Zinc in PDB 7phh: Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition)

The structure of Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition) also contains other interesting chemical elements:

Potassium

(K)

4 atoms

The binding sites of Zinc atom in the Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition) (pdb code 7phh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition), PDB code: 7phh:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn603 b:30.0 occ:1.00 SG B:CYS83 2.3 103.8 1.0 SG A:CYS105 2.4 105.6 1.0 SG A:CYS104 2.6 107.9 1.0 CB A:CYS105 2.8 105.6 1.0 CB B:CYS83 2.8 103.8 1.0 ND1 A:HIS77 2.9 99.3 1.0 CE1 A:HIS77 3.7 99.3 1.0 ND1 B:HIS112 3.7 102.1 1.0 N A:CYS105 3.8 105.6 1.0 CA A:CYS105 3.8 105.6 1.0 CG A:HIS77 3.9 99.3 1.0 CE1 B:HIS112 4.0 102.1 1.0 CB A:HIS77 4.1 99.3 1.0 C A:CYS104 4.2 107.9 1.0 CB A:CYS104 4.2 107.9 1.0 CA B:CYS83 4.4 103.8 1.0 O A:CYS104 4.6 107.9 1.0 CA A:HIS77 4.7 99.3 1.0 CA A:CYS104 4.8 107.9 1.0 CB A:GLU102 4.8 104.0 1.0 NE2 A:HIS77 4.8 99.3 1.0 N A:CYS78 4.9 102.5 1.0 CD2 A:HIS77 4.9 99.3 1.0

Zinc binding site 2 out of 4 in the Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn603 b:30.0 occ:1.00 SG D:CYS83 2.3 103.8 1.0 SG C:CYS105 2.4 105.6 1.0 SG C:CYS104 2.7 107.9 1.0 CB C:CYS105 2.7 105.6 1.0 CB D:CYS83 2.8 103.8 1.0 ND1 C:HIS77 2.9 99.3 1.0 CE1 C:HIS77 3.7 99.3 1.0 ND1 D:HIS112 3.7 102.1 1.0 N C:CYS105 3.8 105.6 1.0 CA C:CYS105 3.8 105.6 1.0 CG C:HIS77 3.8 99.3 1.0 CE1 D:HIS112 4.0 102.1 1.0 CB C:HIS77 4.1 99.3 1.0 C C:CYS104 4.2 107.9 1.0 CB C:CYS104 4.2 107.9 1.0 CA D:CYS83 4.4 103.8 1.0 O C:CYS104 4.6 107.9 1.0 CA C:HIS77 4.7 99.3 1.0 CA C:CYS104 4.8 107.9 1.0 CB C:GLU102 4.8 104.0 1.0 N C:CYS78 4.8 102.5 1.0 NE2 C:HIS77 4.9 99.3 1.0 CD2 C:HIS77 4.9 99.3 1.0

Zinc binding site 3 out of 4 in the Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn601 b:30.0 occ:1.00 SG C:CYS83 2.3 103.8 1.0 SG B:CYS105 2.5 105.6 1.0 SG B:CYS104 2.5 107.9 1.0 CB C:CYS83 2.8 103.8 1.0 CB B:CYS105 2.9 105.6 1.0 ND1 B:HIS77 2.9 99.3 1.0 CE1 B:HIS77 3.7 99.3 1.0 ND1 C:HIS112 3.7 102.1 1.0 N B:CYS105 3.8 105.6 1.0 CA B:CYS105 3.9 105.6 1.0 CG B:HIS77 3.9 99.3 1.0 CE1 C:HIS112 4.0 102.1 1.0 CB B:CYS104 4.1 107.9 1.0 CB B:HIS77 4.1 99.3 1.0 C B:CYS104 4.2 107.9 1.0 CA C:CYS83 4.4 103.8 1.0 O B:CYS104 4.6 107.9 1.0 CA B:CYS104 4.7 107.9 1.0 CB B:GLU102 4.8 104.0 1.0 CA B:HIS77 4.8 99.3 1.0 NE2 B:HIS77 4.8 99.3 1.0 CD2 B:HIS77 4.9 99.3 1.0

Zinc binding site 4 out of 4 in the Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Human Voltage-Gated Potassium Channel KV3.1 (Apo Condition) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn601 b:30.0 occ:1.00 SG A:CYS83 2.3 103.8 1.0 SG D:CYS105 2.4 105.6 1.0 SG D:CYS104 2.7 107.9 1.0 CB D:CYS105 2.8 105.6 1.0 ND1 D:HIS77 2.8 99.3 1.0 CB A:CYS83 2.8 103.8 1.0 CE1 D:HIS77 3.7 99.3 1.0 ND1 A:HIS112 3.7 102.1 1.0 N D:CYS105 3.8 105.6 1.0 CA D:CYS105 3.8 105.6 1.0 CG D:HIS77 3.8 99.3 1.0 CE1 A:HIS112 4.0 102.1 1.0 CB D:HIS77 4.0 99.3 1.0 C D:CYS104 4.2 107.9 1.0 CB D:CYS104 4.2 107.9 1.0 CA A:CYS83 4.4 103.8 1.0 O D:CYS104 4.6 107.9 1.0 CA D:HIS77 4.7 99.3 1.0 CB D:GLU102 4.8 104.0 1.0 CA D:CYS104 4.8 107.9 1.0 NE2 D:HIS77 4.8 99.3 1.0 N D:CYS78 4.9 102.5 1.0 CD2 D:HIS77 4.9 99.3 1.0

G.Chi, Q.Liang, A.Sridhar, J.B.Cowgill, K.Sader, M.Radjainia, P.Qian, P.Castro-Hartmann, S.Venkaya, N.K.Singh, G.Mckinley, A.Fernandez-Cid, S.M.M.Mukhopadhyay, N.A.Burgess-Brown, L.Delemotte, M.Covarrubias, K.L.Durr. Cryo-Em Structure of the Human KV3.1 Channel Reveals Gating Control By the Cytoplasmic T1 Domain. Nat Commun V. 13 4087 2022.
ISSN: ESSN 2041-1723
PubMed: 35840580
DOI: 10.1038/S41467-022-29594-W