Zinc in PDB 7aez: Crystal Structure of the Metallo-Beta-Lactamase Ndm-7 with 407

The structure of Crystal Structure of the Metallo-Beta-Lactamase Ndm-7 with 407, PDB code: 7aez was solved by J.Brem, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.72 / 1.02
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.746, 58.736, 83.897, 90, 90, 90
R / Rfree (%)	10.4 / 11.3

The structure of Crystal Structure of the Metallo-Beta-Lactamase Ndm-7 with 407 also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Zinc atom in the Crystal Structure of the Metallo-Beta-Lactamase Ndm-7 with 407 (pdb code 7aez). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Metallo-Beta-Lactamase Ndm-7 with 407, PDB code: 7aez:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Metallo-Beta-Lactamase Ndm-7 with 407


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Metallo-Beta-Lactamase Ndm-7 with 407 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:7.7 occ:0.95 O A:HOH435 1.9 8.7 1.0 NE2 A:HIS189 2.0 8.0 1.0 NE2 A:HIS120 2.0 7.5 1.0 ND1 A:HIS122 2.0 8.2 1.0 HB2 A:HIS122 3.0 8.7 1.0 CD2 A:HIS189 3.0 7.4 1.0 CE1 A:HIS120 3.0 7.3 1.0 CE1 A:HIS122 3.0 8.5 1.0 CE1 A:HIS189 3.0 8.1 1.0 CD2 A:HIS120 3.0 7.0 1.0 CG A:HIS122 3.1 7.6 1.0 HD2 A:HIS189 3.1 8.9 1.0 HE1 A:HIS120 3.2 8.8 1.0 HE1 A:HIS122 3.2 10.2 1.0 HE1 A:HIS189 3.2 9.7 1.0 HD2 A:HIS120 3.2 8.3 1.0 CB A:HIS122 3.4 7.3 1.0 H101 A:R8W301 3.5 9.8 0.8 HB3 A:HIS122 3.5 8.7 1.0 ZN A:ZN303 3.5 9.6 0.8 HG23 A:THR190 3.8 9.9 1.0 SG A:CYS208 3.9 8.2 1.0 O27 A:R8W301 3.9 7.1 0.8 OD1 A:ASP124 3.9 8.7 1.0 H033 A:R8W301 4.0 13.9 0.8 H021 A:R8W301 4.0 12.5 0.8 HG21 A:THR190 4.0 9.9 1.0 HB3 A:CYS208 4.0 9.2 1.0 ND1 A:HIS120 4.1 7.3 1.0 NE2 A:HIS122 4.1 8.9 1.0 ND1 A:HIS189 4.1 8.1 1.0 CG A:HIS189 4.1 7.4 1.0 CG A:HIS120 4.2 6.7 1.0 CD2 A:HIS122 4.2 8.5 1.0 CB A:CYS208 4.3 7.7 1.0 CG2 A:THR190 4.4 8.3 1.0 H031 A:R8W301 4.4 13.9 0.8 N10 A:R8W301 4.4 8.2 0.8 C03 A:R8W301 4.5 11.6 0.8 HG3 A:LYS125 4.5 9.5 1.0 OD2 A:ASP124 4.6 10.1 1.0 HG2 A:LYS125 4.6 9.5 1.0 CG A:ASP124 4.7 8.3 1.0 HG22 A:THR190 4.7 9.9 1.0 C02 A:R8W301 4.8 10.4 0.8 C25 A:R8W301 4.8 7.5 0.8 CA A:HIS122 4.9 7.0 1.0 HD1 A:HIS120 4.9 8.7 1.0 HE2 A:HIS122 4.9 10.7 1.0 HD1 A:HIS189 4.9 9.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Metallo-Beta-Lactamase Ndm-7 with 407


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Metallo-Beta-Lactamase Ndm-7 with 407 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn303 b:9.6 occ:0.75 O A:HOH435 2.0 8.7 1.0 OD2 A:ASP124 2.1 10.1 1.0 NE2 A:HIS250 2.1 8.8 1.0 O27 A:R8W301 2.2 7.1 0.8 SG A:CYS208 2.3 8.2 1.0 H101 A:R8W301 2.8 9.8 0.8 C25 A:R8W301 3.1 7.5 0.8 CG A:ASP124 3.1 8.3 1.0 CE1 A:HIS250 3.1 8.6 1.0 CD2 A:HIS250 3.1 8.9 1.0 N10 A:R8W301 3.1 8.2 0.8 HB3 A:CYS208 3.2 9.2 1.0 CB A:CYS208 3.3 7.7 1.0 HD2 A:HIS250 3.3 10.7 1.0 HE1 A:HIS250 3.3 10.4 1.0 C11 A:R8W301 3.3 7.3 0.8 OD1 A:ASP124 3.4 8.7 1.0 ZN A:ZN302 3.5 7.7 0.9 HB3 A:SER249 3.9 10.1 1.0 H021 A:R8W301 4.0 12.5 0.8 HB2 A:SER249 4.0 10.1 1.0 HG A:SER249 4.1 10.5 1.0 HE1 A:HIS120 4.1 8.8 1.0 HE3 A:LYS125 4.1 10.9 1.0 NE2 A:HIS189 4.2 8.0 1.0 O26 A:R8W301 4.2 8.4 0.8 ND1 A:HIS250 4.2 8.6 1.0 C09 A:R8W301 4.2 8.6 0.8 HE1 A:HIS189 4.2 9.7 1.0 CG A:HIS250 4.2 8.8 1.0 CB A:SER249 4.4 8.4 1.0 CE1 A:HIS189 4.4 8.1 1.0 CB A:ASP124 4.4 7.7 1.0 C12 A:R8W301 4.5 8.4 0.8 HG2 A:LYS125 4.5 9.5 1.0 HB2 A:ASP124 4.5 9.2 1.0 HD2 A:LYS125 4.6 10.2 1.0 CA A:CYS208 4.6 7.8 1.0 NE2 A:HIS120 4.6 7.5 1.0 HZ1 A:LYS211 4.6 12.1 1.0 HB3 A:ASP124 4.7 9.2 1.0 H141 A:R8W301 4.7 12.9 0.8 CE1 A:HIS120 4.7 7.3 1.0 OG A:SER249 4.7 8.8 1.0 C02 A:R8W301 4.9 10.4 0.8 C08 A:R8W301 5.0 8.4 0.8 CE A:LYS125 5.0 9.1 1.0 HD1 A:HIS250 5.0 10.3 1.0 C04 A:R8W301 5.0 9.3 0.8

J.Brem, C.J.Schofield. Not Available Yet To Be Published.