Zinc in PDB 7lhe: Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State (pdb code 7lhe). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State, PDB code: 7lhe:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 7lhe

Go back to Zinc Binding Sites List in 7lhe
Zinc binding site 1 out of 4 in the Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2805

b:127.2
occ:1.00
CB A:CYS2614 1.7 107.9 1.0
NE2 A:HIS2631 2.0 113.8 1.0
ND1 A:HIS2636 2.1 109.8 1.0
SG A:CYS2614 2.3 107.9 1.0
SG A:CYS2611 2.3 105.1 1.0
CG A:HIS2636 2.8 109.8 1.0
CE1 A:HIS2631 3.0 113.8 1.0
CB A:HIS2636 3.0 109.8 1.0
CD2 A:HIS2631 3.0 113.8 1.0
CA A:CYS2614 3.2 107.9 1.0
CE1 A:HIS2636 3.2 109.8 1.0
N A:CYS2614 3.6 107.9 1.0
CB A:CYS2611 3.6 105.1 1.0
CD2 A:HIS2636 4.1 109.8 1.0
ND1 A:HIS2631 4.1 113.8 1.0
CG A:HIS2631 4.1 113.8 1.0
NE2 A:HIS2636 4.2 109.8 1.0
C A:CYS2614 4.2 107.9 1.0
CA A:HIS2636 4.5 109.8 1.0
N A:GLY2615 4.7 106.4 1.0
O A:HIS2631 4.9 113.8 1.0
C A:ILE2613 4.9 99.1 1.0
CA A:CYS2611 5.0 105.1 1.0

Zinc binding site 2 out of 4 in 7lhe

Go back to Zinc Binding Sites List in 7lhe
Zinc binding site 2 out of 4 in the Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2805

b:126.9
occ:1.00
CB D:CYS2614 1.7 107.9 1.0
NE2 D:HIS2631 2.0 113.8 1.0
ND1 D:HIS2636 2.1 109.8 1.0
SG D:CYS2614 2.3 107.9 1.0
SG D:CYS2611 2.3 105.1 1.0
CG D:HIS2636 2.9 109.8 1.0
CE1 D:HIS2631 3.0 113.8 1.0
CB D:HIS2636 3.0 109.8 1.0
CD2 D:HIS2631 3.0 113.8 1.0
CA D:CYS2614 3.2 107.9 1.0
CE1 D:HIS2636 3.2 109.8 1.0
CB D:CYS2611 3.6 105.1 1.0
N D:CYS2614 3.6 107.9 1.0
ND1 D:HIS2631 4.1 113.8 1.0
CD2 D:HIS2636 4.1 109.8 1.0
CG D:HIS2631 4.1 113.8 1.0
NE2 D:HIS2636 4.2 109.8 1.0
C D:CYS2614 4.2 107.9 1.0
CA D:HIS2636 4.5 109.8 1.0
N D:GLY2615 4.7 106.4 1.0
O D:HIS2631 4.9 113.8 1.0
C D:ILE2613 4.9 99.1 1.0
CA D:CYS2611 5.0 105.1 1.0

Zinc binding site 3 out of 4 in 7lhe

Go back to Zinc Binding Sites List in 7lhe
Zinc binding site 3 out of 4 in the Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn2806

b:126.2
occ:1.00
CB C:CYS2614 1.7 107.9 1.0
NE2 C:HIS2631 2.0 113.8 1.0
ND1 C:HIS2636 2.1 109.8 1.0
SG C:CYS2614 2.3 107.9 1.0
SG C:CYS2611 2.3 105.1 1.0
CG C:HIS2636 2.9 109.8 1.0
CE1 C:HIS2631 3.0 113.8 1.0
CB C:HIS2636 3.0 109.8 1.0
CD2 C:HIS2631 3.0 113.8 1.0
CA C:CYS2614 3.2 107.9 1.0
CE1 C:HIS2636 3.2 109.8 1.0
CB C:CYS2611 3.6 105.1 1.0
N C:CYS2614 3.6 107.9 1.0
CD2 C:HIS2636 4.1 109.8 1.0
ND1 C:HIS2631 4.1 113.8 1.0
CG C:HIS2631 4.1 113.8 1.0
NE2 C:HIS2636 4.2 109.8 1.0
C C:CYS2614 4.2 107.9 1.0
CA C:HIS2636 4.5 109.8 1.0
N C:GLY2615 4.7 106.4 1.0
O C:HIS2631 4.9 113.8 1.0
C C:ILE2613 4.9 99.1 1.0
CA C:CYS2611 5.0 105.1 1.0

Zinc binding site 4 out of 4 in 7lhe

Go back to Zinc Binding Sites List in 7lhe
Zinc binding site 4 out of 4 in the Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of Full-Length IP3R1 Channel Reconstituted Into Lipid Nanodisc in the Apo-State within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn2809

b:126.2
occ:1.00
CB B:CYS2614 1.7 107.9 1.0
ND1 B:HIS2636 2.0 109.8 1.0
NE2 B:HIS2631 2.0 113.8 1.0
SG B:CYS2614 2.2 107.9 1.0
SG B:CYS2611 2.4 105.1 1.0
CG B:HIS2636 2.8 109.8 1.0
CE1 B:HIS2631 2.9 113.8 1.0
CB B:HIS2636 3.0 109.8 1.0
CD2 B:HIS2631 3.0 113.8 1.0
CE1 B:HIS2636 3.1 109.8 1.0
CA B:CYS2614 3.1 107.9 1.0
N B:CYS2614 3.6 107.9 1.0
CB B:CYS2611 3.7 105.1 1.0
ND1 B:HIS2631 4.0 113.8 1.0
CD2 B:HIS2636 4.0 109.8 1.0
CG B:HIS2631 4.1 113.8 1.0
NE2 B:HIS2636 4.1 109.8 1.0
C B:CYS2614 4.2 107.9 1.0
CA B:HIS2636 4.5 109.8 1.0
N B:GLY2615 4.6 106.4 1.0
O B:HIS2631 4.9 113.8 1.0
C B:ILE2613 4.9 99.1 1.0

Reference:

M.R.Baker, G.Fan, A.B.Seryshev, M.A.Agosto, M.L.Baker, I.I.Serysheva. Cryo-Em Structure of Type 1 IP3R Channel in A Lipid Bilayer Commun Biol V. 4 625 2021.
ISSN: ESSN 2399-3642
DOI: 10.1038/S42003-021-02156-4
Page generated: Mon Jul 12 17:20:50 2021

Last articles

Zn in 7NA9
Zn in 7LZP
Zn in 7M1H
Zn in 7L6V
Zn in 7CM0
V in 7P8R
Ni in 7L19
Na in 7T88
Na in 7MJ5
Na in 7L00
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy