Zinc in PDB 7xcp: Cryo-Em Structure of Omicron Rbd Complexed with ACE2 and 304 Fab

The binding sites of Zinc atom in the Cryo-Em Structure of Omicron Rbd Complexed with ACE2 and 304 Fab (pdb code 7xcp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Omicron Rbd Complexed with ACE2 and 304 Fab, PDB code: 7xcp:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Omicron Rbd Complexed with ACE2 and 304 Fab


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Omicron Rbd Complexed with ACE2 and 304 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn704 b:46.7 occ:1.00 OE2 A:GLU402 2.2 27.6 1.0 NE2 A:HIS378 2.3 27.6 1.0 NE2 A:HIS374 2.3 27.6 1.0 CD A:GLU402 2.9 27.6 1.0 CD2 A:HIS378 2.9 27.6 1.0 OE1 A:GLU402 3.1 27.6 1.0 CD2 A:HIS374 3.1 27.6 1.0 CE1 A:HIS378 3.1 27.6 1.0 CE1 A:HIS374 3.4 27.6 1.0 OE2 A:GLU375 3.8 27.6 1.0 CG A:HIS378 3.8 27.6 1.0 ND1 A:HIS378 3.9 27.6 1.0 CG A:GLU402 4.2 27.6 1.0 OE1 A:GLU375 4.2 27.6 1.0 CG A:HIS374 4.3 27.6 1.0 CD A:GLU375 4.4 27.6 1.0 ND1 A:HIS374 4.4 27.6 1.0

Z.Zhao, J.Zhou, M.Tian, M.Huang, S.Liu, Y.Xie, P.Han, C.Bai, P.Han, A.Zheng, L.Fu, Y.Gao, Q.Peng, Y.Li, Y.Chai, Z.Zhang, X.Zhao, H.Song, J.Qi, Q.Wang, P.Wang, G.F.Gao. Omicron Sars-Cov-2 Mutations Stabilize Spike Up-Rbd Conformation and Lead to A Non-Rbm-Binding Monoclonal Antibody Escape Nat Commun V. 13 4958 2022.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-022-32665-7