Zinc in PDB 7fjj: Human Pol III Pre-Termination Complex
Enzymatic activity of Human Pol III Pre-Termination Complex
All present enzymatic activity of Human Pol III Pre-Termination Complex:
2.7.7.6;
Other elements in 7fjj:
The structure of Human Pol III Pre-Termination Complex also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Pol III Pre-Termination Complex
(pdb code 7fjj). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 7 binding sites of Zinc where determined in the
Human Pol III Pre-Termination Complex, PDB code: 7fjj:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
Zinc binding site 1 out
of 7 in 7fjj
Go back to
Zinc Binding Sites List in 7fjj
Zinc binding site 1 out
of 7 in the Human Pol III Pre-Termination Complex
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Human Pol III Pre-Termination Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1902
b:109.9
occ:1.00
|
NE2
|
A:HIS82
|
2.3
|
84.0
|
1.0
|
SG
|
A:CYS69
|
2.3
|
96.0
|
1.0
|
SG
|
A:CYS79
|
2.3
|
88.7
|
1.0
|
SG
|
A:CYS72
|
2.3
|
94.5
|
1.0
|
CE1
|
A:HIS82
|
3.2
|
84.0
|
1.0
|
CD2
|
A:HIS82
|
3.3
|
84.0
|
1.0
|
CB
|
A:CYS79
|
3.4
|
88.7
|
1.0
|
CB
|
A:CYS69
|
3.5
|
96.0
|
1.0
|
CB
|
A:CYS72
|
3.7
|
94.5
|
1.0
|
CA
|
A:CYS79
|
4.0
|
88.7
|
1.0
|
N
|
A:CYS72
|
4.0
|
94.5
|
1.0
|
OG1
|
A:THR71
|
4.2
|
92.6
|
1.0
|
CA
|
A:CYS72
|
4.3
|
94.5
|
1.0
|
ND1
|
A:HIS82
|
4.3
|
84.0
|
1.0
|
CG
|
A:HIS82
|
4.4
|
84.0
|
1.0
|
O
|
A:CYS72
|
4.5
|
94.5
|
1.0
|
CB
|
A:LYS74
|
4.5
|
89.0
|
1.0
|
C
|
A:CYS72
|
4.6
|
94.5
|
1.0
|
N
|
A:LEU80
|
4.6
|
84.7
|
1.0
|
O
|
A:LYS74
|
4.7
|
89.0
|
1.0
|
C
|
A:CYS79
|
4.8
|
88.7
|
1.0
|
N
|
A:LYS74
|
4.8
|
89.0
|
1.0
|
CA
|
A:CYS69
|
4.9
|
96.0
|
1.0
|
|
Zinc binding site 2 out
of 7 in 7fjj
Go back to
Zinc Binding Sites List in 7fjj
Zinc binding site 2 out
of 7 in the Human Pol III Pre-Termination Complex
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Human Pol III Pre-Termination Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1903
b:140.3
occ:1.00
|
SG
|
A:CYS159
|
1.5
|
121.4
|
1.0
|
SG
|
A:CYS109
|
2.5
|
104.6
|
1.0
|
SG
|
A:CYS112
|
3.0
|
105.2
|
1.0
|
CB
|
A:CYS159
|
3.2
|
