Zinc in PDB 7lw2: Crystal Structure of Ev-D68 2A Protease N84T Mutant

Enzymatic activity of Crystal Structure of Ev-D68 2A Protease N84T Mutant

All present enzymatic activity of Crystal Structure of Ev-D68 2A Protease N84T Mutant:
3.4.22.29;

Protein crystallography data

The structure of Crystal Structure of Ev-D68 2A Protease N84T Mutant, PDB code: 7lw2 was solved by C.Liu, M.-Y.Lee, W.Liu, J.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.43 / 2.57
Space group P 4
Cell size a, b, c (Å), α, β, γ (°) 119.255, 119.255, 80.326, 90, 90, 90
R / Rfree (%) 21.6 / 24.2

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Ev-D68 2A Protease N84T Mutant (pdb code 7lw2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Crystal Structure of Ev-D68 2A Protease N84T Mutant, PDB code: 7lw2:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in 7lw2

Go back to Zinc Binding Sites List in 7lw2
Zinc binding site 1 out of 6 in the Crystal Structure of Ev-D68 2A Protease N84T Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Ev-D68 2A Protease N84T Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn201

b:77.8
occ:1.00
ND1 E:HIS115 2.1 62.1 1.0
SG E:CYS53 2.3 65.0 1.0
SG E:CYS113 2.3 59.7 1.0
SG E:CYS55 2.3 72.8 1.0
HB2 E:CYS55 2.8 67.1 1.0
HB2 E:HIS115 2.9 60.4 1.0
CE1 E:HIS115 3.0 55.2 1.0
HB2 E:CYS53 3.0 63.4 1.0
CB E:CYS53 3.0 52.9 1.0
HB3 E:CYS53 3.1 63.4 1.0
CG E:HIS115 3.1 55.3 1.0
HE1 E:HIS115 3.1 66.1 1.0
CB E:CYS55 3.2 56.0 1.0
H E:HIS115 3.4 50.9 1.0
CB E:CYS113 3.5 41.4 1.0
CB E:HIS115 3.5 50.4 1.0
H E:CYS55 3.5 62.0 1.0
HB1 E:ALA51 3.7 60.0 1.0
HB3 E:CYS55 3.8 67.1 1.0
HD2 E:PRO114 3.9 65.7 1.0
NE2 E:HIS115 4.1 57.1 1.0
N E:HIS115 4.1 42.5 1.0
OG B:SER68 4.1 57.0 1.0
CD2 E:HIS115 4.2 56.2 1.0
HB3 E:HIS115 4.2 60.4 1.0
N E:CYS55 4.2 51.8 1.0
CA E:CYS55 4.3 57.6 1.0
HH11 E:ARG135 4.4 72.2 1.0
CA E:HIS115 4.4 42.0 1.0
CA E:CYS53 4.5 44.0 1.0
CB E:ALA51 4.5 50.1 1.0
HH12 E:ARG135 4.6 72.2 1.0
CD1 E:ILE118 4.6 64.5 1.0
HA E:CYS55 4.7 69.0 1.0
HB2 E:ALA51 4.7 60.0 1.0
CD E:PRO114 4.7 54.9 1.0
CA E:CYS113 4.7 51.6 1.0
H E:LYS54 4.8 61.8 1.0
HG12 E:ILE118 4.8 69.1 1.0
N E:PRO114 4.8 53.9 1.0
NH1 E:ARG135 4.8 60.2 1.0
HE2 E:HIS115 4.9 68.4 1.0
C E:CYS113 4.9 52.9 1.0
HB3 E:ALA51 4.9 60.0 1.0
HG13 E:ILE118 4.9 69.1 1.0
H E:GLY116 5.0 70.2 1.0
N E:LYS54 5.0 51.6 1.0

Zinc binding site 2 out of 6 in 7lw2

Go back to Zinc Binding Sites List in 7lw2
Zinc binding site 2 out of 6 in the Crystal Structure of Ev-D68 2A Protease N84T Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Ev-D68 2A Protease N84T Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn201

