Zinc in PDB 7xfg: uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1

Enzymatic activity of uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1

All present enzymatic activity of uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1:
2.3.1.48;

Zinc Binding Sites:

The binding sites of Zinc atom in the uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1 (pdb code 7xfg). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1, PDB code: 7xfg:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in 7xfg

Go back to Zinc Binding Sites List in 7xfg
Zinc binding site 1 out of 3 in the uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn501

b:0.0
occ:1.00
NE2 A:HIS49 2.1 0.0 1.0
SG A:CYS53 2.4 0.0 1.0
SG A:CYS64 2.4 0.0 1.0
SG A:CYS61 2.4 0.0 1.0
HB2 A:CYS53 3.0 0.0 1.0
CD2 A:HIS49 3.0 0.0 1.0
HB2 A:CYS64 3.0 0.0 1.0
CE1 A:HIS49 3.1 0.0 1.0
HD2 A:HIS49 3.2 0.0 1.0
CB A:CYS53 3.2 0.0 1.0
H A:CYS64 3.2 0.0 1.0
HB2 A:CYS61 3.2 0.0 1.0
CB A:CYS61 3.3 0.0 1.0
CB A:CYS64 3.3 0.0 1.0
HB3 A:CYS53 3.4 0.0 1.0
HE1 A:HIS49 3.5 0.0 1.0
HA A:LYS56 3.5 0.0 1.0
HB3 A:CYS61 3.5 0.0 1.0
HB A:ILE63 3.5 0.0 1.0
HG22 A:ILE63 3.7 0.0 1.0
HA A:THR50 3.7 0.0 1.0
N A:CYS64 3.9 0.0 1.0
HB3 A:LYS56 4.1 0.0 1.0
HB3 A:CYS64 4.1 0.0 1.0
CG A:HIS49 4.1 0.0 1.0
ND1 A:HIS49 4.2 0.0 1.0
CA A:CYS64 4.2 0.0 1.0
CA A:LYS56 4.4 0.0 1.0
CB A:ILE63 4.5 0.0 1.0
CG2 A:ILE63 4.5 0.0 1.0
CA A:CYS53 4.6 0.0 1.0
N A:LYS56 4.6 0.0 1.0
HA A:CYS64 4.6 0.0 1.0
CB A:LYS56 4.7 0.0 1.0
H A:LYS56 4.7 0.0 1.0
CA A:CYS61 4.7 0.0 1.0
CA A:THR50 4.8 0.0 1.0
HA A:CYS53 4.8 0.0 1.0
HG21 A:THR50 4.8 0.0 1.0
O A:HIS49 4.8 0.0 1.0
HG3 A:LYS56 4.8 0.0 1.0
HG23 A:ILE63 4.9 0.0 1.0
HB2 A:ARG55 4.9 0.0 1.0
HA A:CYS61 4.9 0.0 1.0
C A:ILE63 4.9 0.0 1.0
HD2 A:PRO62 5.0 0.0 1.0
H A:ILE63 5.0 0.0 1.0

Zinc binding site 2 out of 3 in 7xfg

Go back to Zinc Binding Sites List in 7xfg
Zinc binding site 2 out of 3 in the uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn502