121.4
|
1.0
|
SG
|
A:CYS156
|
3.3
|
118.4
|
1.0
|
N
|
A:CYS159
|
3.4
|
121.4
|
1.0
|
CB
|
A:CYS109
|
3.4
|
104.6
|
1.0
|
CB
|
A:CYS156
|
3.5
|
118.4
|
1.0
|
CB
|
A:ALA161
|
3.7
|
117.2
|
1.0
|
CB
|
A:CYS112
|
3.7
|
105.2
|
1.0
|
CA
|
A:CYS159
|
3.8
|
121.4
|
1.0
|
N
|
A:ALA161
|
3.9
|
117.2
|
1.0
|
CB
|
A:HIS158
|
4.1
|
119.3
|
1.0
|
N
|
A:GLY160
|
4.1
|
118.5
|
1.0
|
C
|
A:CYS159
|
4.2
|
121.4
|
1.0
|
N
|
A:CYS112
|
4.3
|
105.2
|
1.0
|
C
|
A:HIS158
|
4.3
|
119.3
|
1.0
|
CA
|
A:ALA161
|
4.4
|
117.2
|
1.0
|
CA
|
A:CYS112
|
4.6
|
105.2
|
1.0
|
OD1
|
A:ASN163
|
4.6
|
112.6
|
1.0
|
CA
|
A:HIS158
|
4.7
|
119.3
|
1.0
|
CA
|
A:CYS109
|
4.8
|
104.6
|
1.0
|
O
|
A:ALA161
|
4.8
|
117.2
|
1.0
|
N
|
A:HIS158
|
4.9
|
119.3
|
1.0
|
CA
|
A:CYS156
|
5.0
|
118.4
|
1.0
|
C
|
A:GLY160
|
5.0
|
118.5
|
1.0
|
|
Zinc binding site 3 out
of 7 in 7fjj
Go back to
Zinc Binding Sites List in 7fjj
Zinc binding site 3 out
of 7 in the Human Pol III Pre-Termination Complex
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Human Pol III Pre-Termination Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn1201
b:95.5
occ:1.00
|
SG
|
B:CYS1083
|
1.9
|
81.5
|
1.0
|
SG
|
B:CYS1080
|
2.3
|
81.6
|
1.0
|
SG
|
B:CYS1092
|
2.3
|
86.5
|
1.0
|
SG
|
B:CYS1095
|
2.4
|
88.1
|
1.0
|
CB
|
B:CYS1080
|
2.7
|
81.6
|
1.0
|
CB
|
B:CYS1092
|
3.1
|
86.5
|
1.0
|
CB
|
B:CYS1083
|
3.6
|
81.5
|
1.0
|
CB
|
B:CYS1095
|
3.8
|
88.1
|
1.0
|
CA
|
B:CYS1080
|
4.1
|
81.6
|
1.0
|
N
|
B:CYS1095
|
4.3
|
88.1
|
1.0
|
O
|
B:CYS1095
|
4.4
|
88.1
|
1.0
|
CA
|
B:CYS1092
|
4.5
|
86.5
|
1.0
|
O
|
B:LEU1085
|
4.6
|
77.4
|
1.0
|
N
|
B:CYS1083
|
4.6
|
81.5
|
1.0
|
CG
|
B:GLN1082
|
4.7
|
83.6
|
1.0
|
CA
|
B:CYS1083
|
4.7
|
81.5
|
1.0
|
CA
|
B:CYS1095
|
4.8
|
88.1
|
1.0
|
N
|
B:CYS1080
|
4.8
|
81.6
|
1.0
|
CB
|
B:TYR1094
|
4.9
|
85.8
|
1.0
|
NE2
|
B:GLN1082
|
4.9
|
83.6
|
1.0
|
C
|
B:CYS1080
|
4.9
|
81.6
|
1.0
|
|
Zinc binding site 4 out
of 7 in 7fjj
Go back to
Zinc Binding Sites List in 7fjj
Zinc binding site 4 out
of 7 in the Human Pol III Pre-Termination Complex
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Human Pol III Pre-Termination Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn201
