Zinc in PDB 7dte: Sars-Cov-2 Rdrp Catalytic Complex with T33-1 Rna

All present enzymatic activity of Sars-Cov-2 Rdrp Catalytic Complex with T33-1 Rna:
2.7.7.48;

The binding sites of Zinc atom in the Sars-Cov-2 Rdrp Catalytic Complex with T33-1 Rna (pdb code 7dte). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sars-Cov-2 Rdrp Catalytic Complex with T33-1 Rna, PDB code: 7dte:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sars-Cov-2 Rdrp Catalytic Complex with T33-1 Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Rdrp Catalytic Complex with T33-1 Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:40.3 occ:1.00 SG A:CYS310 2.3 19.8 1.0 SG A:CYS306 2.3 18.8 1.0 SG A:CYS301 2.3 20.6 1.0 ND1 A:HIS295 2.5 24.0 1.0 O A:CYS306 3.0 18.8 1.0 CB A:CYS301 3.3 20.6 1.0 CB A:CYS306 3.3 18.8 1.0 CE1 A:HIS295 3.4 24.0 1.0 C A:CYS306 3.4 18.8 1.0 CB A:CYS310 3.6 19.8 1.0 CG A:HIS295 3.6 24.0 1.0 CA A:CYS301 3.8 20.6 1.0 CA A:CYS306 3.8 18.8 1.0 CB A:HIS295 3.9 24.0 1.0 N A:ILE307 4.2 14.8 1.0 N A:HIS295 4.5 24.0 1.0 NE2 A:HIS295 4.6 24.0 1.0 N A:CYS310 4.6 19.8 1.0 N A:CYS301 4.7 20.6 1.0 CA A:ILE307 4.7 14.8 1.0 CD2 A:HIS295 4.7 24.0 1.0 CA A:CYS310 4.7 19.8 1.0 N A:LEU302 4.8 23.3 1.0 O A:THR293 4.8 21.7 1.0 CA A:HIS295 4.8 24.0 1.0 C A:CYS301 4.9 20.6 1.0

Zinc binding site 2 out of 2 in the Sars-Cov-2 Rdrp Catalytic Complex with T33-1 Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Cov-2 Rdrp Catalytic Complex with T33-1 Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:38.6 occ:1.00 ND1 A:HIS642 2.1 19.0 1.0 SG A:CYS487 2.3 17.2 1.0 SG A:CYS645 2.3 24.1 1.0 SG A:CYS646 2.4 21.7 1.0 CG A:HIS642 2.9 19.0 1.0 CB A:HIS642 3.0 19.0 1.0 CE1 A:HIS642 3.2 19.0 1.0 CB A:CYS646 3.5 21.7 1.0 CB A:CYS645 3.5 24.1 1.0 CB A:CYS487 3.7 17.2 1.0 N A:CYS646 3.8 21.7 1.0 N A:CYS487 3.9 17.2 1.0 C A:CYS645 4.1 24.1 1.0 CA A:HIS642 4.1 19.0 1.0 CD2 A:HIS642 4.1 19.0 1.0 CE1 A:PHE571 4.1 13.2 1.0 CA A:CYS646 4.2 21.7 1.0 NE2 A:HIS642 4.2 19.0 1.0 CA A:CYS645 4.3 24.1 1.0 CA A:CYS487 4.4 17.2 1.0 CD1 A:PHE571 4.6 13.2 1.0 C A:GLY486 4.7 15.3 1.0 O A:CYS645 4.7 24.1 1.0 N A:CYS645 4.8 24.1 1.0 O A:HIS642 4.9 19.0 1.0 C A:HIS642 4.9 19.0 1.0 CA A:GLY486 4.9 15.3 1.0 CZ A:PHE571 5.0 13.2 1.0

Q.Wang, P.Gong. Sars-Cov-2 Rdrp Catalytic Complex with T33-1 Rna To Be Published.