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Zinc in PDB 7p2u: Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A 3- Chlorophenyl-Spiroindoline Capped Hydroxamate-Based Inhibitor, Bound to A Novel SiteProtein crystallography data
The structure of Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A 3- Chlorophenyl-Spiroindoline Capped Hydroxamate-Based Inhibitor, Bound to A Novel Site, PDB code: 7p2u
was solved by
F.Saccoccia,
S.Gemma,
G.Campiani,
G.Ruberti,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7p2u:
The structure of Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A 3- Chlorophenyl-Spiroindoline Capped Hydroxamate-Based Inhibitor, Bound to A Novel Site also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A 3- Chlorophenyl-Spiroindoline Capped Hydroxamate-Based Inhibitor, Bound to A Novel Site
(pdb code 7p2u). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A 3- Chlorophenyl-Spiroindoline Capped Hydroxamate-Based Inhibitor, Bound to A Novel Site, PDB code: 7p2u: Zinc binding site 1 out of 1 in 7p2uGo back to Zinc Binding Sites List in 7p2u
Zinc binding site 1 out
of 1 in the Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A 3- Chlorophenyl-Spiroindoline Capped Hydroxamate-Based Inhibitor, Bound to A Novel Site
Mono view Stereo pair view
Reference:
F.Saccoccia,
L.Pozzetti,
R.Gimmelli,
S.Butini,
A.Guidi,
G.Papoff,
M.Giannaccari,
S.Brogi,
V.Scognamiglio,
S.Gemma,
G.Ruberti,
G.Campiani.
Crystal Structures of Schistosoma Mansoni Histone Deacetylase 8 Reveal A Novel Binding Site For Allosteric Inhibitors. J.Biol.Chem. V. 298 02375 2022.
Page generated: Sat Apr 8 01:13:20 2023
ISSN: ESSN 1083-351X PubMed: 35970392 DOI: 10.1016/J.JBC.2022.102375 |
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