Zinc in PDB 7oyg: Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase

Enzymatic activity of Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase

All present enzymatic activity of Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase:
2.7.7.48; 3.4.19.12; 3.4.22.69; 3.6.4.12; 3.6.4.13;

Zinc Binding Sites:

The binding sites of Zinc atom in the Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase (pdb code 7oyg). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase, PDB code: 7oyg:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 7oyg

Go back to Zinc Binding Sites List in 7oyg
Zinc binding site 1 out of 4 in the Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2000

b:43.9
occ:1.00
 ND1 A:HIS295 2.1 24.7 1.0
SG A:CYS301 2.3 25.1 1.0
SG A:CYS310 2.3 24.3 1.0
SG A:CYS306 2.3 26.0 1.0
CE1 A:HIS295 2.9 24.7 1.0
CG A:HIS295 3.2 24.7 1.0
CB A:CYS301 3.2 25.1 1.0
O A:CYS306 3.3 26.0 1.0
CA A:CYS301 3.3 25.1 1.0
CB A:CYS306 3.4 26.0 1.0
CB A:HIS295 3.6 24.7 1.0
C A:CYS306 3.7 26.0 1.0
CB A:CYS310 3.9 24.3 1.0
CA A:CYS306 4.0 26.0 1.0
NE2 A:HIS295 4.1 24.7 1.0
CD2 A:HIS295 4.2 24.7 1.0
O A:ASN300 4.2 25.3 1.0
N A:CYS301 4.3 25.1 1.0
N A:LEU302 4.3 25.5 1.0
C A:CYS301 4.4 25.1 1.0
N A:HIS295 4.4 24.7 1.0
N A:ILE307 4.4 24.1 1.0
CA A:HIS295 4.6 24.7 1.0
C A:ASN300 4.6 25.3 1.0
CA A:ILE307 4.9 24.1 1.0
N A:CYS310 5.0 24.3 1.0

Zinc binding site 2 out of 4 in 7oyg

Go back to Zinc Binding Sites List in 7oyg
Zinc binding site 2 out of 4 in the Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2001

b:41.0
occ:1.00
 SG A:CYS487 2.3 28.9 1.0
SG A:CYS645 2.3 31.0 1.0
SG A:CYS646 2.3 27.6 1.0
ND1 A:HIS642 2.3 26.2 1.0
CG A:HIS642 3.2 26.2 1.0
CE1 A:HIS642 3.3 26.2 1.0
CB A:CYS487 3.4 28.9 1.0
CB A:CYS645 3.5 31.0 1.0
CB A:CYS646 3.5 27.6 1.0
CB A:HIS642 3.5 26.2 1.0
C A:CYS645 3.7 31.0 1.0
N A:CYS646 3.8 27.6 1.0
N A:CYS487 3.9 28.9 1.0
O A:CYS645 3.9 31.0 1.0
CA A:CYS646 4.2 27.6 1.0
CA A:CYS645 4.2 31.0 1.0
CA A:CYS487 4.2 28.9 1.0
CE1 A:PHE571 4.3 26.0 1.0
CA A:HIS642 4.3 26.2 1.0
CD2 A:HIS642 4.4 26.2 1.0
NE2 A:HIS642 4.4 26.2 1.0
O A:HIS642 4.6 26.2 1.0
C A:GLY486 4.6 26.2 1.0
CD1 A:PHE571 4.8 26.0 1.0
N A:CYS645 4.8 31.0 1.0
C A:HIS642 4.9 26.2 1.0
CE A:LYS532 4.9 28.8 1.0
CA A:GLY486 4.9 26.2 1.0

Zinc binding site 3 out of 4 in 7oyg

Go back to Zinc Binding Sites List in 7oyg
Zinc binding site 3 out of 4 in the Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2000

b:43.9
occ:1.00
 ND1 D:HIS295 2.1 24.7 1.0
SG D:CYS301 2.3 25.1 1.0
SG D:CYS310 2.3 24.3 1.0
SG D:CYS306 2.3 26.0 1.0
CE1 D:HIS295 2.9 24.7 1.0
CG D:HIS295 3.2 24.7 1.0
CB D:CYS301 3.2 25.1 1.0
O D:CYS306 3.3 26.0 1.0
CA D:CYS301 3.3 25.1 1.0
CB D:CYS306 3.4 26.0 1.0
CB D:HIS295 3.6 24.7 1.0
C D:CYS306 3.7 26.0 1.0
CB D:CYS310 3.9 24.3 1.0
CA D:CYS306 4.0 26.0 1.0
NE2 D:HIS295 4.1 24.7 1.0
CD2 D:HIS295 4.2 24.7 1.0
O D:ASN300 4.2 25.3 1.0
N D:CYS301 4.3 25.1 1.0
N D:LEU302 4.3 25.5 1.0
C D:CYS301 4.4 25.1 1.0
N D:HIS295 4.4 24.7 1.0
N D:ILE307 4.4 24.1 1.0
CA D:HIS295 4.6 24.7 1.0
C D:ASN300 4.6 25.3 1.0
CA D:ILE307 4.9 24.1 1.0
N D:CYS310 5.0 24.3 1.0

Zinc binding site 4 out of 4 in 7oyg

Go back to Zinc Binding Sites List in 7oyg
Zinc binding site 4 out of 4 in the Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Dimeric Form of Sars-Cov-2 Rna-Dependent Rna Polymerase within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2001

b:41.0
occ:1.00
 SG D:CYS487 2.3 28.9 1.0
SG D:CYS645 2.3 31.0 1.0
SG D:CYS646 2.3 27.6 1.0
ND1 D:HIS642 2.3 26.2 1.0
CG D:HIS642 3.2 26.2 1.0
CE1 D:HIS642 3.3 26.2 1.0
CB D:CYS487 3.4 28.9 1.0
CB D:CYS646 3.5 27.6 1.0
CB D:CYS645 3.5 31.0 1.0
CB D:HIS642 3.5 26.2 1.0
C D:CYS645 3.7 31.0 1.0
N D:CYS646 3.8 27.6 1.0
N D:CYS487 3.9 28.9 1.0
O D:CYS645 3.9 31.0 1.0
CA D:CYS646 4.2 27.6 1.0
CA D:CYS645 4.2 31.0 1.0
CA D:CYS487 4.2 28.9 1.0
CE1 D:PHE571 4.3 26.0 1.0
CA D:HIS642 4.3 26.2 1.0
CD2 D:HIS642 4.4 26.2 1.0
NE2 D:HIS642 4.4 26.2 1.0
O D:HIS642 4.6 26.2 1.0
C D:GLY486 4.6 26.2 1.0
CD1 D:PHE571 4.8 26.0 1.0
N D:CYS645 4.8 31.0 1.0
C D:HIS642 4.9 26.2 1.0
CE D:LYS532 4.9 28.8 1.0
CA D:GLY486 4.9 26.2 1.0

Reference:

F.A.Jochheim, D.Tegunov, H.S.Hillen, J.Schmitzova, G.Kokic, C.Dienemann, P.Cramer. Dimeric Form of Sars-Cov-2 Polymerase To Be Published.
Page generated: Wed Oct 30 08:54:09 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy