Zinc in PDB 7ef9: Crystal Structure of Mouse Mutyh in Complex with Dna Containing Ap Site Analogue:8-Oxog (Form II)

Enzymatic activity of Crystal Structure of Mouse Mutyh in Complex with Dna Containing Ap Site Analogue:8-Oxog (Form II)

All present enzymatic activity of Crystal Structure of Mouse Mutyh in Complex with Dna Containing Ap Site Analogue:8-Oxog (Form II):
3.2.2.31;

Protein crystallography data

The structure of Crystal Structure of Mouse Mutyh in Complex with Dna Containing Ap Site Analogue:8-Oxog (Form II), PDB code: 7ef9 was solved by T.Nakamura, Y.Nakabeppu, Y.Yamagata, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.53 / 1.97
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 71.66, 108.496, 158.527, 90, 90, 90
R / Rfree (%) 17.8 / 19.7

Other elements in 7ef9:

The structure of Crystal Structure of Mouse Mutyh in Complex with Dna Containing Ap Site Analogue:8-Oxog (Form II) also contains other interesting chemical elements:

Iron (Fe) 4 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Mouse Mutyh in Complex with Dna Containing Ap Site Analogue:8-Oxog (Form II) (pdb code 7ef9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Mouse Mutyh in Complex with Dna Containing Ap Site Analogue:8-Oxog (Form II), PDB code: 7ef9:

Zinc binding site 1 out of 1 in 7ef9

Go back to Zinc Binding Sites List in 7ef9
Zinc binding site 1 out of 1 in the Crystal Structure of Mouse Mutyh in Complex with Dna Containing Ap Site Analogue:8-Oxog (Form II)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mouse Mutyh in Complex with Dna Containing Ap Site Analogue:8-Oxog (Form II) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn502

b:57.8
occ:0.90
 NE2 A:HIS56 2.1 60.9 1.0
SG A:CYS300 2.4 63.5 1.0
CE1 A:HIS56 3.1 56.5 1.0
CD2 A:HIS56 3.1 57.4 1.0
CB A:CYS300 3.1 65.5 1.0
ND1 A:HIS56 4.2 54.6 1.0
CB A:ASN303 4.2 67.5 1.0
CG A:HIS56 4.2 61.6 1.0
OG A:SER53 4.3 74.3 1.0
CG A:ASN303 4.6 58.6 1.0
CA A:CYS300 4.6 71.1 1.0
CD2 A:TYR55 4.7 61.0 1.0
OD1 A:ASN303 4.8 60.5 1.0
O A:HOH737 4.8 51.1 1.0
CA A:ASN303 5.0 70.6 1.0
N A:ASN303 5.0 79.0 1.0

Reference:

T.Nakamura, K.Okabe, S.Hirayama, M.Chirifu, S.Ikemizu, H.Morioka, Y.Nakabeppu, Y.Yamagata. Structure of the Mammalian Adenine Dna Glycosylase Mutyh: Insights Into the Base Excision Repair Pathway and Cancer. Nucleic Acids Res. 2021.
ISSN: ESSN 1362-4962
DOI: 10.1093/NAR/GKAB492
Page generated: Mon Jul 12 17:03:36 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy