Zinc in PDB 7rhq: Cryo-Em Structure of Xenopus Patched-1 in Complex with GAS1 and Sonic Hedgehog

The structure of Cryo-Em Structure of Xenopus Patched-1 in Complex with GAS1 and Sonic Hedgehog also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Zinc atom in the Cryo-Em Structure of Xenopus Patched-1 in Complex with GAS1 and Sonic Hedgehog (pdb code 7rhq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Xenopus Patched-1 in Complex with GAS1 and Sonic Hedgehog, PDB code: 7rhq:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Xenopus Patched-1 in Complex with GAS1 and Sonic Hedgehog


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Xenopus Patched-1 in Complex with GAS1 and Sonic Hedgehog within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn202 b:171.3 occ:1.00 OD1 C:ASP147 2.2 148.2 1.0 NE2 C:HIS140 2.2 151.0 1.0 ND1 C:HIS182 2.3 150.0 1.0 OD2 C:ASP147 2.3 148.2 1.0 NE2 C:HIS134 2.4 156.9 1.0 CG C:ASP147 2.5 148.2 1.0 CE1 C:HIS182 2.9 150.0 1.0 CE1 C:HIS140 2.9 151.0 1.0 CD2 C:HIS134 2.9 156.9 1.0 CE1 C:HIS134 3.4 156.9 1.0 CG C:HIS182 3.4 150.0 1.0 CD2 C:HIS140 3.4 151.0 1.0 CE1 C:HIS180 3.7 151.3 1.0 CB C:HIS182 3.9 150.0 1.0 NE2 C:HIS182 4.0 150.0 1.0 CG C:HIS134 4.0 156.9 1.0 CB C:ASP147 4.1 148.2 1.0 ND1 C:HIS180 4.1 151.3 1.0 ND1 C:HIS140 4.2 151.0 1.0 ND1 C:HIS134 4.2 156.9 1.0 CD2 C:HIS182 4.3 150.0 1.0 CG C:HIS140 4.4 151.0 1.0 CA C:HIS182 4.6 150.0 1.0 NE2 C:HIS180 4.7 151.3 1.0 CA C:ASP147 4.8 148.2 1.0 N C:ASP147 5.0 148.2 1.0

P.Huang, B.M.Wierbowski, T.Lian, C.Chan, S.Garcia-Linares, J.Jiang, A.Salic. Structural Basis For Catalyzed Assembly of the Sonic Hedgehog-PATCHED1 Signaling Complex. Dev.Cell V. 57 670 2022.
ISSN: ISSN 1534-5807
PubMed: 35231446
DOI: 10.1016/J.DEVCEL.2022.02.008