Zinc in PDB 7yva: Crystal Structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase Complexed with Lipoic Acid

The structure of Crystal Structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase Complexed with Lipoic Acid, PDB code: 7yva was solved by H.Cao, Y.Huang, Y.Ren, J.Wan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.37 / 2.93
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	159.181, 56.622, 81.839, 90, 96.33, 90
R / Rfree (%)	20.4 / 25.8

The binding sites of Zinc atom in the Crystal Structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase Complexed with Lipoic Acid (pdb code 7yva). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase Complexed with Lipoic Acid, PDB code: 7yva:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase Complexed with Lipoic Acid


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase Complexed with Lipoic Acid within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:74.6 occ:1.00 OE1 A:GLU173 2.0 73.4 1.0 OE2 A:GLU173 2.2 77.8 1.0 NE2 A:HIS109 2.2 67.4 1.0 NE2 A:HIS225 2.3 74.3 1.0 ND1 A:HIS264 2.3 73.3 1.0 CD A:GLU173 2.4 74.6 1.0 CE1 A:HIS225 3.1 76.9 1.0 CE1 A:HIS264 3.2 70.2 1.0 CD2 A:HIS109 3.2 66.7 1.0 CE1 A:HIS109 3.2 66.4 1.0 O A:HOH514 3.3 69.3 1.0 CD2 A:HIS225 3.3 73.8 1.0 CG A:HIS264 3.4 73.3 1.0 CB A:HIS264 3.8 76.9 1.0 CG A:GLU173 3.8 71.8 1.0 ND1 A:HIS225 4.2 77.6 1.0 CG A:HIS225 4.3 74.7 1.0 ND1 A:HIS109 4.3 65.3 1.0 NE2 A:HIS264 4.4 69.4 1.0 CG A:HIS109 4.4 64.7 1.0 OD2 A:ASP143 4.4 72.0 1.0 CD2 A:HIS264 4.5 71.1 1.0 CB A:GLU173 4.6 68.5 1.0 CG A:ASP143 4.7 67.4 1.0 OD1 A:ASP143 4.9 68.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase Complexed with Lipoic Acid


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase Complexed with Lipoic Acid within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:81.0 occ:1.00 OE1 B:GLU173 1.9 77.5 1.0 OE2 B:GLU173 2.0 79.1 1.0 CD B:GLU173 2.2 78.5 1.0 NE2 B:HIS109 2.3 77.4 1.0 NE2 B:HIS225 2.3 72.5 1.0 ND1 B:HIS264 2.3 76.9 1.0 CE1 B:HIS109 2.9 76.0 1.0 CE1 B:HIS264 3.1 75.6 1.0 CE1 B:HIS225 3.2 73.7 1.0 CD2 B:HIS225 3.3 73.3 1.0 CG B:HIS264 3.4 74.7 1.0 CD2 B:HIS109 3.5 78.1 1.0 CG B:GLU173 3.7 80.3 1.0 CB B:HIS264 3.8 73.7 1.0 ND1 B:HIS109 4.1 76.3 1.0 NE2 B:HIS264 4.3 75.0 1.0 ND1 B:HIS225 4.3 74.3 1.0 CG B:HIS225 4.4 73.6 1.0 CG B:HIS109 4.4 76.2 1.0 CD2 B:HIS264 4.4 74.4 1.0 CB B:GLU173 4.5 81.0 1.0 CG B:ASP143 4.7 83.2 1.0 OD1 B:ASP143 4.8 85.6 1.0 OD2 B:ASP143 4.9 83.4 1.0

H.Cao, Y.Huang, Y.Ren, J.Wan. Crystal Structure of Candida Albicans Fructose-1,6-Bisphosphate Aldolase Complexed with Lipoic Acid To Be Published.