Zinc in PDB 7btf: Sars-Cov-2 Rna-Dependent Rna Polymerase in Complex with Cofactors in Reduced Condition

Zinc Binding Sites:

The binding sites of Zinc atom in the Sars-Cov-2 Rna-Dependent Rna Polymerase in Complex with Cofactors in Reduced Condition (pdb code 7btf). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sars-Cov-2 Rna-Dependent Rna Polymerase in Complex with Cofactors in Reduced Condition, PDB code: 7btf:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 7btf

Go back to Zinc Binding Sites List in 7btf
Zinc binding site 1 out of 2 in the Sars-Cov-2 Rna-Dependent Rna Polymerase in Complex with Cofactors in Reduced Condition


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Rna-Dependent Rna Polymerase in Complex with Cofactors in Reduced Condition within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1001

b:59.1
occ:1.00
ND1 A:HIS295 2.6 37.7 1.0
SG A:CYS301 2.8 43.7 1.0
SG A:CYS310 2.8 37.2 1.0
SG A:CYS306 2.9 40.4 1.0
CB A:HIS295 3.3 37.7 1.0
CG A:HIS295 3.4 37.7 1.0
O A:CYS306 3.6 40.4 1.0
CB A:CYS301 3.6 43.7 1.0
CB A:CYS310 3.6 37.2 1.0
CA A:CYS301 3.7 43.7 1.0
CE1 A:HIS295 3.7 37.7 1.0
CB A:CYS306 4.0 40.4 1.0
C A:CYS306 4.0 40.4 1.0
N A:HIS295 4.2 37.7 1.0
CA A:HIS295 4.3 37.7 1.0
N A:CYS301 4.4 43.7 1.0
CA A:CYS306 4.6 40.4 1.0
O A:HIS295 4.6 37.7 1.0
CD2 A:HIS295 4.6 37.7 1.0
N A:ILE307 4.7 37.6 1.0
NE2 A:HIS295 4.7 37.7 1.0
O A:ASN300 4.8 42.3 1.0
C A:ASN300 4.9 42.3 1.0
C A:CYS301 4.9 43.7 1.0
CA A:CYS310 5.0 37.2 1.0
CA A:ILE307 5.0 37.6 1.0
N A:LEU302 5.0 42.8 1.0
C A:HIS295 5.0 37.7 1.0

Zinc binding site 2 out of 2 in 7btf

Go back to Zinc Binding Sites List in 7btf
Zinc binding site 2 out of 2 in the Sars-Cov-2 Rna-Dependent Rna Polymerase in Complex with Cofactors in Reduced Condition


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Cov-2 Rna-Dependent Rna Polymerase in Complex with Cofactors in Reduced Condition within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1002

b:65.5
occ:1.00
SG A:CYS487 2.3 45.8 1.0
ND1 A:HIS642 2.5 43.5 1.0
SG A:CYS646 2.7 49.2 1.0
SG A:CYS645 2.8 50.7 1.0
CG A:HIS642 3.1 43.5 1.0
CB A:CYS487 3.4 45.8 1.0
CE1 A:HIS642 3.4 43.5 1.0
CB A:HIS642 3.4 43.5 1.0
N A:CYS487 3.5 45.8 1.0
CE1 A:PHE571 3.9 41.7 1.0
CA A:CYS487 3.9 45.8 1.0
CB A:CYS646 4.0 49.2 1.0
CB A:CYS645 4.1 50.7 1.0
CD2 A:HIS642 4.2 43.5 1.0
CD1 A:PHE571 4.2 41.7 1.0
C A:GLY486 4.2 43.9 1.0
NE2 A:HIS642 4.3 43.5 1.0
CA A:HIS642 4.5 43.5 1.0
N A:CYS646 4.6 49.2 1.0
CA A:GLY486 4.6 43.9 1.0
CZ A:PHE571 4.8 41.7 1.0
NZ A:LYS532 4.9 38.4 1.0
C A:CYS645 4.9 50.7 1.0
CA A:CYS646 4.9 49.2 1.0

Reference:

Y.Gao, L.Yan, Y.Huang, F.Liu, Y.Zhao, L.Cao, T.Wang, Q.Sun, Z.Ming, L.Zhang, J.Ge, L.Zheng, Y.Zhang, H.Wang, Y.Zhu, C.Zhu, T.Hu, T.Hua, B.Zhang, X.Yang, J.Li, H.Yang, Z.Liu, W.Xu, L.W.Guddat, Q.Wang, Z.Lou, Z.Rao. Structure of Rna-Dependent Rna Polymerase From 2019-Ncov, A Major Antiviral Drug Target Biorxiv 2020.
DOI: 10.1101/2020.03.16.993386
Page generated: Wed Dec 16 13:36:27 2020

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