0.0 1.0 CA B:CYS1624 4.4 0.0 1.0 HE B:ARG1593 4.4 0.0 1.0 H B:ASN1623 4.4 0.0 1.0 HG2 B:LYS1590 4.6 0.0 1.0 HB2 B:ASN1623 4.6 0.0 1.0 CA B:CYS1588 4.7 0.0 1.0 O B:CYS1591 4.7 0.0 1.0 C B:CYS1591 4.7 0.0 1.0 C B:CYS1621 4.8 0.0 1.0 O B:CYS1621 4.8 0.0 1.0 H B:GLY1589 4.8 0.0 1.0 HA B:CYS1624 4.8 0.0 1.0 H B:ARG1593 4.8 0.0 1.0 CG B:LYS1590 4.8 0.0 1.0 C B:LYS1590 4.9 0.0 1.0 HA B:CYS1588 5.0 0.0 1.0 CB B:THR1620 5.0 0.0 1.0

M.Blatter, F.Allain, C.Meylan. Rna Binding Induces An Allosteric Switch in CYP33 to Repress MLL1 Mediated Transcription To Be Published.