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Zinc in PDB 6yjy: Crystal Structure of Human Glutaminyl Cyclase in Complex with Neurotensin 1-5Enzymatic activity of Crystal Structure of Human Glutaminyl Cyclase in Complex with Neurotensin 1-5
All present enzymatic activity of Crystal Structure of Human Glutaminyl Cyclase in Complex with Neurotensin 1-5:
2.3.2.5; Protein crystallography data
The structure of Crystal Structure of Human Glutaminyl Cyclase in Complex with Neurotensin 1-5, PDB code: 6yjy
was solved by
L.M.Funk,
V.Sautner,
K.Tittmann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Glutaminyl Cyclase in Complex with Neurotensin 1-5
(pdb code 6yjy). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Glutaminyl Cyclase in Complex with Neurotensin 1-5, PDB code: 6yjy: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 6yjyGo back to Zinc Binding Sites List in 6yjy
Zinc binding site 1 out
of 2 in the Crystal Structure of Human Glutaminyl Cyclase in Complex with Neurotensin 1-5
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 6yjyGo back to Zinc Binding Sites List in 6yjy
Zinc binding site 2 out
of 2 in the Crystal Structure of Human Glutaminyl Cyclase in Complex with Neurotensin 1-5
Mono view Stereo pair view
Reference:
O.Kupski,
L.M.Funk,
V.Sautner,
F.Seifert,
B.Worbs,
D.Ramsbeck,
F.Meyer,
U.Diederichsen,
M.Buchholz,
S.Schilling,
H.U.Demuth,
K.Tittmann.
Hydrazides Are Potent Transition-State Analogues For Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer'S Disease. Biochemistry V. 59 2585 2020.
Page generated: Wed Dec 16 13:16:56 2020
ISSN: ISSN 0006-2960 PubMed: 32551535 DOI: 10.1021/ACS.BIOCHEM.0C00337 |
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