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Atomistry » Zinc » PDB 7py5-7q8e » 7q0d | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 7py5-7q8e » 7q0d » |
Zinc in PDB 7q0d: Human Carbonic Anhydrase I in Complex with Methyl 2-(Benzenesulfonyl)- 4-Chloro-5-SulfamoylbenzoateEnzymatic activity of Human Carbonic Anhydrase I in Complex with Methyl 2-(Benzenesulfonyl)- 4-Chloro-5-Sulfamoylbenzoate
All present enzymatic activity of Human Carbonic Anhydrase I in Complex with Methyl 2-(Benzenesulfonyl)- 4-Chloro-5-Sulfamoylbenzoate:
4.2.1.1; Protein crystallography data
The structure of Human Carbonic Anhydrase I in Complex with Methyl 2-(Benzenesulfonyl)- 4-Chloro-5-Sulfamoylbenzoate, PDB code: 7q0d
was solved by
V.Paketuryte-Latve,
A.Smirnov,
E.Manakova,
S.Grazulis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7q0d:
The structure of Human Carbonic Anhydrase I in Complex with Methyl 2-(Benzenesulfonyl)- 4-Chloro-5-Sulfamoylbenzoate also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Carbonic Anhydrase I in Complex with Methyl 2-(Benzenesulfonyl)- 4-Chloro-5-Sulfamoylbenzoate
(pdb code 7q0d). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Human Carbonic Anhydrase I in Complex with Methyl 2-(Benzenesulfonyl)- 4-Chloro-5-Sulfamoylbenzoate, PDB code: 7q0d: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 7q0dGo back to Zinc Binding Sites List in 7q0d
Zinc binding site 1 out
of 2 in the Human Carbonic Anhydrase I in Complex with Methyl 2-(Benzenesulfonyl)- 4-Chloro-5-Sulfamoylbenzoate
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 7q0dGo back to Zinc Binding Sites List in 7q0d
Zinc binding site 2 out
of 2 in the Human Carbonic Anhydrase I in Complex with Methyl 2-(Benzenesulfonyl)- 4-Chloro-5-Sulfamoylbenzoate
Mono view Stereo pair view
Reference:
A.Zaksauskas,
E.Capkauskaite,
V.Paketuryte-Latve,
A.Smirnov,
J.Leitans,
A.Kazaks,
E.Dvinskis,
L.Stancaitis,
A.Mickeviciute,
J.Jachno,
L.Jezepcikas,
V.Linkuviene,
A.Sakalauskas,
E.Manakova,
S.Grazulis,
J.Matuliene,
K.Tars,
D.Matulis.
Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates As High Affinity and Selective Inhibitors of Carbonic Anhydrase IX. Int J Mol Sci V. 23 2021.
Page generated: Sat Apr 8 01:47:25 2023
ISSN: ESSN 1422-0067 PubMed: 35008553 DOI: 10.3390/IJMS23010130 |
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