Zinc in PDB 7bez: Zinc Bound Domain 3 of Carbonic Anhydrase From Marine Diatom Thalassiosira Weissflogii

The structure of Zinc Bound Domain 3 of Carbonic Anhydrase From Marine Diatom Thalassiosira Weissflogii, PDB code: 7bez was solved by V.Alterio, G.De Simone, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.24 / 1.98
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	117.754, 62.511, 75.397, 90, 120.06, 90
R / Rfree (%)	20.9 / 24.3

The binding sites of Zinc atom in the Zinc Bound Domain 3 of Carbonic Anhydrase From Marine Diatom Thalassiosira Weissflogii (pdb code 7bez). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Zinc Bound Domain 3 of Carbonic Anhydrase From Marine Diatom Thalassiosira Weissflogii, PDB code: 7bez:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Zinc Bound Domain 3 of Carbonic Anhydrase From Marine Diatom Thalassiosira Weissflogii


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Zinc Bound Domain 3 of Carbonic Anhydrase From Marine Diatom Thalassiosira Weissflogii within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn700 b:24.8 occ:1.00 NE2 A:HIS525 2.0 25.2 1.0 O A:HOH810 2.1 22.6 1.0 SG A:CYS473 2.3 22.4 1.0 SG A:CYS535 2.3 22.6 1.0 CE1 A:HIS525 2.9 25.5 1.0 CD2 A:HIS525 3.1 21.6 1.0 CB A:CYS535 3.2 24.4 1.0 CB A:CYS473 3.2 20.8 1.0 O A:HOH864 3.3 33.6 1.0 CA A:CYS535 3.4 24.8 1.0 N A:GLY536 3.9 23.4 1.0 C A:CYS535 4.0 25.1 1.0 ND1 A:HIS525 4.1 20.9 1.0 OD2 A:ASP475 4.1 27.7 1.0 CG A:HIS525 4.2 22.4 1.0 CA A:GLY491 4.2 20.1 1.0 CB A:ASP475 4.2 23.5 1.0 N A:GLY491 4.3 20.9 1.0 O A:HOH827 4.3 20.4 1.0 N A:PHE537 4.5 22.0 1.0 CA A:CYS473 4.7 20.3 1.0 CG A:ASP475 4.7 25.8 1.0 N A:CYS535 4.7 27.6 1.0 CB A:PHE537 4.8 19.7 1.0 O A:CYS535 4.9 25.8 1.0 N A:ASP475 4.9 23.0 1.0 O A:GLY534 4.9 30.3 1.0

Zinc binding site 2 out of 2 in the Zinc Bound Domain 3 of Carbonic Anhydrase From Marine Diatom Thalassiosira Weissflogii


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Zinc Bound Domain 3 of Carbonic Anhydrase From Marine Diatom Thalassiosira Weissflogii within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn700 b:23.9 occ:1.00 NE2 B:HIS93 2.0 23.7 1.0 O B:HOH805 2.1 24.8 1.0 SG B:CYS41 2.3 21.9 1.0 SG B:CYS103 2.3 21.3 1.0 CD2 B:HIS93 3.0 21.6 1.0 CE1 B:HIS93 3.1 21.7 1.0 CB B:CYS103 3.2 22.4 1.0 CB B:CYS41 3.2 22.4 1.0 CA B:CYS103 3.4 22.5 1.0 O B:HOH876 3.5 25.1 1.0 N B:GLY104 3.9 21.9 1.0 C B:CYS103 4.0 23.2 1.0 OD2 B:ASP43 4.1 29.6 1.0 ND1 B:HIS93 4.2 20.8 1.0 CG B:HIS93 4.2 22.1 1.0 CB B:ASP43 4.2 25.9 1.0 CA B:GLY59 4.3 21.9 1.0 N B:GLY59 4.3 21.1 1.0 N B:PHE105 4.5 21.8 1.0 O B:HOH860 4.7 20.7 1.0 CG B:ASP43 4.7 29.4 1.0 CA B:CYS41 4.7 23.7 1.0 N B:CYS103 4.8 24.5 1.0 CB B:PHE105 4.8 19.0 1.0 O B:CYS103 4.9 22.9 1.0 N B:ASP43 5.0 25.5 1.0 O B:GLY102 5.0 26.8 1.0

V.Alterio, E.Langella, M.Buonanno, D.Esposito, A.Nocentini, E.Berrino, S.Bua, M.Polentarutti, C.T.Supuran, S.M.Monti, G.De Simone. Zeta-Carbonic Anhydrases Show Cs 2 Hydrolase Activity: A New Metabolic Carbon Acquisition Pathway in Diatoms? Comput Struct Biotechnol J V. 19 3427 2021.
ISSN: ESSN 2001-0370
PubMed: 34194668
DOI: 10.1016/J.CSBJ.2021.05.057