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Zinc in PDB 7pjg: Lpxc Inhibitors with Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic with Activity Against Multidrug- Resistant Gram-Negative BacteriaEnzymatic activity of Lpxc Inhibitors with Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic with Activity Against Multidrug- Resistant Gram-Negative Bacteria
All present enzymatic activity of Lpxc Inhibitors with Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic with Activity Against Multidrug- Resistant Gram-Negative Bacteria:
3.5.1.108; Protein crystallography data
The structure of Lpxc Inhibitors with Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic with Activity Against Multidrug- Resistant Gram-Negative Bacteria, PDB code: 7pjg
was solved by
M.D.Ryan,
T.D.Pallin,
M.B.A.C.Lamers,
P.M.Leonard,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Lpxc Inhibitors with Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic with Activity Against Multidrug- Resistant Gram-Negative Bacteria
(pdb code 7pjg). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Lpxc Inhibitors with Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic with Activity Against Multidrug- Resistant Gram-Negative Bacteria, PDB code: 7pjg: Zinc binding site 1 out of 1 in 7pjgGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Lpxc Inhibitors with Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic with Activity Against Multidrug- Resistant Gram-Negative Bacteria
![]() Mono view ![]() Stereo pair view
Reference:
M.D.Ryan,
T.D.Pallin,
T.Mullins,
T.Blench,
I.Fraser,
J.Dallow,
N.Ahmed,
C.Ellwood,
S.Gaines,
J.Flores,
Y.Blackwell,
C.T.Garcia,
G.Spence,
A.Reeve,
T.Panchal,
B.Dominguez-Fernandez,
P.M.Leonard,
M.B.A.C.Lamers,
A.Arduin,
C.Fotinou,
E.Gancia,
D.E.Clark,
E.Bush,
J.Betts,
C.Richards,
T.Rea-Davies,
A.D.Keefe,
Y.Zhang,
H.T.Soutter,
P.A.Centrella,
M.A.Clark,
J.W.Cuozzo,
C.E.Dumelin,
S.Habeshian,
A.Hunt,
E.A.Sigel,
D.M.Troast,
B.L.M.Dejonge.
Lpxc Inhibitors with Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic with Activity Against Multidrug-Resistant Gram-Negative Bacteria To Be Published.
Page generated: Sat Apr 8 01:26:44 2023
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