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Zinc in PDB 7jnr: Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)PropionamideEnzymatic activity of Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Propionamide
All present enzymatic activity of Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Propionamide:
4.2.1.1; Protein crystallography data
The structure of Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Propionamide, PDB code: 7jnr
was solved by
J.T.Andring,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Propionamide
(pdb code 7jnr). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Propionamide, PDB code: 7jnr: Zinc binding site 1 out of 1 in 7jnrGo back to Zinc Binding Sites List in 7jnr
Zinc binding site 1 out
of 1 in the Carbonic Anhydrase II Complexed with N-(5-Sulfamoyl-1,3,4-Thiadiazol- 2-Yl)Propionamide
Mono view Stereo pair view
Reference:
J.T.Andring,
M.Fouch,
S.Akocak,
A.Angeli,
C.T.Supuran,
M.A.Ilies,
R.Mckenna.
Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone. J.Med.Chem. V. 63 13064 2020.
Page generated: Wed Dec 16 13:46:14 2020
ISSN: ISSN 0022-2623 PubMed: 33085484 DOI: 10.1021/ACS.JMEDCHEM.0C01390 |
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