b:0.0
occ:1.00
NE2 A:HIS26 2.1 0.0 1.0
SG A:CYS40 2.4 0.0 1.0
SG A:CYS35 2.4 0.0 1.0
SG A:CYS30 2.4 0.0 1.0
HB2 A:CYS40 3.0 0.0 1.0
HB3 A:CYS35 3.0 0.0 1.0
CD2 A:HIS26 3.0 0.0 1.0
CE1 A:HIS26 3.2 0.0 1.0
HB2 A:CYS30 3.2 0.0 1.0
HD2 A:HIS26 3.2 0.0 1.0
CB A:CYS40 3.2 0.0 1.0
CB A:CYS35 3.3 0.0 1.0
CB A:CYS30 3.3 0.0 1.0
HE1 A:HIS26 3.5 0.0 1.0
HB3 A:CYS40 3.7 0.0 1.0
HB3 A:CYS30 3.7 0.0 1.0
HB2 A:CYS35 3.8 0.0 1.0
HB3 A:LEU37 3.9 0.0 1.0
CG A:HIS26 4.2 0.0 1.0
ND1 A:HIS26 4.2 0.0 1.0
HB3 A:ASN32 4.3 0.0 1.0
O A:CYS35 4.3 0.0 1.0
HD11 A:LEU37 4.5 0.0 1.0
H A:LEU37 4.5 0.0 1.0
CA A:CYS40 4.6 0.0 1.0
CA A:CYS35 4.6 0.0 1.0
HB2 A:LEU37 4.6 0.0 1.0
HA A:CYS40 4.6 0.0 1.0
C A:CYS35 4.7 0.0 1.0
CA A:CYS30 4.7 0.0 1.0
HA A:ALA27 4.7 0.0 1.0
HA A:CYS30 4.8 0.0 1.0
CB A:LEU37 4.8 0.0 1.0
O A:ASN32 4.8 0.0 1.0
O A:HIS26 4.8 0.0 1.0

Zinc binding site 3 out of 3 in 7xfg

Go back to Zinc Binding Sites List in 7xfg
Zinc binding site 3 out of 3 in the uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of uc(Nmr) Solution Structures of P300 TAZ2 Domain in Complex with BRD4-Nut F1C Domain Binding Motif #1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn503

b:0.0
occ:1.00
NE2 A:HIS74 2.1 0.0 1.0
SG A:CYS83 2.3 0.0 1.0
SG A:CYS88 2.4 0.0 1.0
SG A:CYS78 2.4 0.0 1.0
CD2 A:HIS74 3.0 0.0 1.0
HB2 A:CYS83 3.1 0.0 1.0
CE1 A:HIS74 3.1 0.0 1.0
HD2 A:HIS74 3.2 0.0 1.0
HB2 A:CYS78 3.2 0.0 1.0
CB A:CYS83 3.2 0.0 1.0
HB A:VAL85 3.3 0.0 1.0
CB A:CYS78 3.3 0.0 1.0
HB2 A:CYS88 3.3 0.0 1.0
CB A:CYS88 3.3 0.0 1.0
HB3 A:CYS88 3.3 0.0 1.0
HB3 A:CYS78 3.4 0.0 1.0
HE1 A:HIS74 3.4 0.0 1.0
HB3 A:CYS83 3.4 0.0 1.0
HG23 A:VAL85 4.0 0.0 1.0
CG A:HIS74 4.1 0.0 1.0
HA A:ALA75 4.1 0.0 1.0
ND1 A:HIS74 4.1 0.0 1.0
CB A:VAL85 4.2 0.0 1.0
HG21 A:VAL85 4.4 0.0 1.0
HB2 A:GLU80 4.4 0.0 1.0
CG2 A:VAL85 4.4 0.0 1.0
HG13 A:VAL85 4.5 0.0 1.0
H A:VAL85 4.5 0.0 1.0
HD23 A:LEU89 4.5 0.0 1.0
HD2 A:PRO84 4.6 0.0 1.0
HG2 A:LYS92 4.6 0.0 1.0
CA A:CYS83 4.7 0.0 1.0
CA A:CYS88 4.7 0.0 1.0
CA A:CYS78 4.7 0.0 1.0
HD22 A:LEU89 4.7 0.0 1.0
O A:HIS74 4.8 0.0 1.0
OE2 A:GLU80 4.8 0.0 1.0
O A:GLU80 4.9 0.0 1.0
HG3 A:LYS92 4.9 0.0 1.0
HA A:CYS83 4.9 0.0 1.0
CG1 A:VAL85 4.9 0.0 1.0
HA A:CYS78 5.0 0.0 1.0

Reference:

D.Yu, L.Zeng, M.-M.Zhou. Structural Mechanism of BRD4-Nut Fusion Protein in P300-Activated Hyperacetylation To Be Published.
Page generated: Wed Apr 26 00:30:10 2023

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy