Zinc in PDB 7nsk: Endoplasmic Reticulum Aminopeptidase 2 Complexed with A Hydroxamic Ligand

The structure of Endoplasmic Reticulum Aminopeptidase 2 Complexed with A Hydroxamic Ligand, PDB code: 7nsk was solved by A.Mpakali, P.Giastas, E.Stratikos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	75.56 / 3.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	75.559, 134.572, 128.638, 90, 90.2, 90
R / Rfree (%)	18.7 / 25.4

The binding sites of Zinc atom in the Endoplasmic Reticulum Aminopeptidase 2 Complexed with A Hydroxamic Ligand (pdb code 7nsk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Endoplasmic Reticulum Aminopeptidase 2 Complexed with A Hydroxamic Ligand, PDB code: 7nsk:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Endoplasmic Reticulum Aminopeptidase 2 Complexed with A Hydroxamic Ligand


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Endoplasmic Reticulum Aminopeptidase 2 Complexed with A Hydroxamic Ligand within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:30.8 occ:1.00 NE2 A:HIS374 1.9 26.6 1.0 O32 A:UQE1007 1.9 62.5 0.2 OE2 A:GLU393 2.0 34.0 1.0 O11 A:UQE1007 2.0 67.0 0.8 NE2 A:HIS370 2.1 34.9 1.0 O34 A:UQE1007 2.2 58.5 0.2 O09 A:UQE1007 2.3 61.9 0.8 S33 A:UQE1007 2.7 109.7 0.2 CE1 A:HIS374 2.8 31.1 1.0 C12 A:UQE1007 2.8 113.5 0.8 CD A:GLU393 2.9 30.5 1.0 CD2 A:HIS374 2.9 28.7 1.0 N10 A:UQE1007 3.0 64.7 0.8 CE1 A:HIS370 3.0 32.5 1.0 CD2 A:HIS370 3.0 33.9 1.0 OE1 A:GLU393 3.0 32.1 1.0 S21 A:UQE1007 3.8 72.4 0.2 C31 A:UQE1007 3.8 70.2 0.2 N20 A:UQE1007 3.8 64.4 0.2 OE1 A:GLU371 4.0 39.8 1.0 ND1 A:HIS374 4.0 26.9 1.0 CE2 A:TYR455 4.0 34.9 1.0 OE1 A:GLU337 4.0 41.1 1.0 CG A:HIS374 4.1 25.6 1.0 OH A:TYR455 4.1 41.4 1.0 ND1 A:HIS370 4.1 30.1 1.0 CG A:HIS370 4.2 27.9 1.0 CG A:GLU393 4.3 31.4 1.0 C13 A:UQE1007 4.3 68.7 0.8 CB A:ALA396 4.6 30.6 1.0 CZ A:TYR455 4.6 34.1 1.0 OE2 A:GLU371 4.7 38.2 1.0 CD A:GLU371 4.7 35.8 1.0 C06 A:UQE1007 4.7 66.9 0.8 C07 A:UQE1007 4.7 69.5 0.8 O A:HOH1106 4.8 35.3 1.0 CA A:GLU393 4.8 22.8 1.0 CB A:GLU393 4.9 29.6 1.0 C19 A:UQE1007 4.9 61.6 0.2 CD A:GLU337 4.9 38.1 1.0 C08 A:UQE1007 5.0 67.4 0.8

Zinc binding site 2 out of 2 in the Endoplasmic Reticulum Aminopeptidase 2 Complexed with A Hydroxamic Ligand


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Endoplasmic Reticulum Aminopeptidase 2 Complexed with A Hydroxamic Ligand within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:51.9 occ:1.00 NE2 B:HIS374 2.0 49.6 1.0 OE1 B:GLU393 2.0 56.0 1.0 NE2 B:HIS370 2.1 58.4 1.0 O09 B:UQE1004 2.2 65.9 1.0 O11 B:UQE1004 2.5 64.8 1.0 CE1 B:HIS374 2.8 52.3 1.0 CD B:GLU393 2.8 54.8 1.0 CD2 B:HIS374 2.9 51.0 1.0 N10 B:UQE1004 2.9 64.5 1.0 CE1 B:HIS370 2.9 60.4 1.0 OE2 B:GLU393 3.0 51.0 1.0 C12 B:UQE1004 3.0 62.7 1.0 CD2 B:HIS370 3.2 62.3 1.0 ND1 B:HIS374 3.8 53.8 1.0 CG B:HIS374 3.9 51.9 1.0 ND1 B:HIS370 4.1 64.0 1.0 CE2 B:TYR455 4.2 61.6 1.0 CG B:HIS370 4.2 61.6 1.0 CG B:GLU393 4.3 56.0 1.0 OH B:TYR455 4.3 61.8 1.0 CB B:ALA396 4.4 48.6 1.0 OE1 B:GLU371 4.5 56.5 1.0 CA B:GLU393 4.5 53.8 1.0 C13 B:UQE1004 4.5 74.7 1.0 CZ B:TYR455 4.6 60.3 1.0 CB B:GLU393 4.7 56.9 1.0 C07 B:UQE1004 4.7 79.2 1.0 C02 B:UQE1004 4.8 70.9 1.0 OE2 B:GLU371 4.8 60.2 1.0 OE1 B:GLU337 4.9 55.0 1.0 C08 B:UQE1004 4.9 76.6 1.0 CD B:GLU371 5.0 59.2 1.0

A.Mpakali, P.Giastas, E.Stratikos. Endoplasmic Reticulum Aminopeptidase 2 in Complex with A Phosphinic Ligand To Be Published.