Zinc in PDB 7joa: 2:1 Cgas-Nucleosome Complex

All present enzymatic activity of 2:1 Cgas-Nucleosome Complex:
2.7.7.86;

The binding sites of Zinc atom in the 2:1 Cgas-Nucleosome Complex (pdb code 7joa). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the 2:1 Cgas-Nucleosome Complex, PDB code: 7joa:

Zinc binding site 1 out of 1 in the 2:1 Cgas-Nucleosome Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of 2:1 Cgas-Nucleosome Complex within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn601 b:0.8 occ:1.00 SG K:CYS385 2.3 83.3 1.0 SG K:CYS392 2.3 87.8 1.0 NE2 K:HIS378 2.3 80.1 1.0 CD2 K:HIS378 2.7 80.1 1.0 NH1 K:ARG394 2.8 87.2 1.0 SG K:CYS384 2.8 90.9 1.0 CE1 K:HIS378 3.4 80.1 1.0 CB K:CYS392 3.5 87.8 1.0 CB K:CYS385 3.6 83.3 1.0 CG K:HIS378 3.9 80.1 1.0 CZ K:ARG394 4.1 87.2 1.0 ND1 K:HIS378 4.2 80.1 1.0 N K:CYS385 4.2 83.3 1.0 N K:CYS392 4.3 87.8 1.0 CB K:CYS384 4.3 90.9 1.0 CD K:ARG394 4.4 87.2 1.0 C K:CYS384 4.4 90.9 1.0 CA K:CYS392 4.5 87.8 1.0 CA K:CYS385 4.5 83.3 1.0 NE K:ARG394 4.7 87.2 1.0 O K:CYS384 4.7 90.9 1.0 CG K:ARG394 4.8 87.2 1.0 CA K:CYS384 4.9 90.9 1.0 CB K:ARG394 5.0 87.2 1.0

J.A.Boyer, C.J.Spangler, J.D.Strauss, A.P.Cesmat, P.Liu, R.K.Mcginty, Q.Zhang. Structural Basis of Nucleosome-Dependent Cgas Inhibition. Science V. 370 450 2020.
ISSN: ESSN 1095-9203
PubMed: 32913000
DOI: 10.1126/SCIENCE.ABD0609