Zinc in PDB 6zxd: Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F1

All present enzymatic activity of Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F1:
2.7.11.1; 4.2.99.18;

The binding sites of Zinc atom in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F1 (pdb code 6zxd). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F1, PDB code: 6zxd:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F1 within 5.0Å range: probe atom residue distance (Å) B Occ 2:Zn1901 b:45.1 occ:1.00 C4 2:U1308 2.4 51.2 1.0 C5 2:C1309 2.4 46.5 1.0 C5 2:U1308 2.5 51.2 1.0 N4 2:C1309 2.5 46.5 1.0 O4 2:U1308 2.6 51.2 1.0 C4 2:C1309 2.8 46.5 1.0 N3 2:U1308 3.1 51.2 1.0 C6 2:U1308 3.2 51.2 1.0 C6 2:C1309 3.5 46.5 1.0 C2 2:U1308 3.8 51.2 1.0 N1 2:U1308 3.8 51.2 1.0 N3 2:C1309 4.1 46.5 1.0 O4 2:U1310 4.2 44.8 1.0 N1 2:C1309 4.6 46.5 1.0 C4 2:U1310 4.7 44.8 1.0 O2 2:U1308 4.8 51.2 1.0 C2 2:C1309 4.9 46.5 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of A Late Human Pre-40S Ribosomal Subunit - State F1 within 5.0Å range: probe atom residue distance (Å) B Occ y:Zn500 b:13.8 occ:1.00 SG y:CYS270 2.4 7.3 1.0 SG y:CYS288 2.4 6.9 1.0 SG y:CYS285 2.4 6.3 1.0 SG y:CYS273 2.4 7.1 1.0 CB y:CYS270 2.7 7.3 1.0 CB y:CYS285 2.9 6.3 1.0 CB y:CYS288 3.6 6.9 1.0 CB y:CYS273 3.6 7.1 1.0 N y:CYS288 4.0 6.9 1.0 N y:CYS273 4.1 7.1 1.0 CA y:CYS270 4.3 7.3 1.0 CA y:CYS285 4.4 6.3 1.0 CA y:CYS288 4.4 6.9 1.0 CA y:CYS273 4.4 7.1 1.0 OG1 y:THR292 4.4 5.4 1.0 C y:CYS285 4.9 6.3 1.0 N y:GLY289 5.0 5.1 1.0 C y:CYS270 5.0 7.3 1.0

M.Ameismeier, I.Zemp, J.Van Den Heuvel, M.Thoms, O.Berninghausen, U.Kutay, R.Beckmann. Structural Basis For the Final Steps of Human 40S Ribosome Maturation. Nature V. 587 683 2020.
ISSN: ESSN 1476-4687
PubMed: 33208940
DOI: 10.1038/S41586-020-2929-X