b:82.0
occ:1.00
ND1 A:HIS115 2.1 67.9 1.0
SG A:CYS53 2.3 75.9 1.0
SG A:CYS55 2.3 78.1 1.0
SG A:CYS113 2.3 54.4 1.0
HB2 A:CYS55 2.8 78.1 1.0
CE1 A:HIS115 2.9 63.2 1.0
HB2 A:HIS115 2.9 72.4 1.0
HB2 A:CYS53 3.0 81.8 1.0
HE1 A:HIS115 3.1 75.7 1.0
CB A:CYS53 3.1 68.2 1.0
CG A:HIS115 3.1 61.9 1.0
CB A:CYS55 3.1 65.2 1.0
HB3 A:CYS53 3.2 81.8 1.0
HB2 A:CYS113 3.4 58.9 1.0
H A:CYS55 3.4 77.8 1.0
CB A:CYS113 3.5 49.1 1.0
H A:HIS115 3.5 73.5 1.0
CB A:HIS115 3.5 60.4 1.0
HB1 A:ALA51 3.7 61.4 1.0
HB3 A:CYS55 3.8 78.1 1.0
HB3 A:CYS113 3.8 58.9 1.0
NE2 A:HIS115 4.1 74.3 1.0
N A:CYS55 4.1 65.0 1.0
CD2 A:HIS115 4.2 57.8 1.0
HD2 A:PRO114 4.2 70.3 1.0
HB3 A:HIS115 4.2 72.4 1.0
CA A:CYS55 4.2 63.2 1.0
N A:HIS115 4.3 61.3 1.0
CB A:ALA51 4.5 51.2 1.0
CA A:HIS115 4.5 60.7 1.0
CA A:CYS53 4.6 66.1 1.0
CD1 A:ILE118 4.6 65.5 1.0
HA A:CYS55 4.6 75.8 1.0
HB2 A:ALA51 4.7 61.4 1.0
H A:LYS54 4.7 86.5 1.0
HG12 A:ILE118 4.7 76.2 1.0
HB3 A:ALA51 4.8 61.4 1.0
CA A:CYS113 4.8 54.4 1.0
HE2 A:HIS115 4.8 89.0 1.0
N A:PRO114 4.9 52.6 1.0
N A:LYS54 4.9 72.2 1.0
C A:CYS113 5.0 57.1 1.0
CD A:PRO114 5.0 58.7 1.0
C A:CYS53 5.0 71.5 1.0

Zinc binding site 3 out of 6 in 7lw2

Go back to Zinc Binding Sites List in 7lw2
Zinc binding site 3 out of 6 in the Crystal Structure of Ev-D68 2A Protease N84T Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Ev-D68 2A Protease N84T Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn201

b:67.4
occ:1.00
ND1 B:HIS115 2.0 56.9 1.0
SG B:CYS53 2.3 72.2 1.0
SG B:CYS55 2.3 55.0 1.0
SG B:CYS113 2.3 64.8 1.0
HB2 B:CYS55 2.6 69.7 1.0
CE1 B:HIS115 2.9 61.7 1.0
HE1 B:HIS115 3.0 73.9 1.0
CB B:CYS55 3.0 58.2 1.0
HB2 B:HIS115 3.0 60.6 1.0
HB2 B:CYS53 3.1 79.5 1.0
CB B:CYS53 3.1 66.3 1.0
CG B:HIS115 3.2 52.7 1.0
HB3 B:CYS53 3.2 79.5 1.0
HD11 B:ILE118 3.4 68.7 1.0
HB2 B:CYS113 3.4 58.2 1.0
H B:CYS55 3.4 65.4 1.0
CB B:CYS113 3.5 48.6 1.0
HB1 B:ALA51 3.6 69.0 1.0
CB B:HIS115 3.6 50.6 1.0
H B:HIS115 3.6 64.8 1.0
HB3 B:CYS55 3.6 69.7 1.0
HG E:SER68 3.7 82.1 1.0
HB3 B:CYS113 3.8 58.2 1.0
NE2 B:HIS115 4.1 58.2 1.0
N B:CYS55 4.1 54.6 1.0
HD2 B:PRO114 4.1 57.9 1.0
CA B:CYS55 4.1 58.2 1.0
HH11 B:ARG135 4.2 72.9 1.0
CD2 B:HIS115 4.2 58.6 1.0
HB3 B:HIS115 4.3 60.6 1.0
CD1 B:ILE118 4.4 57.3 1.0
N B:HIS115 4.4 54.1 1.0
CB B:ALA51 4.5 57.6 1.0
HH12 B:ARG135 4.5 72.9 1.0
OG E:SER68 4.5 68.5 1.0
HA B:CYS55 4.5 69.7 1.0
CA B:CYS53 4.6 57.1 1.0
CA B:HIS115 4.6 49.2 1.0
HG12 B:ILE118 4.6 66.2 1.0
HB2 B:ALA51 4.7 69.0 1.0
NH1 B:ARG135 4.7 60.8 1.0
HD13 B:ILE118 4.7 68.7 1.0
H B:LYS54 4.7 69.1 1.0
HG13 B:ILE118 4.7 66.2 1.0
HB3 B:ALA51 4.8 69.0 1.0
HE2 B:HIS115 4.8 69.7 1.0
CA B:CYS113 4.8 45.0 1.0
CG1 B:ILE118 4.9 55.2 1.0
CD B:PRO114 4.9 48.3 1.0
HD12 B:ILE118 4.9 68.7 1.0
N B:LYS54 5.0 57.6 1.0

