Atomistry » Zinc » PDB 7hl3-7jo0 » 7hog
Atomistry »
  Zinc »
    PDB 7hl3-7jo0 »
      7hog »

Zinc in PDB 7hog: Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1216861874 (A71EV2A-X0525)

Enzymatic activity of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1216861874 (A71EV2A-X0525)

All present enzymatic activity of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1216861874 (A71EV2A-X0525):
3.4.22.29;

Protein crystallography data

The structure of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1216861874 (A71EV2A-X0525), PDB code: 7hog was solved by R.M.Lithgo, M.Fairhead, L.Koekemoer, B.H.Balcomb, E.Capkin, A.V.Chandran, M.Golding, A.S.Godoy, J.C.Aschenbrenner, P.G.Marples, X.Ni, W.Thompson, C.W.E.Tomlinson, C.Wild, M.Winokan, M.-A.E.Xavier, D.Fearon, F.Von Delft, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.20 / 1.19
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 86.088, 56.539, 32.421, 90, 95.26, 90
R / Rfree (%) 17 / 18.7

Other elements in 7hog:

The structure of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1216861874 (A71EV2A-X0525) also contains other interesting chemical elements:

Fluorine (F) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1216861874 (A71EV2A-X0525) (pdb code 7hog). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1216861874 (A71EV2A-X0525), PDB code: 7hog:

Zinc binding site 1 out of 1 in 7hog

Go back to Zinc Binding Sites List in 7hog
Zinc binding site 1 out of 1 in the Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1216861874 (A71EV2A-X0525)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease -- Crystal Structure of Coxsackievirus A16 (G-10) 2A Protease in Complex with Z1216861874 (A71EV2A-X0525) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn202

b:11.4
occ:1.00
 ND1 A:HIS118 2.1 11.8 1.0
SG A:CYS116 2.3 10.8 1.0
SG A:CYS58 2.3 12.5 1.0
SG A:CYS56 2.3 11.2 1.0
CE1 A:HIS118 3.0 12.0 1.0
CG A:HIS118 3.1 11.7 1.0
CB A:CYS58 3.2 13.1 1.0
CB A:CYS56 3.2 10.2 1.0
CB A:CYS116 3.3 10.5 1.0
CB A:HIS118 3.5 11.3 1.0
N A:HIS118 3.9 12.6 1.0
NE2 A:HIS118 4.1 14.1 1.0
CD2 A:HIS118 4.2 13.5 1.0
N A:CYS58 4.2 11.9 1.0
CA A:CYS58 4.2 11.2 1.0
CA A:HIS118 4.3 11.9 1.0
CG A:GLN117 4.4 17.1 1.0
CB A:ALA54 4.4 11.3 1.0
N A:GLN117 4.5 12.9 1.0
CA A:CYS116 4.6 10.9 1.0
CA A:CYS56 4.7 10.8 1.0
O A:HOH489 4.7 20.2 1.0
C A:CYS116 4.8 10.5 1.0
C A:GLN117 4.9 13.7 1.0

Reference:

R.M.Lithgo, M.Fairhead, L.Koekemoer, B.H.Balcomb, E.Capkin, A.V.Chandran, M.Golding, A.S.Godoy, J.C.Aschenbrenner, P.G.Marples, X.Ni, W.Thompson, C.W.E.Tomlinson, C.Wild, M.Winokan, M.-A.E.Xavier, D.Fearon, F.Von Delft. Group Deposition For Crystallographic Fragment Screening of Coxsackievirus A16 (G-10) 2A Protease To Be Published.
Page generated: Sun Feb 9 00:41:23 2025

Last articles

Zn in 9IRQ
Zn in 9IYX
Zn in 9J8P
Zn in 9IUU
Zn in 9GBF
Zn in 9G2V
Zn in 9G2L
Zn in 9G2X
Zn in 9G2Z
Zn in 9G2K
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy