Zinc in PDB 7bq7: Crystal Structure of 2019-Ncov NSP16-NSP10 Complex

All present enzymatic activity of Crystal Structure of 2019-Ncov NSP16-NSP10 Complex:
2.7.7.48; 3.4.19.12; 3.4.22.69; 3.6.4.12; 3.6.4.13;

The structure of Crystal Structure of 2019-Ncov NSP16-NSP10 Complex, PDB code: 7bq7 was solved by L.M.Yan, Y.C.Huang, Z.Y.Lou, Z.H.Rao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.22 / 2.37
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	170.156, 170.156, 52.218, 90.00, 90.00, 120.00
R / Rfree (%)	18 / 20.9

The binding sites of Zinc atom in the Crystal Structure of 2019-Ncov NSP16-NSP10 Complex (pdb code 7bq7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of 2019-Ncov NSP16-NSP10 Complex, PDB code: 7bq7:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of 2019-Ncov NSP16-NSP10 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of 2019-Ncov NSP16-NSP10 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn200 b:0.4 occ:0.00 SG B:CYS117 2.0 70.2 1.0 SG B:CYS130 2.2 89.7 1.0 CB B:CYS120 2.3 80.5 1.0 CB B:CYS128 2.8 77.8 1.0 SG B:CYS120 3.0 0.0 1.0 CB B:CYS117 3.2 78.4 1.0 CB B:CYS130 3.2 85.3 1.0 CA B:CYS128 3.5 80.6 1.0 CA B:CYS120 3.7 79.9 1.0 N B:SER129 3.9 79.9 1.0 N B:CYS120 3.9 81.0 1.0 N B:CYS130 4.0 88.0 1.0 C B:CYS128 4.0 79.7 1.0 CA B:CYS130 4.2 87.5 1.0 CG2 B:VAL119 4.3 79.1 1.0 SG B:CYS128 4.4 80.9 1.0 CA B:CYS117 4.7 73.6 1.0 C B:SER129 4.7 87.8 1.0 C B:CYS120 4.9 79.0 1.0 N B:CYS128 4.9 74.5 1.0 CA B:SER129 4.9 84.9 1.0 O B:CYS128 5.0 76.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of 2019-Ncov NSP16-NSP10 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of 2019-Ncov NSP16-NSP10 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:57.9 occ:0.00 SG B:CYS90 1.7 59.6 1.0 NE2 B:HIS83 2.2 60.5 1.0 CB B:CYS74 2.5 52.3 1.0 CD2 B:HIS83 3.0 57.9 1.0 SG B:CYS77 3.0 59.6 1.0 SG B:CYS74 3.2 36.6 1.0 CE1 B:HIS83 3.2 59.6 1.0 CB B:CYS90 3.3 64.2 1.0 CB B:CYS77 3.7 49.4 1.0 N B:CYS77 3.7 50.8 1.0 CA B:CYS74 3.9 55.6 1.0 CG B:HIS83 4.2 64.9 1.0 CA B:CYS77 4.2 51.1 1.0 ND1 B:HIS83 4.3 57.9 1.0 CA B:CYS90 4.3 65.8 1.0 CB B:TYR76 4.3 55.7 1.0 C B:CYS74 4.5 52.8 1.0 C B:TYR76 4.6 54.3 1.0 CD2 B:TYR76 4.6 58.3 1.0 N B:TYR76 4.8 48.0 1.0 CA B:TYR76 4.8 52.0 1.0 O B:CYS74 4.8 52.0 1.0 N B:CYS74 4.9 53.6 1.0

L.M.Yan, Y.C.Huang, Z.Y.Lou, Z.H.Rao. Crystal Structure of 2019-Ncov NSP16-NSP10 Complex To Be Published.