Zinc in PDB 7xob: Sars-Cov-2 Omicron Ba.2 Variant Spike Trimer with Two Mouse ACE2 Bound

All present enzymatic activity of Sars-Cov-2 Omicron Ba.2 Variant Spike Trimer with Two Mouse ACE2 Bound:
3.4.17.23;

The binding sites of Zinc atom in the Sars-Cov-2 Omicron Ba.2 Variant Spike Trimer with Two Mouse ACE2 Bound (pdb code 7xob). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sars-Cov-2 Omicron Ba.2 Variant Spike Trimer with Two Mouse ACE2 Bound, PDB code: 7xob:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sars-Cov-2 Omicron Ba.2 Variant Spike Trimer with Two Mouse ACE2 Bound


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Omicron Ba.2 Variant Spike Trimer with Two Mouse ACE2 Bound within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn901 b:95.2 occ:1.00 OE2 D:GLU375 3.5 0.9 1.0 O D:PRO346 4.2 0.9 1.0 OE2 D:GLU402 4.4 0.8 1.0 NE2 D:HIS374 4.5 0.9 1.0 CD D:GLU375 4.7 0.9 1.0 OE1 D:GLU402 4.7 0.8 1.0 CD D:GLU402 4.9 0.8 1.0 CD2 D:HIS374 5.0 0.9 1.0

Zinc binding site 2 out of 2 in the Sars-Cov-2 Omicron Ba.2 Variant Spike Trimer with Two Mouse ACE2 Bound


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Cov-2 Omicron Ba.2 Variant Spike Trimer with Two Mouse ACE2 Bound within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn901 b:95.2 occ:1.00 OE2 E:GLU375 3.5 0.9 1.0 O E:PRO346 4.2 0.9 1.0 OE2 E:GLU402 4.4 0.8 1.0 NE2 E:HIS374 4.5 0.9 1.0 CD E:GLU375 4.7 0.9 1.0 OE1 E:GLU402 4.7 0.8 1.0 CD E:GLU402 4.9 0.8 1.0 CD2 E:HIS374 5.0 0.9 1.0

Y.Xu, C.Wu, X.Cao, C.Gu, H.Liu, M.Jiang, X.Wang, Q.Yuan, K.Wu, J.Liu, D.Wang, X.He, X.Wang, S.J.Deng, H.E.Xu, W.Yin. Structural and Biochemical Mechanism For Increased Infectivity and Immune Evasion of Omicron Ba.2 Variant Compared to Ba.1 and Their Possible Mouse Origins. Cell Res. V. 32 609 2022.
ISSN: ISSN 1001-0602
PubMed: 35641567
DOI: 10.1038/S41422-022-00672-4