Zinc in PDB 7wwy: M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris)

All present enzymatic activity of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris):
1.15.1.1;

The structure of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris), PDB code: 7wwy was solved by S.Narikiyo, Y.Furukawa, M.Akutsu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.71 / 1.50
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	50.643, 50.643, 282.12, 90, 90, 90
R / Rfree (%)	25.6 / 28.7

The structure of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) also contains other interesting chemical elements:

Copper

(Cu)

2 atoms

The binding sites of Zinc atom in the M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) (pdb code 7wwy). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris), PDB code: 7wwy:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:17.5 occ:1.00 OD1 A:ASP83 2.0 17.4 1.0 ND1 A:HIS80 2.0 16.2 1.0 ND1 A:HIS63 2.0 15.4 1.0 ND1 A:HIS71 2.1 17.2 1.0 CG A:ASP83 2.8 16.0 1.0 CE1 A:HIS71 2.9 14.1 1.0 OD2 A:ASP83 2.9 17.0 1.0 CE1 A:HIS80 2.9 14.7 1.0 CE1 A:HIS63 3.0 18.7 1.0 CG A:HIS63 3.0 16.5 1.0 CG A:HIS80 3.1 18.1 1.0 CG A:HIS71 3.2 15.1 1.0 CB A:HIS63 3.4 16.1 1.0 CB A:HIS80 3.6 18.2 1.0 CB A:HIS71 3.6 16.7 1.0 O A:GLN136 3.8 16.6 1.0 CA A:HIS71 3.9 16.1 1.0 NE2 A:HIS71 4.1 14.7 1.0 NE2 A:HIS80 4.1 18.2 1.0 NE2 A:HIS63 4.1 20.4 1.0 CD2 A:HIS63 4.2 19.2 1.0 CB A:ASP83 4.2 16.2 1.0 CD2 A:HIS80 4.2 15.6 1.0 CD2 A:HIS71 4.2 14.7 1.0 N A:HIS80 4.7 18.1 1.0 CA A:ASP83 4.7 16.8 1.0 C A:GLN136 4.7 17.6 1.0 N A:GLY72 4.8 15.7 1.0 CA A:HIS80 4.8 17.4 1.0 O A:HOH401 4.8 19.8 1.0 CD2 A:HIS46 4.9 19.1 1.0 CA A:HIS63 4.9 15.9 1.0 N A:HIS71 4.9 16.1 1.0 C A:HIS71 4.9 17.1 1.0 N A:ASP83 5.0 15.5 1.0

Zinc binding site 2 out of 2 in the M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of M117L Variant of Cu/Zn-Superoxide Dismutase From Dog (Canis Familiaris) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:35.0 occ:1.00 ND1 B:HIS63 1.8 33.4 1.0 ND1 B:HIS80 2.0 30.7 1.0 OD1 B:ASP83 2.0 33.2 1.0 ND1 B:HIS71 2.1 35.4 1.0 CE1 B:HIS63 2.8 33.4 1.0 CG B:HIS63 2.9 34.7 1.0 CG B:ASP83 2.9 39.1 1.0 CE1 B:HIS80 2.9 35.4 1.0 CE1 B:HIS71 2.9 38.9 1.0 CG B:HIS80 3.0 31.4 1.0 OD2 B:ASP83 3.2 36.3 1.0 CG B:HIS71 3.2 40.9 1.0 CB B:HIS63 3.3 39.4 1.0 CB B:HIS80 3.4 35.4 1.0 CB B:HIS71 3.6 35.8 1.0 O B:GLN136 3.8 41.5 1.0 CA B:HIS71 3.9 36.9 1.0 NE2 B:HIS63 4.0 32.3 1.0 NE2 B:HIS80 4.0 34.0 1.0 CD2 B:HIS63 4.0 32.8 1.0 CD2 B:HIS80 4.0 32.0 1.0 NE2 B:HIS71 4.1 38.5 1.0 CD2 B:HIS71 4.2 41.0 1.0 CB B:ASP83 4.3 37.4 1.0 O B:HOH351 4.6 41.2 1.0 CD2 B:HIS46 4.7 33.3 1.0 N B:GLY72 4.7 40.6 1.0 CA B:HIS80 4.7 35.5 1.0 N B:HIS80 4.7 34.9 1.0 CA B:ASP83 4.7 33.3 1.0 C B:HIS71 4.8 43.8 1.0 CA B:HIS63 4.8 38.3 1.0 C B:GLN136 4.9 44.0 1.0 N B:HIS71 4.9 35.8 1.0 O B:GLY72 5.0 41.0 1.0 N B:ASP83 5.0 35.4 1.0

S.Narikiyo, Y.Furukawa, M.Akutsu. Crystal Structure of Dog Superoxide Dismutase To Be Published.