Zinc in PDB 7z8t: CAND1-Scf-SKP2 CAND1 Engaged Scf Rocked

Zinc Binding Sites:

The binding sites of Zinc atom in the CAND1-Scf-SKP2 CAND1 Engaged Scf Rocked (pdb code 7z8t). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the CAND1-Scf-SKP2 CAND1 Engaged Scf Rocked, PDB code: 7z8t:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in 7z8t

Go back to Zinc Binding Sites List in 7z8t
Zinc binding site 1 out of 3 in the CAND1-Scf-SKP2 CAND1 Engaged Scf Rocked


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of CAND1-Scf-SKP2 CAND1 Engaged Scf Rocked within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn201

b:76.4
occ:1.00
ND1 R:HIS80 2.0 65.4 1.0
SG R:CYS45 2.3 77.2 1.0
SG R:CYS83 2.3 64.9 1.0
SG R:CYS42 2.3 73.7 1.0
CE1 R:HIS80 2.8 65.4 1.0
CB R:CYS42 2.9 73.7 1.0
CG R:HIS80 3.2 65.4 1.0
CB R:CYS45 3.5 77.2 1.0
CB R:CYS83 3.6 64.9 1.0
CB R:HIS80 3.7 65.4 1.0
N R:CYS45 3.8 77.2 1.0
O R:CYS45 3.9 77.2 1.0
NE2 R:HIS80 4.0 65.4 1.0
CA R:CYS45 4.1 77.2 1.0
CD2 R:HIS80 4.2 65.4 1.0
N R:HIS80 4.4 65.4 1.0
CA R:CYS42 4.4 73.7 1.0
C R:CYS45 4.4 77.2 1.0
CA R:HIS80 4.7 65.4 1.0
SG R:CYS53 4.9 86.8 1.0
C R:CYS42 4.9 73.7 1.0
CA R:CYS83 4.9 64.9 1.0
C R:ILE44 5.0 70.4 1.0

Zinc binding site 2 out of 3 in 7z8t

Go back to Zinc Binding Sites List in 7z8t
Zinc binding site 2 out of 3 in the CAND1-Scf-SKP2 CAND1 Engaged Scf Rocked


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of CAND1-Scf-SKP2 CAND1 Engaged Scf Rocked within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn202

b:69.2
occ:1.00
OD2 R:ASP97 2.0 61.9 1.0
ND1 R:HIS77 2.0 53.2 1.0
SG R:CYS75 2.3 51.6 1.0
SG R:CYS94 2.3 59.3 1.0
CE1 R:HIS77 2.8 53.2 1.0
CG R:ASP97 3.1 61.9 1.0
CG R:HIS77 3.2 53.2 1.0
CB R:CYS75 3.3 51.6 1.0
CB R:CYS94 3.4 59.3 1.0
CB R:HIS77 3.7 53.2 1.0
OD1 R:ASP97 3.7 61.9 1.0
NE2 R:HIS77 4.0 53.2 1.0
N R:ASP97 4.1 61.9 1.0
CB R:ASP97 4.1 61.9 1.0
CD2 R:HIS77 4.2 53.2 1.0
O R:ASP97 4.6 61.9 1.0
CZ3 R:TRP101 4.6 51.3 1.0
CB R:LEU96 4.6 59.4 1.0
CA R:ASP97 4.6 61.9 1.0
CA R:CYS75 4.6 51.6 1.0
O R:CYS75 4.8 51.6 1.0
CE3 R:TRP101 4.8 51.3 1.0
CA R:CYS94 4.8 59.3 1.0
C R:CYS75 4.8 51.6 1.0
CA R:HIS77 4.9 53.2 1.0
N R:HIS77 4.9 53.2 1.0
N R:LEU96 5.0 59.4 1.0

Zinc binding site 3 out of 3 in 7z8t

Go back to Zinc Binding Sites List in 7z8t
Zinc binding site 3 out of 3 in the CAND1-Scf-SKP2 CAND1 Engaged Scf Rocked


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of CAND1-Scf-SKP2 CAND1 Engaged Scf Rocked within 5.0Å range:
probe atom residue distance (Å) B Occ
R:Zn203

b:85.8
occ:1.00
ND1 R:HIS82 2.0 69.2 1.0
SG R:CYS68 2.3 80.6 1.0
SG R:CYS56 2.3 91.9 1.0
SG R:CYS53 2.3 86.8 1.0
CB R:CYS53 2.8 86.8 1.0
CE1 R:HIS82 2.9 69.2 1.0
CG R:HIS82 3.1 69.2 1.0
CB R:HIS82 3.5 69.2 1.0
CB R:CYS68 3.6 80.6 1.0
N R:CYS53 3.7 86.8 1.0
CB R:CYS56 3.7 91.9 1.0
CA R:CYS53 3.8 86.8 1.0
NE2 R:HIS82 4.1 69.2 1.0
CD2 R:HIS82 4.2 69.2 1.0
CA R:CYS68 4.4 80.6 1.0
CA R:HIS82 4.8 69.2 1.0
N R:HIS82 4.8 69.2 1.0
C R:LEU52 4.9 85.6 1.0
CA R:CYS56 5.0 91.9 1.0
C R:CYS53 5.0 86.8 1.0

Reference:

K.Baek, D.C.Scott, L.T.Henneberg, M.T.King, M.Mann, B.A.Schulman. Systemwide Disassembly and Assembly of Scf Ubiquitin Ligase Complexes. Cell 2023.
ISSN: ISSN 1097-4172
PubMed: 37028429
DOI: 10.1016/J.CELL.2023.02.035
Page generated: Wed Apr 26 00:31:13 2023

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