Zinc in PDB 7ckm: Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex)

All present enzymatic activity of Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex):
2.7.7.48;

The structure of Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex) also contains other interesting chemical elements:

Manganese

(Mn)

1 atom

The binding sites of Zinc atom in the Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex) (pdb code 7ckm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex), PDB code: 7ckm:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2302 b:103.5 occ:1.00 ND1 A:HIS472 2.1 44.5 1.0 SG A:CYS287 2.4 35.0 1.0 SG A:CYS284 2.4 33.3 1.0 SG A:CYS470 2.4 81.6 1.0 CE1 A:HIS472 2.8 44.5 1.0 CG A:HIS472 3.2 44.5 1.0 CB A:CYS284 3.3 33.3 1.0 CB A:CYS470 3.4 81.6 1.0 CB A:HIS472 3.7 44.5 1.0 CB A:CYS287 3.8 35.0 1.0 NE2 A:HIS472 4.0 44.5 1.0 CA A:CYS470 4.1 81.6 1.0 N A:CYS287 4.1 35.0 1.0 CD2 A:HIS472 4.2 44.5 1.0 CA A:CYS287 4.4 35.0 1.0 N A:ARG471 4.6 72.1 1.0 C A:CYS470 4.6 81.6 1.0 CA A:CYS284 4.8 33.3 1.0 N A:HIS472 4.8 44.5 1.0 CA A:HIS472 4.9 44.5 1.0 C A:PHE286 4.9 24.1 1.0 CB A:PHE286 4.9 24.1 1.0

Zinc binding site 2 out of 4 in the Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2303 b:132.2 occ:1.00 SG A:CYS1650 2.4 82.2 1.0 SG A:CYS1652 2.4 81.3 1.0 SG A:CYS1655 2.4 64.8 1.0 SG A:CYS1664 2.4 55.6 1.0 CB A:CYS1655 2.8 64.8 1.0 N A:CYS1652 3.2 81.3 1.0 OG A:SER1667 3.4 57.5 1.0 N A:CYS1655 3.6 64.8 1.0 CB A:CYS1664 3.7 55.6 1.0 CB A:CYS1652 3.7 81.3 1.0 CA A:CYS1655 3.8 64.8 1.0 N A:THR1651 3.9 81.9 1.0 CA A:CYS1652 3.9 81.3 1.0 C A:THR1651 4.2 81.9 1.0 CB A:CYS1650 4.2 82.2 1.0 CA A:THR1651 4.2 81.9 1.0 N A:CYS1664 4.3 55.6 1.0 C A:CYS1652 4.5 81.3 1.0 CA A:CYS1664 4.6 55.6 1.0 C A:ILE1654 4.6 66.8 1.0 N A:ILE1654 4.6 66.8 1.0 CB A:SER1667 4.7 57.5 1.0 C A:CYS1650 4.7 82.2 1.0 OD1 A:ASN1666 4.8 57.3 1.0 N A:GLU1653 4.8 73.5 1.0 C A:CYS1655 4.8 64.8 1.0 CG2 A:ILE1654 4.8 66.8 1.0

Zinc binding site 3 out of 4 in the Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn101 b:124.3 occ:1.00 SG B:CYS39 2.3 42.3 1.0 SG B:CYS58 2.3 57.1 1.0 SG B:CYS61 2.3 56.5 1.0 CB B:CYS58 2.4 57.1 1.0 SG B:CYS42 2.4 34.6 1.0 CB B:CYS39 2.9 42.3 1.0 CB B:CYS61 3.7 56.5 1.0 CA B:CYS58 3.7 57.1 1.0 N B:CYS58 4.0 57.1 1.0 CB B:CYS42 4.0 34.6 1.0 CB B:ALA45 4.3 33.9 1.0 N B:CYS42 4.3 34.6 1.0 CA B:CYS39 4.3 42.3 1.0 N B:CYS61 4.7 56.5 1.0 C B:CYS58 4.7 57.1 1.0 CB B:CYS41 4.8 37.1 1.0 CA B:CYS42 4.8 34.6 1.0 CA B:CYS61 4.8 56.5 1.0 C B:CYS39 5.0 42.3 1.0

Zinc binding site 4 out of 4 in the Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of Machupo Virus Polymerase Bound to Z Matrix Protein (Monomeric Complex) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn102 b:85.5 occ:1.00 NE2 B:HIS55 2.0 63.5 1.0 CE1 B:HIS55 2.3 63.5 1.0 SG B:CYS75 2.4 46.8 1.0 SG B:CYS72 2.4 57.5 1.0 SG B:CYS52 2.4 73.1 1.0 CB B:CYS52 3.0 73.1 1.0 CG2 B:ILE74 3.2 48.0 1.0 CB B:CYS75 3.4 46.8 1.0 CD2 B:HIS55 3.4 63.5 1.0 ND1 B:HIS55 3.6 63.5 1.0 N B:CYS75 3.8 46.8 1.0 CB B:CYS72 3.9 57.5 1.0 CG B:HIS55 4.1 63.5 1.0 O B:CYS52 4.2 73.1 1.0 CA B:CYS75 4.2 46.8 1.0 CD2 B:LEU57 4.3 53.8 1.0 CA B:CYS52 4.4 73.1 1.0 C B:ILE74 4.4 48.0 1.0 CB B:ILE74 4.5 48.0 1.0 C B:CYS52 4.7 73.1 1.0 CD2 B:LEU79 4.8 58.1 1.0 CA B:ILE74 4.9 48.0 1.0

X.Xu, R.Peng, Q.Peng, Y.Shi. Structure of Machupo Virus Polymerase Bound to Z Matrix Protein To Be Published.