Zinc binding site 4 out of 6 in 7lw2

Go back to Zinc Binding Sites List in 7lw2
Zinc binding site 4 out of 6 in the Crystal Structure of Ev-D68 2A Protease N84T Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Ev-D68 2A Protease N84T Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn201

b:77.8
occ:1.00
ND1 C:HIS115 2.0 59.1 1.0
SG C:CYS53 2.3 81.0 1.0
SG C:CYS113 2.3 64.7 1.0
SG C:CYS55 2.3 67.0 1.0
HB2 C:CYS55 2.7 75.3 1.0
CE1 C:HIS115 2.9 59.8 1.0
HE1 C:HIS115 2.9 71.6 1.0
HB2 C:HIS115 3.1 76.8 1.0
CB C:CYS55 3.1 62.8 1.0
CG C:HIS115 3.2 67.8 1.0
HB2 C:CYS53 3.3 81.8 1.0
CB C:CYS53 3.3 68.2 1.0
HB2 C:CYS113 3.4 71.6 1.0
HB3 C:CYS53 3.4 81.8 1.0
CB C:CYS113 3.5 59.7 1.0
H C:CYS55 3.5 76.5 1.0
H C:HIS115 3.6 69.8 1.0
HB1 C:ALA51 3.6 85.7 1.0
CB C:HIS115 3.6 64.1 1.0
HB3 C:CYS55 3.7 75.3 1.0
HB3 C:CYS113 3.8 71.6 1.0
NE2 C:HIS115 4.0 65.2 1.0
HD2 C:PRO114 4.1 72.7 1.0
N C:CYS55 4.2 63.8 1.0
CD2 C:HIS115 4.2 64.9 1.0
CA C:CYS55 4.2 58.0 1.0
CD1 C:ILE118 4.3 69.7 1.0
HB3 C:HIS115 4.3 76.8 1.0
N C:HIS115 4.3 58.2 1.0
CB C:ALA51 4.4 71.5 1.0
HB2 C:ALA51 4.5 85.7 1.0
HA C:CYS55 4.6 69.5 1.0
CA C:HIS115 4.6 53.9 1.0
HG12 C:ILE118 4.7 84.6 1.0
CA C:CYS53 4.7 61.8 1.0
HB3 C:ALA51 4.7 85.7 1.0
HE2 C:HIS115 4.8 78.2 1.0
CA C:CYS113 4.8 53.8 1.0
HH21 C:ARG135 4.9 90.9 1.0
H C:LYS54 4.9 66.0 1.0
N C:PRO114 5.0 69.8 1.0
CD C:PRO114 5.0 60.6 1.0
C C:CYS113 5.0 62.3 1.0

Zinc binding site 5 out of 6 in 7lw2

Go back to Zinc Binding Sites List in 7lw2
Zinc binding site 5 out of 6 in the Crystal Structure of Ev-D68 2A Protease N84T Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Crystal Structure of Ev-D68 2A Protease N84T Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn201

