Zinc in PDB 7w1q: The Structure of the Arabidopsis Thaliana Guanosine Deaminase Mutant E82Q Complexed with 2'-O-Methylguanosine

All present enzymatic activity of The Structure of the Arabidopsis Thaliana Guanosine Deaminase Mutant E82Q Complexed with 2'-O-Methylguanosine:
3.5.4.15;

The structure of The Structure of the Arabidopsis Thaliana Guanosine Deaminase Mutant E82Q Complexed with 2'-O-Methylguanosine, PDB code: 7w1q was solved by W.Xie, Q.Jia, H.Zeng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.69 / 2.30
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	119.244, 119.244, 39.01, 90, 90, 120
R / Rfree (%)	21.1 / 23.8

The binding sites of Zinc atom in the The Structure of the Arabidopsis Thaliana Guanosine Deaminase Mutant E82Q Complexed with 2'-O-Methylguanosine (pdb code 7w1q). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Structure of the Arabidopsis Thaliana Guanosine Deaminase Mutant E82Q Complexed with 2'-O-Methylguanosine, PDB code: 7w1q:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Structure of the Arabidopsis Thaliana Guanosine Deaminase Mutant E82Q Complexed with 2'-O-Methylguanosine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Structure of the Arabidopsis Thaliana Guanosine Deaminase Mutant E82Q Complexed with 2'-O-Methylguanosine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:18.4 occ:1.00 ND1 A:HIS80 2.0 21.4 1.0 O A:HOH334 2.2 14.2 1.0 SG A:CYS113 2.2 18.0 1.0 SG A:CYS110 2.3 19.6 1.0 CE1 A:HIS80 2.9 20.3 1.0 CG A:HIS80 3.1 20.2 1.0 CB A:CYS113 3.2 19.4 1.0 CB A:CYS110 3.3 17.3 1.0 CB A:HIS80 3.6 16.6 1.0 N A:CYS110 3.8 20.5 1.0 N A:CYS113 3.9 16.6 1.0 CE A:MET112 4.0 18.2 1.0 NE2 A:HIS80 4.1 21.5 1.0 CA A:CYS110 4.1 17.3 1.0 OE1 A:GLN82 4.1 23.2 1.0 CA A:CYS113 4.2 16.0 1.0 CD2 A:HIS80 4.2 22.4 1.0 C6 A:OMG202 4.4 23.9 1.0 C5 A:OMG202 4.4 26.1 1.0 N1 A:OMG202 4.5 23.9 1.0 C4 A:OMG202 4.5 28.9 1.0 N3 A:OMG202 4.5 29.6 1.0 C2 A:OMG202 4.5 26.9 1.0 C A:CYS110 4.7 17.8 1.0 O A:CYS110 4.8 16.6 1.0 C A:PRO109 4.9 19.5 1.0 O6 A:OMG202 4.9 19.5 1.0 CB A:MET112 5.0 17.1 1.0 C A:MET112 5.0 16.9 1.0

Zinc binding site 2 out of 2 in the The Structure of the Arabidopsis Thaliana Guanosine Deaminase Mutant E82Q Complexed with 2'-O-Methylguanosine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Structure of the Arabidopsis Thaliana Guanosine Deaminase Mutant E82Q Complexed with 2'-O-Methylguanosine within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn201 b:19.5 occ:1.00 O D:HOH316 1.9 20.3 1.0 ND1 D:HIS80 2.0 24.3 1.0 SG D:CYS110 2.2 22.4 1.0 SG D:CYS113 2.3 17.8 1.0 CE1 D:HIS80 2.9 25.6 1.0 CB D:CYS110 3.1 22.4 1.0 CG D:HIS80 3.1 22.3 1.0 CB D:CYS113 3.3 18.9 1.0 CB D:HIS80 3.6 19.8 1.0 N D:CYS110 3.7 15.6 1.0 N D:CYS113 3.9 17.3 1.0 CA D:CYS110 4.0 20.2 1.0 NE2 D:HIS80 4.1 22.2 1.0 C2 D:OMG202 4.2 36.4 1.0 CA D:CYS113 4.2 18.7 1.0 NE2 D:GLN82 4.2 19.8 1.0 N1 D:OMG202 4.2 29.1 1.0 CD2 D:HIS80 4.2 21.7 1.0 N3 D:OMG202 4.2 45.9 1.0 C6 D:OMG202 4.3 27.0 1.0 C4 D:OMG202 4.3 37.4 1.0 C5 D:OMG202 4.3 30.5 1.0 CE D:MET112 4.4 17.6 1.0 C D:CYS110 4.6 20.1 1.0 O D:CYS110 4.7 18.5 1.0 N2 D:OMG202 4.8 27.0 1.0 C D:PRO109 4.8 19.4 1.0 O6 D:OMG202 4.8 26.5 1.0 N9 D:OMG202 5.0 42.6 1.0 CB D:MET112 5.0 14.1 1.0 N7 D:OMG202 5.0 33.0 1.0

W.Xie, Q.Jia, H.Zeng. Catalysis Asymmetry of Guanosine Deaminase Revealed By Cocrystal Structures To Be Published.