Zinc in PDB 7q0k: Rna Polymerase Elongation Complex in Less-Swiveled Conformation

All present enzymatic activity of Rna Polymerase Elongation Complex in Less-Swiveled Conformation:
2.7.7.6;

The structure of Rna Polymerase Elongation Complex in Less-Swiveled Conformation also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Rna Polymerase Elongation Complex in Less-Swiveled Conformation (pdb code 7q0k). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Rna Polymerase Elongation Complex in Less-Swiveled Conformation, PDB code: 7q0k:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Rna Polymerase Elongation Complex in Less-Swiveled Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rna Polymerase Elongation Complex in Less-Swiveled Conformation within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:188.2 occ:1.00 N D:CYS72 2.1 157.2 1.0 SG D:CYS70 2.4 152.7 1.0 SG D:CYS72 2.4 157.2 1.0 CB D:CYS70 2.6 152.7 1.0 C D:CYS70 2.7 152.7 1.0 N D:GLY73 2.8 156.6 1.0 N D:LEU71 2.8 148.7 1.0 CA D:CYS72 2.8 157.2 1.0 CB D:CYS72 2.9 157.2 1.0 C D:LEU71 3.0 148.7 1.0 O D:CYS70 3.2 152.7 1.0 CA D:CYS70 3.2 152.7 1.0 C D:CYS72 3.2 157.2 1.0 CA D:LEU71 3.4 148.7 1.0 SG D:CYS88 3.6 137.8 1.0 CA D:GLY73 4.0 156.6 1.0 O D:LEU71 4.0 148.7 1.0 N D:LYS74 4.2 154.9 1.0 CB D:LEU71 4.3 148.7 1.0 N D:CYS70 4.3 152.7 1.0 SG D:CYS85 4.3 134.8 1.0 O D:CYS72 4.5 157.2 1.0 C D:GLY73 4.6 156.6 1.0 CB D:CYS85 4.9 134.8 1.0

Zinc binding site 2 out of 2 in the Rna Polymerase Elongation Complex in Less-Swiveled Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rna Polymerase Elongation Complex in Less-Swiveled Conformation within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1503 b:135.5 occ:1.00 SG D:CYS898 2.3 98.0 1.0 SG D:CYS888 2.3 99.9 1.0 SG D:CYS814 2.3 109.6 1.0 SG D:CYS895 2.3 103.4 1.0 CB D:CYS814 2.7 109.6 1.0 CB D:CYS888 3.2 99.9 1.0 CB D:CYS898 3.3 98.0 1.0 CB D:CYS895 3.4 103.4 1.0 CA D:CYS888 3.7 99.9 1.0 CA D:CYS814 4.0 109.6 1.0 N D:CYS895 4.1 103.4 1.0 N D:CYS814 4.1 109.6 1.0 N D:ASP889 4.2 103.8 1.0 CA D:CYS895 4.3 103.4 1.0 CA D:CYS898 4.4 98.0 1.0 N D:CYS898 4.4 98.0 1.0 C D:CYS888 4.5 99.9 1.0 CG2 D:THR890 4.7 106.5 1.0 OD2 D:ASP889 4.7 103.8 1.0 N D:CYS888 4.8 99.9 1.0 C D:CYS895 4.9 103.4 1.0 O D:CYS895 5.0 103.4 1.0 CD D:ARG883 5.0 117.2 1.0 C D:CYS814 5.0 109.6 1.0

C.Zhu, X.Guo, P.Dumas, M.Takacs, M.Abdelkareem, A.Vanden Broeck, C.Saint-Andre, G.Papai, C.Crucifix, J.Ortiz, A.Weixlbaumer. Transcription Factors Modulate Rna Polymerase Conformational Equilibrium. Nat Commun V. 13 1546 2022.
ISSN: ESSN 2041-1723
PubMed: 35318334
DOI: 10.1038/S41467-022-29148-0