Zinc in PDB 7nz8: Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex 2

All present enzymatic activity of Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex 2:
3.5.4.33;

The structure of Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex 2, PDB code: 7nz8 was solved by E.Ramos Morales, C.Romier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.44 / 2.12
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	52.291, 106.832, 130.58, 90, 90, 90
R / Rfree (%)	20.1 / 23.3

The binding sites of Zinc atom in the Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex 2 (pdb code 7nz8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex 2, PDB code: 7nz8:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn200 b:36.8 occ:1.00 O A:HOH313 2.2 32.2 1.0 ND1 A:HIS71 2.2 34.1 1.0 SG A:CYS110 2.3 36.2 1.0 SG A:CYS107 2.3 34.3 1.0 CG A:HIS71 3.1 35.1 1.0 CE1 A:HIS71 3.2 36.7 1.0 CB A:CYS110 3.3 32.4 1.0 CB A:HIS71 3.4 35.4 1.0 CB A:CYS107 3.4 34.0 1.0 N A:CYS107 3.9 32.2 1.0 OE2 A:GLU73 3.9 34.1 1.0 N A:CYS110 3.9 31.7 1.0 CE A:MET109 4.1 32.4 1.0 OE1 A:GLU73 4.1 33.7 1.0 CA A:CYS107 4.2 32.9 1.0 CA A:CYS110 4.2 29.2 1.0 NE2 A:HIS71 4.3 39.6 1.0 CD2 A:HIS71 4.3 38.5 1.0 CD A:GLU73 4.3 34.4 1.0 O A:HOH358 4.5 33.8 1.0 O A:HOH348 4.5 38.0 1.0 O A:HOH341 4.5 37.7 1.0 C A:CYS107 4.7 33.5 1.0 O A:CYS107 4.8 32.0 1.0 NE2 B:HIS298 4.9 36.0 1.0 O A:HOH359 4.9 25.2 1.0 CB A:MET109 4.9 30.6 1.0 CA A:HIS71 4.9 35.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Mouse ADAT2/ADAT3 Trna Deamination Complex 2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn400 b:33.9 occ:1.00 OD2 B:ASP348 2.0 35.3 1.0 ND1 B:HIS223 2.2 33.3 1.0 SG B:CYS289 2.3 36.1 1.0 SG B:CYS292 2.3 34.6 1.0 CG B:ASP348 2.9 36.0 1.0 OD1 B:ASP348 3.1 40.2 1.0 CE1 B:HIS223 3.2 33.6 1.0 CG B:HIS223 3.2 35.5 1.0 CB B:CYS289 3.4 35.2 1.0 CB B:CYS292 3.4 34.2 1.0 CB B:HIS223 3.5 34.0 1.0 N B:CYS289 3.8 34.2 1.0 N B:CYS292 4.0 31.3 1.0 O B:HOH559 4.0 36.1 1.0 CA B:CYS289 4.1 32.4 1.0 NE2 B:HIS223 4.3 34.6 1.0 CB B:ASP348 4.3 35.8 1.0 CA B:CYS292 4.3 34.3 1.0 CD2 B:HIS223 4.3 32.4 1.0 CE B:MET291 4.5 31.2 1.0 C B:CYS289 4.7 34.3 1.0 O B:CYS289 4.8 32.8 1.0 N B:PRO349 4.9 41.1 1.0 CA B:PRO349 4.9 38.0 1.0 C B:PRO288 4.9 33.6 1.0 C B:ASP348 5.0 39.6 1.0 CB B:MET291 5.0 26.4 1.0

E.Ramos Morales, C.Romier. The Structure of the Mouse ADAT2/ADAT3 Complex Reveals the Molecular Basis For Mammalian Trna Wobble Adenosine to Inosine Deamination To Be Published.