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Zinc in PDB 7xbb: Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 23AEnzymatic activity of Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 23A
All present enzymatic activity of Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 23A:
3.1.4.53; Protein crystallography data
The structure of Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 23A, PDB code: 7xbb
was solved by
Y.-Y.Huang,
H.-B.Luo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7xbb:
The structure of Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 23A also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 23A
(pdb code 7xbb). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 23A, PDB code: 7xbb: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 7xbbGo back to Zinc Binding Sites List in 7xbb
Zinc binding site 1 out
of 2 in the Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 23A
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 7xbbGo back to Zinc Binding Sites List in 7xbb
Zinc binding site 2 out
of 2 in the Crystal Structure of PDE4D Catalytic Domain Complexed with Compound 23A
Mono view Stereo pair view
Reference:
F.Zhou,
Y.Huang,
L.Liu,
Z.Song,
K.Q.Hou,
Y.Yang,
H.B.Luo,
Y.Y.Huang,
X.F.Xiong.
Structure-Based Optimization of Toddacoumalone As Highly Potent and Selective PDE4 Inhibitors with Anti-Inflammatory Effects. Biochem Pharmacol V. 202 15123 2022.
Page generated: Sat Apr 8 05:51:15 2023
ISSN: ISSN 1873-2968 PubMed: 35688178 DOI: 10.1016/J.BCP.2022.115123 |
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