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Atomistry » Zinc » PDB 7s6m-7spy » 7sfc » |
Zinc in PDB 7sfc: Human DNMT1(729-1600) Bound to Zebularine-Containing 12MER Dsdna and Inhibitor GSK3735967AEnzymatic activity of Human DNMT1(729-1600) Bound to Zebularine-Containing 12MER Dsdna and Inhibitor GSK3735967A
All present enzymatic activity of Human DNMT1(729-1600) Bound to Zebularine-Containing 12MER Dsdna and Inhibitor GSK3735967A:
2.1.1.37; Protein crystallography data
The structure of Human DNMT1(729-1600) Bound to Zebularine-Containing 12MER Dsdna and Inhibitor GSK3735967A, PDB code: 7sfc
was solved by
J.R.Horton,
S.Pathuri,
X.Cheng,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human DNMT1(729-1600) Bound to Zebularine-Containing 12MER Dsdna and Inhibitor GSK3735967A
(pdb code 7sfc). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Human DNMT1(729-1600) Bound to Zebularine-Containing 12MER Dsdna and Inhibitor GSK3735967A, PDB code: 7sfc: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 7sfcGo back to![]() ![]()
Zinc binding site 1 out
of 2 in the Human DNMT1(729-1600) Bound to Zebularine-Containing 12MER Dsdna and Inhibitor GSK3735967A
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 7sfcGo back to![]() ![]()
Zinc binding site 2 out
of 2 in the Human DNMT1(729-1600) Bound to Zebularine-Containing 12MER Dsdna and Inhibitor GSK3735967A
![]() Mono view ![]() Stereo pair view
Reference:
J.R.Horton,
S.Pathuri,
K.Wong,
R.Ren,
L.Rueda,
D.T.Fosbenner,
D.A.Heerding,
M.T.Mccabe,
M.B.Pappalardi,
X.Zhang,
B.W.King,
X.Cheng.
Structural Characterization of Dicyanopyridine Containing DNMT1-Selective, Non-Nucleoside Inhibitors. Structure V. 30 793 2022.
Page generated: Sat Apr 8 03:07:02 2023
ISSN: ISSN 0969-2126 PubMed: 35395178 DOI: 10.1016/J.STR.2022.03.009 |
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