Zinc in PDB 7l91: Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography

All present enzymatic activity of Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography:
3.5.2.6;

The structure of Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography, PDB code: 7l91 was solved by M.Wilamowski, Y.Kim, D.A.Sherrell, A.Lavens, R.Henning, N.Maltseva, M.Endres, G.Babnigg, S.Vukica, A.Joachimiak, Center For Structuralgenomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.03 / 2.20
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	105.853, 105.853, 99.1, 90, 90, 120
R / Rfree (%)	18.1 / 20.8

The binding sites of Zinc atom in the Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography (pdb code 7l91). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography, PDB code: 7l91:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:14.4 occ:0.82 O A:HOH402 1.9 13.8 0.9 NE2 A:HIS181 2.0 26.9 1.0 NE2 A:HIS105 2.1 19.2 1.0 ND1 A:HIS107 2.1 23.8 1.0 O10 A:XQP303 2.2 23.9 1.0 CD2 A:HIS181 2.8 25.8 1.0 CE1 A:HIS105 3.0 17.7 1.0 CE1 A:HIS107 3.1 22.8 1.0 CD2 A:HIS105 3.1 17.1 1.0 CE1 A:HIS181 3.1 27.2 1.0 CG A:HIS107 3.1 22.2 1.0 C1 A:XQP303 3.4 28.5 1.0 CB A:HIS107 3.5 20.9 1.0 O8 A:XQP303 3.5 36.5 1.0 ZN A:ZN302 3.6 13.0 0.8 N1 A:XQP303 3.9 35.8 1.0 CG A:HIS181 4.0 25.2 1.0 O3 A:XQP303 4.0 32.3 1.0 ND1 A:HIS105 4.1 17.2 1.0 ND1 A:HIS181 4.1 26.8 1.0 CD2 A:HIS110 4.1 20.2 1.0 CG A:HIS105 4.1 16.5 1.0 C20 A:XQP303 4.2 36.7 1.0 NE2 A:HIS107 4.2 23.0 1.0 OD1 A:ASP109 4.2 21.5 1.0 NE2 A:HIS110 4.2 22.6 1.0 CD2 A:HIS107 4.2 22.6 1.0 O1 A:XQP303 4.2 26.7 1.0 C6 A:XQP303 4.3 33.2 1.0 C7 A:XQP303 4.4 31.6 1.0 C2 A:XQP303 4.5 37.9 1.0 C5 A:XQP303 4.7 35.1 1.0 CA A:HIS107 4.9 20.9 1.0 OD2 A:ASP109 5.0 24.2 1.0

Zinc binding site 2 out of 2 in the Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:13.0 occ:0.80 NE2 A:HIS110 2.0 22.6 1.0 O A:HOH402 2.2 13.8 0.9 OD2 A:ASP109 2.2 24.2 1.0 NE2 A:HIS246 2.2 19.2 1.0 N1 A:XQP303 2.3 35.8 1.0 O8 A:XQP303 2.4 36.5 1.0 CE1 A:HIS110 2.9 21.7 1.0 CG A:ASP109 3.0 21.8 1.0 CD2 A:HIS110 3.1 20.2 1.0 C2 A:XQP303 3.1 37.9 1.0 C20 A:XQP303 3.1 36.7 1.0 CD2 A:HIS246 3.1 18.5 1.0 OD1 A:ASP109 3.2 21.5 1.0 CE1 A:HIS246 3.3 20.1 1.0 C5 A:XQP303 3.3 35.1 1.0 ZN A:ZN301 3.6 14.4 0.8 O10 A:XQP303 3.9 23.9 1.0 O3 A:XQP303 4.0 32.3 1.0 ND1 A:HIS110 4.0 20.4 1.0 C6 A:XQP303 4.1 33.2 1.0 CG A:HIS110 4.1 19.8 1.0 CE1 A:HIS105 4.1 17.7 1.0 NE2 A:HIS105 4.2 19.2 1.0 C1 A:XQP303 4.2 28.5 1.0 C3 A:XQP303 4.2 42.0 1.0 O9 A:XQP303 4.3 36.4 1.0 CG A:HIS246 4.3 19.1 1.0 ND1 A:HIS246 4.3 20.5 1.0 O2 A:XQP303 4.4 37.5 1.0 CB A:ASP109 4.4 20.8 1.0 OG A:SER206 4.6 26.6 1.0 NE2 A:HIS181 4.7 26.9 1.0 C4 A:XQP303 4.9 39.4 1.0

M.Wilamowski, Y.Kim, D.A.Sherrell, A.Lavens, R.Henning, N.Maltseva, M.Endres, G.Babnigg, S.Vukica, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Structure of Metallo Beta-Lactamase L1 in A Complex with Hydrolyzed Moxalactam Determined By Pink-Beam Serial Crystallography To Be Published.