|
Atomistry » Zinc » PDB 7jiw-7jv8 » 7jnv | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 7jiw-7jv8 » 7jnv » |
Zinc in PDB 7jnv: Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)ButyramideEnzymatic activity of Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Butyramide
All present enzymatic activity of Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Butyramide:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Butyramide, PDB code: 7jnv
was solved by
J.T.Andring,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Butyramide
(pdb code 7jnv). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Butyramide, PDB code: 7jnv: Zinc binding site 1 out of 1 in 7jnvGo back to Zinc Binding Sites List in 7jnv
Zinc binding site 1 out
of 1 in the Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Butyramide
Mono view Stereo pair view
Reference:
J.T.Andring,
M.Fouch,
S.Akocak,
A.Angeli,
C.T.Supuran,
M.A.Ilies,
R.Mckenna.
Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone. J.Med.Chem. V. 63 13064 2020.
Page generated: Tue Oct 29 21:00:29 2024
ISSN: ISSN 0022-2623 PubMed: 33085484 DOI: 10.1021/ACS.JMEDCHEM.0C01390 |
Last articlesZn in 7Z78Zn in 7Z31 Zn in 7Z71 Zn in 7Z7E Zn in 7Z5H Zn in 7Z70 Zn in 7Z6Z Zn in 7Z6S Zn in 7Z68 Zn in 7Z5U |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |