Zinc in PDB 7y75: SIT1-ACE2-Ba.2 Rbd

All present enzymatic activity of SIT1-ACE2-Ba.2 Rbd:
3.4.17.23;

The binding sites of Zinc atom in the SIT1-ACE2-Ba.2 Rbd (pdb code 7y75). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the SIT1-ACE2-Ba.2 Rbd, PDB code: 7y75:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the SIT1-ACE2-Ba.2 Rbd


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of SIT1-ACE2-Ba.2 Rbd within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn902 b:55.1 occ:1.00 OE2 A:GLU402 1.9 35.9 1.0 NE2 A:HIS374 2.0 42.5 1.0 CE1 A:HIS378 2.2 38.8 1.0 CD A:GLU402 2.5 35.9 1.0 OE1 A:GLU402 2.5 35.9 1.0 NE2 A:HIS378 2.9 38.8 1.0 CE1 A:HIS374 3.0 42.5 1.0 CD2 A:HIS374 3.0 42.5 1.0 ND1 A:HIS378 3.3 38.8 1.0 CG A:GLU402 4.0 35.9 1.0 ND1 A:HIS374 4.1 42.5 1.0 CD2 A:HIS378 4.1 38.8 1.0 CG A:HIS374 4.1 42.5 1.0 CG A:HIS378 4.3 38.8 1.0 OE1 A:GLU375 4.4 47.1 1.0 CA A:GLU402 4.8 35.9 1.0 OE2 A:GLU375 4.8 47.1 1.0 CB A:GLU402 4.8 35.9 1.0 CD A:GLU375 5.0 47.1 1.0

Zinc binding site 2 out of 2 in the SIT1-ACE2-Ba.2 Rbd


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of SIT1-ACE2-Ba.2 Rbd within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn902 b:55.5 occ:1.00 OE2 C:GLU402 1.9 35.8 1.0 NE2 C:HIS374 2.0 42.1 1.0 CE1 C:HIS378 2.2 38.5 1.0 CD C:GLU402 2.5 35.8 1.0 OE1 C:GLU402 2.5 35.8 1.0 NE2 C:HIS378 2.9 38.5 1.0 CE1 C:HIS374 3.0 42.1 1.0 CD2 C:HIS374 3.0 42.1 1.0 ND1 C:HIS378 3.3 38.5 1.0 CG C:GLU402 4.0 35.8 1.0 ND1 C:HIS374 4.1 42.1 1.0 CD2 C:HIS378 4.1 38.5 1.0 CG C:HIS374 4.1 42.1 1.0 CG C:HIS378 4.3 38.5 1.0 OE1 C:GLU375 4.4 46.6 1.0 CA C:GLU402 4.8 35.8 1.0 OE2 C:GLU375 4.8 46.6 1.0 CB C:GLU402 4.8 35.8 1.0 CD C:GLU375 5.0 46.6 1.0

Y.Shen, J.Wang, Y.Li, Y.Zhang, R.Tian, R.Yan. Structures of ACE2-SIT1 Recognized By Omicron Variants of Sars-Cov-2. Cell Discov V. 8 123 2022.
ISSN: ESSN 2056-5968
PubMed: 36384914
DOI: 10.1038/S41421-022-00488-X