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Zinc in PDB 7syh: Structure of the Hcv Ires Binding to the 40S Ribosomal Subunit, Closed Conformation. Structure 2(Delta Dii)

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of the Hcv Ires Binding to the 40S Ribosomal Subunit, Closed Conformation. Structure 2(Delta Dii) (pdb code 7syh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Hcv Ires Binding to the 40S Ribosomal Subunit, Closed Conformation. Structure 2(Delta Dii), PDB code: 7syh:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 7syh

Go back to Zinc Binding Sites List in 7syh
Zinc binding site 1 out of 2 in the Structure of the Hcv Ires Binding to the 40S Ribosomal Subunit, Closed Conformation. Structure 2(Delta Dii)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Hcv Ires Binding to the 40S Ribosomal Subunit, Closed Conformation. Structure 2(Delta Dii) within 5.0Å range:
probe atom residue distance (Å) B Occ
b:Zn201

b:90.7
occ:1.00
SG b:CYS77 2.2 60.1 1.0
SG b:CYS23 2.2 68.2 1.0
SG b:CYS74 2.2 59.0 1.0
SG b:CYS26 2.2 66.9 1.0
CB b:CYS77 2.4 60.1 1.0
CB b:CYS74 3.3 59.0 1.0
CB b:CYS23 3.3 68.2 1.0
N b:CYS74 3.4 59.0 1.0
CB b:CYS26 3.7 66.9 1.0
N b:CYS26 3.8 66.9 1.0
CA b:CYS77 3.8 60.1 1.0
CA b:CYS74 3.8 59.0 1.0
N b:CYS77 4.2 60.1 1.0
CA b:CYS26 4.3 66.9 1.0
O b:CYS74 4.4 59.0 1.0
C b:CYS74 4.4 59.0 1.0
C b:TYR73 4.5 62.3 1.0
CB b:ASN25 4.5 64.7 1.0
C b:ASN25 4.6 64.7 1.0
N b:ASN25 4.6 64.7 1.0
CA b:TYR73 4.7 62.3 1.0
C b:CYS77 4.7 60.1 1.0
CA b:CYS23 4.7 68.2 1.0
CA b:ASN25 4.8 64.7 1.0
C b:CYS26 4.9 66.9 1.0
N b:THR24 4.9 68.2 1.0

Zinc binding site 2 out of 2 in 7syh

Go back to Zinc Binding Sites List in 7syh
Zinc binding site 2 out of 2 in the Structure of the Hcv Ires Binding to the 40S Ribosomal Subunit, Closed Conformation. Structure 2(Delta Dii)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Hcv Ires Binding to the 40S Ribosomal Subunit, Closed Conformation. Structure 2(Delta Dii) within 5.0Å range:
probe atom residue distance (Å) B Occ
g:Zn200

b:299.1
occ:1.00
SG g:CYS141 2.2 271.9 1.0
SG g:CYS126 2.2 261.3 1.0
SG g:CYS144 2.3 263.3 1.0
SG g:CYS121 2.3 258.0 1.0
CB g:CYS144 3.0 263.3 1.0
CB g:CYS126 3.3 261.3 1.0
CB g:CYS121 3.5 258.0 1.0
N g:CYS144 3.7 263.3 1.0
CA g:CYS144 4.0 263.3 1.0
CB g:CYS141 4.0 271.9 1.0
CB g:SER123 4.1 260.2 1.0
N g:CYS126 4.2 261.3 1.0
CA g:CYS126 4.4 261.3 1.0
O g:SER123 4.7 260.2 1.0
OG g:SER123 4.7 260.2 1.0
N g:LYS143 4.8 264.9 1.0
C g:LYS143 4.9 264.9 1.0
CA g:CYS121 4.9 258.0 1.0
CA g:SER123 5.0 260.2 1.0
N g:SER123 5.0 260.2 1.0
CA g:CYS141 5.0 271.9 1.0
N g:GLY142 5.0 267.6 1.0

Reference:

Z.P.Brown, I.S.Abaeva, S.De, C.U.T.Hellen, T.V.Pestova, J.Frank. Molecular Architecture of 40S Initiation Complexes on the Hepatitis C Virus Ires: From Ribosomal Attachment to EIF5B-Mediated Reorientation of Initiator Trna To Be Published.
Page generated: Sat Apr 8 03:15:21 2023

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