Zinc in PDB 6zr2: Cryo-Em Structure of Respiratory Complex I in the Active State From Mus Musculus at 3.1 A

All present enzymatic activity of Cryo-Em Structure of Respiratory Complex I in the Active State From Mus Musculus at 3.1 A:
7.1.1.2;

The structure of Cryo-Em Structure of Respiratory Complex I in the Active State From Mus Musculus at 3.1 A also contains other interesting chemical elements:

Iron

(Fe)

28 atoms

The binding sites of Zinc atom in the Cryo-Em Structure of Respiratory Complex I in the Active State From Mus Musculus at 3.1 A (pdb code 6zr2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Respiratory Complex I in the Active State From Mus Musculus at 3.1 A, PDB code: 6zr2:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Respiratory Complex I in the Active State From Mus Musculus at 3.1 A


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Respiratory Complex I in the Active State From Mus Musculus at 3.1 A within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn201 b:39.0 occ:1.00 NE2 R:HIS68 2.0 21.2 1.0 SG R:CYS84 2.3 23.3 1.0 SG R:CYS87 2.3 22.4 1.0 SG R:CYS59 2.4 24.6 1.0 CE1 R:HIS68 2.7 21.2 1.0 CD2 R:HIS68 3.2 21.2 1.0 CB R:CYS84 3.2 23.3 1.0 CB R:CYS87 3.4 22.4 1.0 CB R:CYS59 3.5 24.6 1.0 ND1 R:HIS68 3.8 21.2 1.0 N R:CYS87 3.9 22.4 1.0 CG R:HIS68 4.1 21.2 1.0 O R:CYS59 4.1 24.6 1.0 CA R:CYS87 4.2 22.4 1.0 O R:ASP60 4.2 24.1 1.0 C R:CYS59 4.3 24.6 1.0 C R:ASP60 4.5 24.1 1.0 CA R:CYS59 4.5 24.6 1.0 C R:CYS87 4.7 22.4 1.0 CA R:CYS84 4.7 23.3 1.0 N R:GLY61 4.8 22.3 1.0 O R:CYS87 4.8 22.4 1.0 CB R:TYR86 4.9 20.3 1.0 N R:ASP60 4.9 24.1 1.0 CA R:GLY61 5.0 22.3 1.0 CA R:ASP60 5.0 24.1 1.0

H.R.Bridges, J.G.Fedor, J.N.Blaza, A.Di Luca, A.Jussupow, O.D.Jarman, J.J.Wright, A.A.Agip, A.P.Gamiz-Hernandez, M.M.Roessler, V.R.I.Kaila, J.Hirst. Structure of Inhibitor-Bound Mammalian Complex I. Nat Commun V. 11 5261 2020.
ISSN: ESSN 2041-1723
PubMed: 33067417
DOI: 10.1038/S41467-020-18950-3