Zinc in PDB 7rw6: BORF2-APOBEC3BCTD Complex

All present enzymatic activity of BORF2-APOBEC3BCTD Complex:
1.17.4.1; 3.5.4.38;

The binding sites of Zinc atom in the BORF2-APOBEC3BCTD Complex (pdb code 7rw6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the BORF2-APOBEC3BCTD Complex, PDB code: 7rw6:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the BORF2-APOBEC3BCTD Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of BORF2-APOBEC3BCTD Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:102.6 occ:1.00 ND1 B:HIS253 2.0 70.5 1.0 SG B:CYS284 2.1 68.8 1.0 SG B:CYS289 2.4 94.7 1.0 CE1 B:HIS253 2.8 72.2 1.0 CB B:CYS289 3.0 72.9 1.0 CG B:HIS253 3.2 66.8 1.0 OE2 B:GLU255 3.2 79.5 1.0 CB B:CYS284 3.5 67.4 1.0 CB B:HIS253 3.7 67.9 1.0 CD B:GLU255 3.8 80.6 1.0 N B:CYS284 3.8 63.8 1.0 NE2 B:HIS253 4.0 73.8 1.0 OE1 B:GLU255 4.0 82.5 1.0 CA B:CYS284 4.2 61.4 1.0 CD2 B:HIS253 4.2 69.3 1.0 CA B:CYS289 4.5 74.8 1.0 O B:CYS284 4.6 72.6 1.0 C B:CYS284 4.7 64.3 1.0 CG B:GLU255 4.8 77.6 1.0 N B:CYS289 4.8 79.0 1.0 CA B:HIS253 4.8 71.7 1.0 CB B:TRP287 4.9 71.0 1.0 C B:PRO283 4.9 55.2 1.0

Zinc binding site 2 out of 2 in the BORF2-APOBEC3BCTD Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of BORF2-APOBEC3BCTD Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn501 b:105.7 occ:1.00 ND1 D:HIS253 1.8 76.8 1.0 SG D:CYS284 2.0 73.6 1.0 SG D:CYS289 2.4 97.1 1.0 CE1 D:HIS253 2.6 75.6 1.0 CG D:HIS253 3.0 75.8 1.0 OE2 D:GLU255 3.1 80.6 1.0 CB D:CYS289 3.3 76.9 1.0 CB D:HIS253 3.6 76.0 1.0 CB D:CYS284 3.7 69.4 1.0 CD D:GLU255 3.8 81.0 1.0 NE2 D:HIS253 3.8 77.5 1.0 N D:CYS284 4.0 65.9 1.0 CD2 D:HIS253 4.0 75.2 1.0 OE1 D:GLU255 4.0 82.6 1.0 CA D:CYS284 4.4 65.1 1.0 CB D:TRP287 4.6 79.7 1.0 CA D:CYS289 4.6 79.0 1.0 CA D:HIS253 4.8 76.7 1.0 O D:CYS284 4.8 78.6 1.0 N D:CYS289 4.8 82.5 1.0 C D:CYS284 4.9 68.5 1.0 CG D:GLU255 4.9 77.8 1.0

N.M.Shaban, R.Yan, K.Shi, S.N.Moraes, A.Z.Cheng, M.A.Carpenter, J.S.Mclellan, Z.Yu, R.S.Harris. Cryo-Em Structure of the Ebv Ribonucleotide Reductase BORF2 and Mechanism of APOBEC3B Inhibition. Sci Adv V. 8 M2827 2022.
ISSN: ESSN 2375-2548
PubMed: 35476445
DOI: 10.1126/SCIADV.ABM2827