Zinc in PDB 7syv: Structure of the Wt Ires EIF5B-Containing Pre-48S Initiation Complex, Open Conformation. Structure 14(Wt)

The structure of Structure of the Wt Ires EIF5B-Containing Pre-48S Initiation Complex, Open Conformation. Structure 14(Wt) also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Sodium	(Na)	1 atom

The binding sites of Zinc atom in the Structure of the Wt Ires EIF5B-Containing Pre-48S Initiation Complex, Open Conformation. Structure 14(Wt) (pdb code 7syv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Wt Ires EIF5B-Containing Pre-48S Initiation Complex, Open Conformation. Structure 14(Wt), PDB code: 7syv:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of the Wt Ires EIF5B-Containing Pre-48S Initiation Complex, Open Conformation. Structure 14(Wt)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Wt Ires EIF5B-Containing Pre-48S Initiation Complex, Open Conformation. Structure 14(Wt) within 5.0Å range: probe atom residue distance (Å) B Occ b:Zn201 b:185.0 occ:1.00 CB b:CYS26 2.1 155.0 1.0 SG b:CYS74 2.2 147.0 1.0 SG b:CYS26 2.2 155.0 1.0 SG b:CYS77 2.3 145.1 1.0 SG b:CYS23 2.3 147.1 1.0 N b:CYS26 2.5 155.0 1.0 CA b:CYS26 2.8 155.0 1.0 CB b:CYS23 3.2 147.1 1.0 CB b:CYS77 3.4 145.1 1.0 C b:CYS26 3.7 155.0 1.0 C b:ASN25 3.7 147.8 1.0 CB b:CYS74 3.8 147.0 1.0 O b:CYS26 4.2 155.0 1.0 N b:ASN25 4.2 147.8 1.0 CB b:ASN25 4.2 147.8 1.0 CA b:ASN25 4.2 147.8 1.0 N b:CYS74 4.3 147.0 1.0 N b:ALA27 4.4 145.2 1.0 CA b:CYS23 4.6 147.1 1.0 CA b:CYS74 4.6 147.0 1.0 N b:THR24 4.6 145.2 1.0 O b:ASN25 4.7 147.8 1.0 CA b:CYS77 4.8 145.1 1.0 C b:CYS23 4.8 147.1 1.0

Zinc binding site 2 out of 2 in the Structure of the Wt Ires EIF5B-Containing Pre-48S Initiation Complex, Open Conformation. Structure 14(Wt)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Wt Ires EIF5B-Containing Pre-48S Initiation Complex, Open Conformation. Structure 14(Wt) within 5.0Å range: probe atom residue distance (Å) B Occ g:Zn200 b:510.3 occ:1.00 SG g:CYS121 2.3 483.4 1.0 SG g:CYS144 2.3 494.3 1.0 SG g:CYS126 2.3 486.6 1.0 SG g:CYS141 2.3 487.9 1.0 CB g:CYS141 2.6 487.9 1.0 CB g:CYS144 2.6 494.3 1.0 CB g:CYS121 3.1 483.4 1.0 CB g:CYS126 3.8 486.6 1.0 CA g:CYS141 3.8 487.9 1.0 CA g:CYS144 3.9 494.3 1.0 N g:CYS144 4.0 494.3 1.0 N g:GLY142 4.1 487.9 1.0 CA g:CYS121 4.5 483.4 1.0 C g:CYS141 4.5 487.9 1.0 N g:CYS145 4.5 493.0 1.0 C g:CYS144 4.6 494.3 1.0 OG g:SER123 4.9 485.6 1.0 N g:CYS141 4.9 487.9 1.0 N g:LEU146 5.0 490.9 1.0 OH g:TYR148 5.0 481.8 1.0

Z.P.Brown, I.S.Abaeva, S.De, C.U.T.Hellen, T.V.Pestova, J.Frank. Molecular Architecture of 40S Translation Initiation Complexes on the Hepatitis C Virus Ires. Embo J. V. 41 10581 2022.
ISSN: ESSN 1460-2075
PubMed: 35822879
DOI: 10.15252/EMBJ.2022110581