Zinc in PDB 7to2: Cryo-Em Structure of Rig-I Bound to the Internal Sites of P3SLR30 (+Atp)

All present enzymatic activity of Cryo-Em Structure of Rig-I Bound to the Internal Sites of P3SLR30 (+Atp):
3.6.4.13;

The structure of Cryo-Em Structure of Rig-I Bound to the Internal Sites of P3SLR30 (+Atp) also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Cryo-Em Structure of Rig-I Bound to the Internal Sites of P3SLR30 (+Atp) (pdb code 7to2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Rig-I Bound to the Internal Sites of P3SLR30 (+Atp), PDB code: 7to2:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Rig-I Bound to the Internal Sites of P3SLR30 (+Atp)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Rig-I Bound to the Internal Sites of P3SLR30 (+Atp) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:23.5 occ:1.00 SG A:CYS810 2.4 38.5 1.0 SG A:CYS869 2.5 66.5 1.0 SG A:CYS864 2.5 65.7 1.0 SG A:CYS813 2.5 48.4 1.0 CB A:CYS864 2.7 63.9 1.0 CB A:CYS810 3.2 38.9 1.0 CB A:CYS869 3.6 68.0 1.0 CB A:CYS813 3.8 48.5 1.0 CZ2 A:TRP873 3.8 39.8 1.0 NE1 A:TRP873 3.9 39.4 1.0 N A:CYS813 4.2 45.3 1.0 CE2 A:TRP873 4.2 39.6 1.0 CA A:CYS864 4.2 63.4 1.0 CB A:HIS871 4.3 46.0 1.0 CA A:CYS813 4.5 47.6 1.0 CA A:CYS810 4.7 39.0 1.0 N A:LYS814 5.0 51.3 1.0 CH2 A:TRP873 5.0 39.7 1.0 CA A:CYS869 5.0 68.4 1.0

W.Wang, A.M.Pyle. The Rig-I Receptor Adopts Two Different Conformations For Distinguishing Host From Viral Rna Ligands. Mol.Cell V. 82 4131 2022.
ISSN: ISSN 1097-2765
PubMed: 36272408
DOI: 10.1016/J.MOLCEL.2022.09.029