b:84.8
occ:1.00
ND1 D:HIS115 2.0 45.9 1.0
SG D:CYS113 2.3 79.6 1.0
SG D:CYS53 2.3 81.0 1.0
SG D:CYS55 2.3 67.1 1.0
HB2 D:CYS55 2.7 82.8 1.0
CE1 D:HIS115 2.9 50.8 1.0
HB2 D:HIS115 3.0 82.4 1.0
HE1 D:HIS115 3.0 60.8 1.0
CB D:CYS55 3.1 69.1 1.0
CG D:HIS115 3.1 56.3 1.0
HB2 D:CYS53 3.2 78.1 1.0
CB D:CYS53 3.3 65.2 1.0
HB2 D:CYS113 3.4 82.2 1.0
HB3 D:CYS53 3.4 78.1 1.0
H D:CYS55 3.4 96.4 1.0
H D:HIS115 3.4 79.0 1.0
CB D:CYS113 3.5 68.6 1.0
CB D:HIS115 3.5 68.8 1.0
HD11 D:ILE118 3.7 74.4 1.0
HB3 D:CYS55 3.7 82.8 1.0
HB1 D:ALA51 3.8 90.2 1.0
HB3 D:CYS113 3.8 82.2 1.0
HD2 D:PRO114 3.9 73.2 1.0
NE2 D:HIS115 4.0 59.2 1.0
N D:CYS55 4.1 80.5 1.0
CA D:CYS55 4.2 72.4 1.0
CD2 D:HIS115 4.2 58.5 1.0
N D:HIS115 4.2 66.0 1.0
HB3 D:HIS115 4.2 82.4 1.0
CA D:HIS115 4.5 69.9 1.0
HA D:CYS55 4.6 86.7 1.0
CD1 D:ILE118 4.6 62.1 1.0
CB D:ALA51 4.6 75.3 1.0
CA D:CYS53 4.7 64.9 1.0
HD13 D:ILE118 4.7 74.4 1.0
HB2 D:ALA51 4.7 90.2 1.0
HG12 D:ILE118 4.8 74.4 1.0
CD D:PRO114 4.8 61.1 1.0
CA D:CYS113 4.8 59.5 1.0
HE2 D:HIS115 4.8 70.9 1.0
N D:PRO114 4.8 57.5 1.0
H D:LYS54 4.8 90.5 1.0
C D:CYS113 4.9 55.3 1.0
HE D:ARG135 4.9 88.8 1.0
HB3 D:ALA51 5.0 90.2 1.0

Zinc binding site 6 out of 6 in 7lw2

Go back to Zinc Binding Sites List in 7lw2
Zinc binding site 6 out of 6 in the Crystal Structure of Ev-D68 2A Protease N84T Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Crystal Structure of Ev-D68 2A Protease N84T Mutant within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn201

b:90.3
occ:1.00
ND1 F:HIS115 2.1 59.1 1.0
SG F:CYS53 2.3 73.8 1.0
SG F:CYS113 2.3 62.5 1.0
SG F:CYS55 2.3 85.0 1.0
HB2 F:CYS53 2.8 76.7 1.0
HB2 F:CYS55 2.9 86.5 1.0
CB F:CYS53 2.9 64.0 1.0
HB3 F:CYS53 2.9 76.7 1.0
CE1 F:HIS115 2.9 50.4 1.0
HB2 F:HIS115 3.0 64.5 1.0
HE1 F:HIS115 3.1 60.4 1.0
CG F:HIS115 3.2 50.9 1.0
CB F:CYS55 3.2 72.2 1.0
HB2 F:CYS113 3.5 77.8 1.0
H F:CYS55 3.5 90.3 1.0
CB F:CYS113 3.5 64.9 1.0
CB F:HIS115 3.6 53.9 1.0
H F:HIS115 3.6 79.3 1.0
HB1 F:ALA51 3.7 86.7 1.0
HB3 F:CYS55 3.8 86.5 1.0
HD11 F:ILE118 3.8 76.2 1.0
HB3 F:CYS113 3.8 77.8 1.0
NE2 F:HIS115 4.1 46.9 1.0
HD2 F:PRO114 4.1 77.8 1.0
N F:CYS55 4.2 75.3 1.0
CD2 F:HIS115 4.2 49.8 1.0
HB3 F:HIS115 4.2 64.5 1.0
CA F:CYS55 4.3 74.2 1.0
N F:HIS115 4.3 66.2 1.0
CA F:CYS53 4.4 65.0 1.0
CB F:ALA51 4.5 72.4 1.0
HE F:ARG135 4.6 85.6 1.0
CA F:HIS115 4.6 60.2 1.0
HH21 F:ARG135 4.6 97.5 1.0
H F:LYS54 4.6 86.2 1.0
HA F:CYS55 4.7 88.9 1.0
CD1 F:ILE118 4.7 63.6 1.0
HB2 F:ALA51 4.8 86.7 1.0
HB3 F:ALA51 4.8 86.7 1.0
HG13 F:ILE118 4.8 78.2 1.0
HG12 F:ILE118 4.9 78.2 1.0
HE2 F:HIS115 4.9 56.2 1.0
CA F:CYS113 4.9 56.4 1.0
N F:LYS54 4.9 72.0 1.0
HA F:CYS53 4.9 77.9 1.0
C F:CYS53 4.9 66.1 1.0
CD F:PRO114 5.0 64.9 1.0
N F:PRO114 5.0 59.3 1.0

Reference:

C.Liu, M.-Y.Lee, C.Ma, W.Liu, J.Wang. Crystal Structure of Ev-D68 2A Protease C107A Mutant To Be Published.
Page generated: Sat Apr 8 00:33:11 2023

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy