Zinc in PDB 7z8v: CAND1-Scf-SKP2 (SKP1DELDEL) CAND1 Engaged Scf Rocked

The binding sites of Zinc atom in the CAND1-Scf-SKP2 (SKP1DELDEL) CAND1 Engaged Scf Rocked (pdb code 7z8v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the CAND1-Scf-SKP2 (SKP1DELDEL) CAND1 Engaged Scf Rocked, PDB code: 7z8v:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the CAND1-Scf-SKP2 (SKP1DELDEL) CAND1 Engaged Scf Rocked


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of CAND1-Scf-SKP2 (SKP1DELDEL) CAND1 Engaged Scf Rocked within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn201 b:77.0 occ:1.00 ND1 R:HIS80 2.0 65.8 1.0 SG R:CYS45 2.3 76.6 1.0 SG R:CYS42 2.3 72.5 1.0 SG R:CYS83 2.3 64.7 1.0 CE1 R:HIS80 2.8 65.8 1.0 CB R:CYS42 2.9 72.5 1.0 CG R:HIS80 3.1 65.8 1.0 CB R:CYS45 3.5 76.6 1.0 CB R:CYS83 3.6 64.7 1.0 CB R:HIS80 3.6 65.8 1.0 N R:CYS45 3.9 76.6 1.0 NE2 R:HIS80 4.0 65.8 1.0 O R:CYS45 4.0 76.6 1.0 CA R:CYS45 4.2 76.6 1.0 CD2 R:HIS80 4.2 65.8 1.0 N R:HIS80 4.3 65.8 1.0 CA R:CYS42 4.4 72.5 1.0 C R:CYS45 4.5 76.6 1.0 CA R:HIS80 4.6 65.8 1.0 CA R:CYS83 5.0 64.7 1.0 C R:ILE44 5.0 70.1 1.0 C R:CYS42 5.0 72.5 1.0

Zinc binding site 2 out of 3 in the CAND1-Scf-SKP2 (SKP1DELDEL) CAND1 Engaged Scf Rocked


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of CAND1-Scf-SKP2 (SKP1DELDEL) CAND1 Engaged Scf Rocked within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn202 b:65.7 occ:1.00 OD2 R:ASP97 2.0 58.9 1.0 ND1 R:HIS77 2.0 49.8 1.0 SG R:CYS94 2.3 56.2 1.0 SG R:CYS75 2.3 49.0 1.0 CE1 R:HIS77 2.9 49.8 1.0 CG R:ASP97 3.1 58.9 1.0 CG R:HIS77 3.1 49.8 1.0 CB R:CYS94 3.4 56.2 1.0 CB R:CYS75 3.4 49.0 1.0 CB R:HIS77 3.5 49.8 1.0 OD1 R:ASP97 3.7 58.9 1.0 NE2 R:HIS77 4.0 49.8 1.0 N R:ASP97 4.1 58.9 1.0 CB R:ASP97 4.1 58.9 1.0 CD2 R:HIS77 4.2 49.8 1.0 CB R:LEU96 4.6 55.3 1.0 CZ3 R:TRP101 4.6 51.7 1.0 CA R:ASP97 4.6 58.9 1.0 O R:CYS75 4.7 49.0 1.0 CA R:CYS75 4.7 49.0 1.0 O R:ASP97 4.7 58.9 1.0 CA R:CYS94 4.8 56.2 1.0 CA R:HIS77 4.8 49.8 1.0 C R:CYS75 4.9 49.0 1.0 CE3 R:TRP101 4.9 51.7 1.0 C R:LEU96 4.9 55.3 1.0 N R:LEU96 4.9 55.3 1.0 N R:HIS77 4.9 49.8 1.0

Zinc binding site 3 out of 3 in the CAND1-Scf-SKP2 (SKP1DELDEL) CAND1 Engaged Scf Rocked


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of CAND1-Scf-SKP2 (SKP1DELDEL) CAND1 Engaged Scf Rocked within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn203 b:86.6 occ:1.00 ND1 R:HIS82 2.0 69.7 1.0 SG R:CYS68 2.3 80.2 1.0 SG R:CYS56 2.3 86.7 1.0 SG R:CYS53 2.3 83.9 1.0 CE1 R:HIS82 2.9 69.7 1.0 CB R:CYS53 3.1 83.9 1.0 CG R:HIS82 3.1 69.7 1.0 CB R:HIS82 3.5 69.7 1.0 CB R:CYS56 3.6 86.7 1.0 CB R:CYS68 3.6 80.2 1.0 N R:CYS53 3.8 83.9 1.0 CA R:CYS53 4.1 83.9 1.0 NE2 R:HIS82 4.1 69.7 1.0 CD2 R:HIS82 4.2 69.7 1.0 CA R:CYS68 4.4 80.2 1.0 CA R:HIS82 4.8 69.7 1.0 N R:HIS82 4.8 69.7 1.0 CA R:CYS56 4.9 86.7 1.0 C R:LEU52 4.9 82.6 1.0

K.Baek, D.C.Scott, L.T.Henneberg, M.T.King, M.Mann, B.A.Schulman. Systemwide Disassembly and Assembly of Scf Ubiquitin Ligase Complexes. Cell 2023.
ISSN: ISSN 1097-4172
PubMed: 37028429
DOI: 10.1016/J.CELL.2023.02.035