Zinc in PDB 7y5q: Structure of 1:1 Papp-A.STC2 Complex(Half Map)

All present enzymatic activity of Structure of 1:1 Papp-A.STC2 Complex(Half Map):
3.4.24.79;

The binding sites of Zinc atom in the Structure of 1:1 Papp-A.STC2 Complex(Half Map) (pdb code 7y5q). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of 1:1 Papp-A.STC2 Complex(Half Map), PDB code: 7y5q:

Zinc binding site 1 out of 1 in the Structure of 1:1 Papp-A.STC2 Complex(Half Map)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of 1:1 Papp-A.STC2 Complex(Half Map) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1601 b:19.8 occ:1.00 CE1 B:HIS492 1.8 9.9 1.0 CE1 B:HIS482 2.0 6.5 1.0 NE2 B:HIS486 2.3 2.4 1.0 NE2 B:HIS482 2.3 6.5 1.0 NE2 B:HIS492 2.3 9.9 1.0 ND1 B:HIS492 3.0 9.9 1.0 CD2 B:HIS486 3.1 2.4 1.0 ND1 B:HIS482 3.3 6.5 1.0 CE1 B:HIS486 3.4 2.4 1.0 CD2 B:HIS492 3.6 9.9 1.0 CD2 B:HIS482 3.7 6.5 1.0 CG B:HIS492 3.9 9.9 1.0 OH B:TYR558 3.9 22.1 1.0 CD1 B:LEU445 4.0 35.9 1.0 CG B:HIS482 4.1 6.5 1.0 CE1 B:TYR558 4.2 22.1 1.0 CG B:HIS486 4.3 2.4 1.0 CZ B:TYR558 4.4 22.1 1.0 ND1 B:HIS486 4.4 2.4 1.0 CG B:LEU445 4.6 35.9 1.0 CD2 B:LEU445 4.8 35.9 1.0

Q.Zhong, H.Chu, G.Wang, C.Zhang, R.Li, F.Guo, X.Meng, X.Lei, Y.Zhou, R.Ren, L.Tao, N.Li, N.Gao, Y.Wei, J.Qiao, J.Hang. Structural Insights Into the Covalent Regulation of Papp-A Activity By Prombp and STC2. Cell Discov V. 8 137 2022.
ISSN: ESSN 2056-5968
PubMed: 36550107
DOI: 10.1038/S41421-022-00502-2