Zinc in PDB 7dh8: Crystal Structure of Holo Xczur

The structure of Crystal Structure of Holo Xczur, PDB code: 7dh8 was solved by F.M.Liu, Z.H.Su, P.Chen, X.L.Tian, L.J.Wu, D.J.Tang, P.F.Li, H.T.Deng, J.L.Tang, Z.H.Ming, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.57 / 1.85
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	34.56, 122.9, 86.89, 90, 90, 90
R / Rfree (%)	21.3 / 25.2

The binding sites of Zinc atom in the Crystal Structure of Holo Xczur (pdb code 7dh8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Holo Xczur, PDB code: 7dh8:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Holo Xczur


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Holo Xczur within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:34.0 occ:1.00 NE2 A:HIS98 2.0 31.0 1.0 OE2 A:GLU132 2.0 34.7 1.0 SG A:CYS109 2.1 35.8 1.0 NE2 A:HIS117 2.2 43.9 1.0 CE1 A:HIS117 2.7 50.4 1.0 CD A:GLU132 2.9 34.3 1.0 CE1 A:HIS98 2.9 34.4 1.0 OE1 A:GLU132 3.0 30.4 1.0 CB A:CYS109 3.0 35.2 1.0 CD2 A:HIS98 3.1 32.8 1.0 CD2 A:HIS117 3.5 49.0 1.0 CA A:CYS109 3.8 35.6 1.0 ND1 A:HIS117 4.0 52.3 1.0 ND1 A:HIS98 4.1 33.7 1.0 CG A:HIS98 4.2 30.4 1.0 O A:HOH330 4.2 38.8 1.0 O A:HIS111 4.3 64.7 1.0 CG A:GLU132 4.3 29.7 1.0 CG A:HIS117 4.4 49.6 1.0 C A:CYS109 4.5 42.4 1.0 OG A:SER114 4.5 69.5 1.0 N A:HIS110 4.5 40.0 1.0 O A:GLY95 4.6 46.4 1.0 CD2 A:HIS110 4.6 81.5 1.0 CG2 A:VAL119 4.7 29.1 1.0 N A:CYS109 5.0 38.4 1.0 N A:HIS111 5.0 60.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Holo Xczur


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Holo Xczur within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:33.5 occ:1.00 SG A:CYS127 2.2 32.4 1.0 SG A:CYS124 2.3 29.7 1.0 SG A:CYS164 2.4 32.3 1.0 SG A:CYS167 2.4 37.4 1.0 CB A:CYS124 3.2 29.4 1.0 CB A:CYS127 3.2 35.3 1.0 CB A:CYS167 3.4 34.6 1.0 CB A:CYS164 3.5 27.2 1.0 N A:CYS127 3.7 36.3 1.0 N A:CYS164 3.9 32.0 1.0 CA A:CYS127 4.0 33.3 1.0 N A:CYS167 4.2 27.6 1.0 CA A:CYS164 4.2 31.2 1.0 O A:HOH334 4.3 37.9 1.0 OG A:SER129 4.4 34.7 1.0 CA A:CYS167 4.4 30.0 1.0 CA A:CYS124 4.6 26.8 1.0 C A:CYS127 4.7 37.0 1.0 C A:CYS164 4.8 29.2 1.0 C A:ARG126 4.8 38.1 1.0 O A:CYS164 4.8 35.5 1.0 CB A:ARG126 4.9 24.2 1.0 N A:HIS128 4.9 33.1 1.0 N A:ARG126 5.0 30.6 1.0

F.Liu, Z.Su, P.Chen, X.Tian, L.Wu, D.J.Tang, P.Li, H.Deng, P.Ding, Q.Fu, J.L.Tang, Z.Ming. Structural Basis For Zinc-Induced Activation of A Zinc Uptake Transcriptional Regulator. Nucleic Acids Res. 2021.
ISSN: ESSN 1362-4962
PubMed: 34048589
DOI: 10.1093/NAR/GKAB432