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Zinc in PDB 7w3r: USP34 Catalytic Domain

Enzymatic activity of USP34 Catalytic Domain

All present enzymatic activity of USP34 Catalytic Domain:
3.4.19.12;

Protein crystallography data

The structure of USP34 Catalytic Domain, PDB code: 7w3r was solved by G.L.Xu, Z.H.Ming, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.01 / 1.92
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 50.12, 128.06, 64.4, 90, 93.49, 90
R / Rfree (%) 22.6 / 26.2

Zinc Binding Sites:

The binding sites of Zinc atom in the USP34 Catalytic Domain (pdb code 7w3r). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the USP34 Catalytic Domain, PDB code: 7w3r:

Zinc binding site 1 out of 1 in 7w3r

Go back to Zinc Binding Sites List in 7w3r
Zinc binding site 1 out of 1 in the USP34 Catalytic Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of USP34 Catalytic Domain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2301

b:41.4
occ:1.00
SG A:CYS2065 2.1 47.2 1.0
ND1 A:HIS2020 2.1 45.5 1.0
SG A:CYS2062 2.3 40.4 1.0
SG A:CYS2018 2.3 43.0 1.0
CE1 A:HIS2020 3.1 47.6 1.0
CB A:CYS2062 3.1 51.9 1.0
CG A:HIS2020 3.2 42.0 1.0
CB A:CYS2018 3.2 43.6 1.0
CB A:HIS2020 3.5 40.9 1.0
CB A:CYS2065 3.7 47.7 1.0
N A:CYS2065 3.8 53.1 1.0
NE2 A:HIS2020 4.2 44.0 1.0
CD2 A:HIS2020 4.3 43.8 1.0
CA A:CYS2065 4.3 51.7 1.0
N A:HIS2020 4.3 49.8 1.0
CB A:HIS2064 4.4 46.0 1.0
CA A:HIS2020 4.6 46.4 1.0
CA A:CYS2062 4.6 45.3 1.0
CA A:CYS2018 4.6 43.7 1.0
C A:HIS2064 4.7 50.6 1.0
O A:HOH2509 4.9 58.4 1.0
N A:GLU2019 4.9 52.7 1.0
CA A:HIS2064 4.9 44.7 1.0
N A:HIS2064 4.9 41.3 1.0
C A:CYS2018 5.0 40.2 1.0

Reference:

G.Xu, H.Su, L.Lu, X.Liu, L.Zhao, B.Tang, Z.Ming. Structural Insights Into the Catalytic Mechanism and Ubiquitin Recognition of USP34. J.Mol.Biol. V. 434 67634 2022.
ISSN: ESSN 1089-8638
PubMed: 35588869
DOI: 10.1016/J.JMB.2022.167634
Page generated: Wed Oct 30 13:37:25 2024

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