Zinc in PDB 7doi: Structure of Covid-19 Rna-Dependent Rna Polymerase Bound to Penciclovir.

All present enzymatic activity of Structure of Covid-19 Rna-Dependent Rna Polymerase Bound to Penciclovir.:
2.7.7.48;

The structure of Structure of Covid-19 Rna-Dependent Rna Polymerase Bound to Penciclovir. also contains other interesting chemical elements:

Magnesium

(Mg)

4 atoms

The binding sites of Zinc atom in the Structure of Covid-19 Rna-Dependent Rna Polymerase Bound to Penciclovir. (pdb code 7doi). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Covid-19 Rna-Dependent Rna Polymerase Bound to Penciclovir., PDB code: 7doi:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Covid-19 Rna-Dependent Rna Polymerase Bound to Penciclovir.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Covid-19 Rna-Dependent Rna Polymerase Bound to Penciclovir. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:44.3 occ:1.00 ND1 A:HIS295 2.2 27.2 1.0 SG A:CYS310 2.4 24.1 1.0 SG A:CYS306 2.4 28.1 1.0 SG A:CYS301 2.5 31.3 1.0 CE1 A:HIS295 2.9 27.2 1.0 O A:CYS306 3.2 28.1 1.0 CG A:HIS295 3.3 27.2 1.0 CB A:CYS301 3.5 31.3 1.0 CB A:CYS306 3.6 28.1 1.0 CB A:CYS310 3.7 24.1 1.0 C A:CYS306 3.8 28.1 1.0 CA A:CYS301 3.8 31.3 1.0 CB A:HIS295 3.9 27.2 1.0 CA A:CYS306 4.1 28.1 1.0 NE2 A:HIS295 4.1 27.2 1.0 N A:HIS295 4.2 27.2 1.0 CD2 A:HIS295 4.3 27.2 1.0 O A:THR293 4.4 27.2 1.0 N A:ILE307 4.7 24.8 1.0 CA A:HIS295 4.7 27.2 1.0 ND1 A:HIS309 4.7 23.6 1.0 N A:LEU302 4.7 32.7 1.0 N A:CYS301 4.8 31.3 1.0 N A:CYS310 4.8 24.1 1.0 CA A:CYS310 4.9 24.1 1.0 C A:CYS301 4.9 31.3 1.0

Zinc binding site 2 out of 2 in the Structure of Covid-19 Rna-Dependent Rna Polymerase Bound to Penciclovir.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Covid-19 Rna-Dependent Rna Polymerase Bound to Penciclovir. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:50.1 occ:1.00 CD2 A:HIS642 2.4 34.1 1.0 SG A:CYS487 2.5 33.0 1.0 SG A:CYS646 2.5 38.0 1.0 SG A:CYS645 2.5 39.2 1.0 CG A:HIS642 3.1 34.1 1.0 CB A:HIS642 3.4 34.1 1.0 NE2 A:HIS642 3.5 34.1 1.0 CB A:CYS645 3.5 39.2 1.0 CB A:CYS646 3.5 38.0 1.0 CB A:CYS487 3.6 33.0 1.0 N A:CYS487 3.8 33.0 1.0 C A:CYS645 3.9 39.2 1.0 N A:CYS646 4.0 38.0 1.0 CA A:HIS642 4.2 34.1 1.0 CE1 A:PHE571 4.2 30.8 1.0 CA A:CYS487 4.2 33.0 1.0 O A:CYS645 4.2 39.2 1.0 CA A:CYS646 4.3 38.0 1.0 CA A:CYS645 4.3 39.2 1.0 NZ A:LYS532 4.4 30.8 1.0 ND1 A:HIS642 4.4 34.1 1.0 CE1 A:HIS642 4.5 34.1 1.0 O A:HIS642 4.6 34.1 1.0 C A:GLY486 4.6 30.6 1.0 CD1 A:PHE571 4.7 30.8 1.0 CA A:GLY486 4.8 30.6 1.0 C A:HIS642 4.8 34.1 1.0 CE A:LYS532 4.9 30.8 1.0 N A:CYS645 4.9 39.2 1.0 CZ A:PHE571 5.0 30.8 1.0

W.Yin, X.Luan, Z.Li, Y.Xie, Z.Zhou, J.Liu, M.Gao, X.Wang, F.Zhou, Q.Wang, Q.Wang, D.Shen, Y.Zhang, G.Tian, H.Aisa, D.Wei, Y.Jiang, G.Xiao, H.Jiang, L.Zhang, X.Yu, J.Shen, S.Zhang, H.Xu. Structural Basis For Repurpose and Design of Nucleotide Drugs For Treating Covid-19 To Be Published.