b:196.5
occ:1.00
|
CB
|
I:ASN99
|
2.8
|
191.9
|
1.0
|
SG
|
I:CYS72
|
3.1
|
186.9
|
1.0
|
SG
|
I:CYS102
|
3.2
|
191.3
|
1.0
|
N
|
I:ASN99
|
3.2
|
191.9
|
1.0
|
SG
|
I:CYS97
|
3.5
|
189.3
|
1.0
|
CA
|
I:ASN99
|
3.6
|
191.9
|
1.0
|
C
|
I:CYS98
|
3.7
|
190.6
|
1.0
|
CB
|
I:CYS97
|
3.7
|
189.3
|
1.0
|
N
|
I:CYS98
|
3.8
|
190.6
|
1.0
|
CB
|
I:CYS102
|
3.9
|
191.3
|
1.0
|
C
|
I:CYS97
|
3.9
|
189.3
|
1.0
|
O
|
I:CYS102
|
4.0
|
191.3
|
1.0
|
CG
|
I:ASN99
|
4.0
|
191.9
|
1.0
|
CA
|
I:CYS98
|
4.1
|
190.6
|
1.0
|
ND2
|
I:ASN99
|
4.2
|
191.9
|
1.0
|
O
|
I:CYS97
|
4.3
|
189.3
|
1.0
|
CB
|
I:CYS72
|
4.4
|
186.9
|
1.0
|
CA
|
I:CYS97
|
4.4
|
189.3
|
1.0
|
O
|
I:CYS98
|
4.4
|
190.6
|
1.0
|
O
|
I:ARG76
|
4.5
|
186.6
|
1.0
|
C
|
I:ASN99
|
4.6
|
191.9
|
1.0
|
C
|
I:CYS102
|
4.6
|
191.3
|
1.0
|
O
|
I:ASN99
|
4.9
|
191.9
|
1.0
|
CA
|
I:CYS102
|
4.9
|
191.3
|
1.0
|
|
Zinc binding site 5 out
of 7 in 7fjj
Go back to
Zinc Binding Sites List in 7fjj
Zinc binding site 5 out
of 7 in the Human Pol III Pre-Termination Complex
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Human Pol III Pre-Termination Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn202
b:88.2
occ:1.00
|
SG
|
I:CYS5
|
2.4
|
79.0
|
1.0
|
SG
|
I:CYS25
|
2.5
|
86.2
|
1.0
|
SG
|
I:CYS28
|
2.5
|
87.3
|
1.0
|
SG
|
I:CYS8
|
2.5
|
77.8
|
1.0
|
CB
|
I:CYS5
|
2.8
|
79.0
|
1.0
|
CB
|
I:CYS25
|
3.0
|
86.2
|
1.0
|
CB
|
I:CYS28
|
3.7
|
87.3
|
1.0
|
CB
|
I:CYS8
|
4.0
|
77.8
|
1.0
|
N
|
I:CYS8
|
4.0
|
77.8
|
1.0
|
CA
|
I:CYS5
|
4.3
|
79.0
|
1.0
|
OG1
|
I:THR27
|
4.4
|
84.5
|
1.0
|
CA
|
I:CYS8
|
4.4
|
77.8
|
1.0
|
CA
|
I:CYS25
|
4.5
|
86.2
|
1.0
|
N
|
I:CYS28
|
4.5
|
87.3
|
1.0
|
N
|
I:GLY9
|
4.6
|
76.9
|
1.0
|
CB
|
I:TYR30
|
4.6
|
87.0
|
1.0
|
CA
|
I:CYS28
|
4.6
|
87.3
|
1.0
|
N
|
I:ASN10
|
4.7
|
77.4
|
1.0
|
C
|
I:CYS8
|
4.9
|
77.8
|
1.0
|
C
|
I:CYS5
|
4.9
|
79.0
|
1.0
|
CB
|
I:ASN10
|
4.9
|
77.4
|
1.0
|
|
Zinc binding site 6 out
of 7 in 7fjj
Go back to
Zinc Binding Sites List in 7fjj
Zinc binding site 6 out
of 7 in the Human Pol III Pre-Termination Complex
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Human Pol III Pre-Termination Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn2000
