Zinc in PDB 7r10: Dissociated S1 Domain of Alpha Variant Sars-Cov-2 Spike Bound to ACE2

All present enzymatic activity of Dissociated S1 Domain of Alpha Variant Sars-Cov-2 Spike Bound to ACE2:
3.4.17.23;

The binding sites of Zinc atom in the Dissociated S1 Domain of Alpha Variant Sars-Cov-2 Spike Bound to ACE2 (pdb code 7r10). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Dissociated S1 Domain of Alpha Variant Sars-Cov-2 Spike Bound to ACE2, PDB code: 7r10:

Zinc binding site 1 out of 1 in the Dissociated S1 Domain of Alpha Variant Sars-Cov-2 Spike Bound to ACE2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Dissociated S1 Domain of Alpha Variant Sars-Cov-2 Spike Bound to ACE2 within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn901 b:117.4 occ:1.00 OE2 D:GLU402 2.1 69.6 1.0 NE2 D:HIS378 2.3 60.6 1.0 NE2 D:HIS374 2.3 66.8 1.0 CD2 D:HIS374 2.7 66.8 1.0 CD2 D:HIS378 2.9 60.6 1.0 CD D:GLU402 3.1 69.6 1.0 CE1 D:HIS378 3.5 60.6 1.0 OE1 D:GLU402 3.6 69.6 1.0 CE1 D:HIS374 3.6 66.8 1.0 CG D:HIS374 4.0 66.8 1.0 CG D:HIS378 4.1 60.6 1.0 ND1 D:HIS378 4.4 60.6 1.0 CG D:GLU402 4.4 69.6 1.0 ND1 D:HIS374 4.4 66.8 1.0 OE2 D:GLU375 4.6 73.7 1.0 OE1 D:GLU375 4.7 73.7 1.0 CD D:GLU375 4.9 73.7 1.0

A.G.Wrobel, D.J.Benton, C.Roustan, A.Borg, S.Hussain, S.R.Martin, P.B.Rosenthal, J.J.Skehel, S.J.Gamblin. Evolution of the Sars-Cov-2 Spike Protein in the Human Host. Nat Commun V. 13 1178 2022.
ISSN: ESSN 2041-1723
PubMed: 35246509
DOI: 10.1038/S41467-022-28768-W