Zinc in PDB 7jo9: 1:1 Cgas-Nucleosome Complex

All present enzymatic activity of 1:1 Cgas-Nucleosome Complex:
2.7.7.86;

The binding sites of Zinc atom in the 1:1 Cgas-Nucleosome Complex (pdb code 7jo9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the 1:1 Cgas-Nucleosome Complex, PDB code: 7jo9:

Zinc binding site 1 out of 1 in the 1:1 Cgas-Nucleosome Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of 1:1 Cgas-Nucleosome Complex within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn601 b:0.8 occ:1.00 SG K:CYS385 2.0 87.5 1.0 NE2 K:HIS378 2.1 88.1 1.0 SG K:CYS392 2.4 89.3 1.0 SG K:CYS384 2.8 84.5 1.0 CD2 K:HIS378 3.0 88.1 1.0 CE1 K:HIS378 3.0 88.1 1.0 CB K:CYS385 3.3 87.5 1.0 CB K:CYS392 3.5 89.3 1.0 N K:CYS392 3.9 89.3 1.0 N K:CYS385 4.0 87.5 1.0 ND1 K:HIS378 4.1 88.1 1.0 CG K:HIS378 4.1 88.1 1.0 CA K:CYS385 4.2 87.5 1.0 CB K:CYS384 4.2 84.5 1.0 C K:CYS384 4.2 84.5 1.0 CA K:CYS392 4.2 89.3 1.0 NH1 K:ARG394 4.3 89.0 1.0 O K:CYS384 4.6 84.5 1.0 O K:ALA390 4.6 77.2 1.0 CA K:CYS384 4.7 84.5 1.0 C K:LYS391 4.7 86.2 1.0 C K:CYS392 4.9 89.3 1.0

J.A.Boyer, C.J.Spangler, J.D.Strauss, A.P.Cesmat, P.Liu, R.K.Mcginty, Q.Zhang. Structural Basis of Nucleosome-Dependent Cgas Inhibition. Science V. 370 450 2020.
ISSN: ESSN 1095-9203
PubMed: 32913000
DOI: 10.1126/SCIENCE.ABD0609