b:30.0
occ:1.00
|
SG
|
J:CYS10
|
1.4
|
57.9
|
1.0
|
SG
|
J:CYS44
|
2.3
|
57.1
|
1.0
|
SG
|
J:CYS7
|
2.3
|
54.0
|
1.0
|
SG
|
J:CYS45
|
2.3
|
54.9
|
1.0
|
N
|
J:CYS45
|
2.8
|
54.9
|
1.0
|
CB
|
J:CYS10
|
3.0
|
57.9
|
1.0
|
CB
|
J:CYS44
|
3.2
|
57.1
|
1.0
|
CA
|
J:CYS45
|
3.3
|
54.9
|
1.0
|
C
|
J:CYS44
|
3.3
|
57.1
|
1.0
|
CB
|
J:CYS7
|
3.3
|
54.0
|
1.0
|
CB
|
J:CYS45
|
3.4
|
54.9
|
1.0
|
CA
|
J:CYS44
|
3.8
|
57.1
|
1.0
|
N
|
J:CYS10
|
3.8
|
57.9
|
1.0
|
CA
|
J:CYS10
|
4.0
|
57.9
|
1.0
|
O
|
J:CYS44
|
4.0
|
57.1
|
1.0
|
OG1
|
J:THR9
|
4.5
|
55.0
|
1.0
|
CD
|
J:ARG42
|
4.5
|
58.8
|
1.0
|
CG
|
J:ARG42
|
4.6
|
58.8
|
1.0
|
N
|
J:CYS44
|
4.6
|
57.1
|
1.0
|
CA
|
J:CYS7
|
4.7
|
54.0
|
1.0
|
C
|
J:CYS45
|
4.8
|
54.9
|
1.0
|
N
|
J:GLY11
|
4.8
|
55.5
|
1.0
|
C
|
J:CYS10
|
4.9
|
57.9
|
1.0
|
|
Zinc binding site 7 out
of 7 in 7fjj
Go back to
Zinc Binding Sites List in 7fjj
Zinc binding site 7 out
of 7 in the Human Pol III Pre-Termination Complex
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Human Pol III Pre-Termination Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
L:Zn101
b:98.6
occ:1.00
|
CB
|
L:CYS22
|
2.0
|
85.9
|
1.0
|
SG
|
L:CYS19
|
2.3
|
81.3
|
1.0
|
SG
|
L:CYS39
|
2.3
|
98.0
|
1.0
|
CB
|
L:CYS19
|
3.1
|
81.3
|
1.0
|
CA
|
L:CYS22
|
3.1
|
85.9
|
1.0
|
N
|
L:CYS22
|
3.1
|
85.9
|
1.0
|
CB
|
L:CYS39
|
3.4
|
98.0
|
1.0
|
SG
|
L:CYS22
|
3.4
|
85.9
|
1.0
|
OG1
|
L:THR24
|
3.8
|
83.6
|
1.0
|
C
|
L:CYS22
|
4.0
|
85.9
|
1.0
|
OE2
|
L:GLU21
|
4.0
|
84.8
|
1.0
|
CB
|
L:CYS36
|
4.0
|
93.2
|
1.0
|
N
|
L:HIS23
|
4.0
|
83.8
|
1.0
|
CA
|
L:CYS19
|
4.4
|
81.3
|
1.0
|
C
|
L:GLU21
|
4.4
|
84.8
|
1.0
|
O
|
L:ARG37
|
4.5
|
95.1
|
1.0
|
SG
|
L:CYS36
|
4.6
|
93.2
|
1.0
|
N
|
L:THR24
|
4.6
|
83.6
|
1.0
|
CA
|
L:CYS39
|
4.7
|
98.0
|
1.0
|
N
|
L:CYS39
|
4.8
|
98.0
|
1.0
|
C
|
L:CYS19
|
4.8
|
81.3
|
1.0
|
N
|
L:GLU21
|
4.8
|
84.8
|
1.0
|
ND2
|
L:ASN26
|
4.9
|
87.2
|
1.0
|
CB
|
L:TYR41
|
4.9
|
95.7
|
1.0
|
O
|
L:CYS22
|
5.0
|
85.9
|
1.0
|
|
Reference:
H.Hou,
Y.Xu.
Human Pol III Pre-Termination Complex To Be Published.
Page generated: Tue Oct 29 20:31:53 2024
|